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Tom Inglesby, MD

@T_Inglesby

Apr 12

The testing approach to H5N1 in cattle (in the link) needs to change substantially. @USDA_APHIS may be doing what it can now with minimal resources, but testing needs to expand, get simpler, more available and transparent.
1/xaphis.usda.gov/sites/default/…

The testing protocol is too complicated. It also only allows testing in cows that meet a specific profile. It only provides for limited number of tests per premises. 2/x

Given the quickly increasing number of farms w/ infected cows, the number of farms that are impacted that have had minimal interaction with others, the uncertainty on mechanism of spread and extent of disease, testing for H5N1 in cattle should change in a number of ways asap: 3/x

Read 8 tweets

Tom Inglesby, MD

@T_Inglesby

Oct 30, 2023

I want to commend the Biden Admin for its new Executive Order on #AI - strong leadership & action on ensuring safe, secure development of AI, both to pursue all of it's great promise, but also to address serious biological risks and dangers (1/9)whitehouse.gov/briefing-room/…

The EO rightly commits to attracting world’s leading AI talent, to using AI to drive innovation. AI will help accelerate new vaccines + therapeutics, improve access to Dx tools, help w/ forecasting, etc. But EO recognizes strong governance also needed to prevent misuse (2/9)

The EO requires OSTP to establish a gene synthesis screening framework that reduces risks that dangerous viruses will be created de novo in a lab. It requires criteria & mechanisms for identifying high risk orders, screening customers, processes for reporting concerns (3/9)

Read 9 tweets

Tom Inglesby, MD

@T_Inglesby

Dec 15, 2022

Important and good new COVID Winter Preparedness plan and actions announced today by Administration. Sets out plans of the Admin and its local gov & community partners to cope with rising COVID hospitalizations and mortality in country. 1/x whitehouse.gov/briefing-room/…

COVID cases and hospitalizations are up in most US states across the country, COVID deaths are rising nationally. And wastewater monitoring shows increasing COVID in all regions. So this Winter Preparedness Plan from the Administration is important 2/x nytimes.com/interactive/20…

Households can now order 4 more COVID home tests through COVIDtests.gov starting today. This is in addition to continued coverage of 8 free tests a month through private insurance and Medicare; thousands of free testing sites across country. 3/x

Read 11 tweets

Tom Inglesby, MD

@T_Inglesby

Oct 25, 2022

So glad to moderate the panel conversation on Catastrophic Contagion and pandemic preparedness w/ distinguished colleagues Drs. Bemo, Hanefeld and Ryan, today in Brussels at the Gates Foundation sponsored Grand Challenges meeting 1/x

A few themes and lessons coming out of that conversation: 2/x

Preparing and responding to epidemics can't be flown in from the outside. Needs to be built from the ground up with investment, strong leadership and good regional partnership 3/x

Read 11 tweets

Tom Inglesby, MD

@T_Inglesby

Oct 24, 2022

@gatesfoundation

We just completed the quite valuable Catastrophic Contagion pandemic exercise in Brussels, in partnership with @gatesfoundation and @WHO at the Grand Challenges annual meeting 1/x

The extraordinary group of participants were comprised of 10 current / past Health Ministers and senior public health officials from Senegal, Rwanda, Nigeria, Angola, Liberia, Singapore, India, Germany, and the US, as well as Mr. Bill Gates 2/x

The exercise simulated a series of WHO health advisory board meetings in a fictional pandemic set in the near future. Participants grappled with an epidemic located in one part of the world that spread rapidly to become pandemic 3/x

Read 17 tweets

Tom Inglesby, MD

@T_Inglesby

Oct 18, 2022

The White House released the National Biodefense Strategy today. Compelling strategic goals, specific actions needed to get to them, many ambitious targets, clear assignment of lead agencies to get them done. Now its up to Congress to provide means to get all this work done 1/x

Hard-to-reach concrete goals include: 100 days to develop a vaccine, 130 days to manufacture enough for all of US, novel therapies produced within 180 days, 14 days to set up a clinical trial system, population uptake of vaccine at 85% and others along those lines. 2/x

Internationally, the US commits to help 50 countries to reach a range of specific epidemic related capabilities. This work is clearly important because epidemics that rage out of control anywhere are a threat to the US and the rest of the world. 3/x

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