Unusual Features of the SARS-CoV-2 Genome Suggesting Sophisticated
Laboratory Modification Rather Than Natural Evolution and Delineation of Its Probable Synthetic Route; Li-Meng Yan (MD, PhD)
"The alternative theory that the virus may have come from a
research laboratory is, however, strictly censored on peer-reviewed scientific journals. Nonetheless,
SARS-CoV-2 shows biological characteristics that are inconsistent with a naturally occurring, zoonotic
virus...
In this report, we describe the genomic, structural, medical, and literature evidence, which, when considered together, strongly contradicts the natural origin theory." Li-Meng Yan (MD, PhD)

zenodo.org/record/4028830
'Abundant literature indicates that gain-of-function research has long
advanced to the stage where viral genomes can be precisely engineered and manipulated to enable the
creation of novel coronaviruses possessing unique properties.'
'The genomic sequence of SARS-CoV-2 is suspiciously similar to that of a bat coronavirus discovered by military laboratories in the Third Military Medical University (Chongqing, China)
and the Research Institute for Medicine of Nanjing Command (Nanjing, China).'
'The receptor-binding motif (RBM) within the Spike protein of SARS-CoV-2, which determines the host specificity of the virus, resembles that of SARS-CoV from the 2003 epidemic in a suspicious manner. Genomic evidence suggests that the RBM has been genetically manipulated.'
'SARS-CoV-2 contains a unique furin-cleavage site in its Spike protein, which is known to greatly enhance viral infectivity and cell tropism. Yet, this cleavage site is completely absent in this particular class of coronaviruses found in nature...
In addition, rare codons associated with this
additional sequence suggest the strong possibility that this furin-cleavage site is not the product of natural evolution and could have been inserted into the SARS-CoV-2 genome artificially by techniques ...
other than simple serial passage or multi-strain recombination events inside co-infected
tissue cultures or animals.'

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