The COVAX Facility aims to provide fair & equal access to the Covid vaccine for 7.8 billion people.
To commemorate 🇲🇾's entry into COVAX, I'll spend this week on some fun vaccine facts.
Fact 1: Edward Jenner discovered the concept of vaccination in 1796, ~220 years ago. (1/6)
For many years, he heard stories that dairymaids don’t get smallpox if they’ve had cowpox previously. Dairymaids spend a lot of time with cows to make milk or cheeses in a dairy.
This pic is cowpox. (2/6)
A young dairymaid had fresh cowpox. Jenner transferred some material from her skin lesions to an 8-year old boy’s skin. The boy had some mild fever but was otherwise quite well.
2 months later, Jenner repeated with smallpox but the boy had no fever.
This pic is smallpox. (3/6)
This proves the theory that “giving people very small amounts of a virus or bacteria can trigger their immune system to help fight future infections of the same virus or bacteria”.
This pic shows how vaccines work. (4/6)
The Latin word for cow is vacca, and cowpox is vaccinia.
Therefore, Jenner decided to call this new concept “vaccination”. (5/6)
Although… some historians think that Jenner used horsepox, not cowpox. So instead of vaccine, perhaps we should call it “equusine”!
This shows that science continues to progress, because our instruments & tools become more precise & sophisticated. 🧪🔬🧬💉 (6/6)
A: Possibly, and data is increasing to support this policy.
A "mix-and-match" vaccines policy has increasing science behind it. The scientific term is "heterologous prime boost" (thelancet.com/journals/lance……, from Oxford).
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Dua sebab penting:
🔺Saya tak mungkin tahu segala-gala ilmu & sains. Jadi, saya bergantung pada rakan sekerja yg lebih arif dlm bidang-bidang lain.
🔺Saya mungkin silap, jadi saya ingin kurangkan risiko itu.
Maka, Surat Rujukan akan menjaga kebajikan pesakit dgn lebih rapi.
2/
Mungkin saya pernah menulis beratus-ratus Surat Rujukan, spt kpd:
🔺Pakar jantung di Kuala Lumpur & Pulau Pinang
🔺Surat rujukan/sokongan utk Jabatan Kebajikan & badan zakat
🔺Rumah Seri Kenangan supaya mereka tahu keadaan fizikal seseorang warga emas yang baru sampai.
3/
A short story:
🔺A Funeral, Durians, SMEs & the Covid-19 Vaccines🔺
Had to organise a funeral (cause of death: lung cancer). Noticed dry ice being used.
Spoke with the undertaker, who told me that each dry ice brick is ~RM20, is -70 Celcius and lasts ~1-2 days.
1/5
Asked him about vaccine storage. He gave two ideas: 1. Ice-cream distributors have cold rooms reaching -20C. 2. Durian exporters to China use a freezing process reaching -80C.
Great ideas from a practical hands-on man!
2/5
This gentleman doesn’t have a degree, but he has decades of work experience & lots of common sense.
I told him that one Covid-19 vaccine requires -70C storage. He educated me that Siberia’s temperatures are “only” -60C, so human beings need to work hard to achieve -70C.
3/5
BEBENANG: Mengapa 🇲🇾 tak boleh umumkan harga vaksin?
Situasi ini amat kompleks. Kita mesti mempertimbangkan hujah & realiti utk kedua-dua belah situasi ini.
🔺Bab 1: di LUAR kawalan kerajaan (Tweet 3-9)
🔺Bab 2. di DALAM kawalan kerajaan (10-16)
🔺Bab 3: ringkasan (17-18)
1/18
Pertama sekali, sedikit pengumuman: 1. Saya seorang perunding bebas. 2. Saya tak memiliki stok apa-apa sykt di mana-mana. 3. Saya bekerja di Pharma 8 tahun (2Y sbg Medical Manager di 🇸🇬 + 6Y sbg Ethics & Compliance Director di Dubai, Shanghai & Paris, utk EEMEA & China).
2/18
BAB 1: DI LUAR KAWALAN KERAJAAN
Sykt farmaseutikal (atau pharma) mempunyai 3 pelanggan utama: 1. Kerajaan (kementerian, hospital atau insurans kerajaan) 2. Entiti swasta (hospital swasta, pengedar atau ejen) 3. Organisasi global (@UNICEF membeli 2 bilion dos vaksin/tahun).
BEBENANG: 6 SEBAB mengapa 🇲🇾 perlukan portfolio vaksin drpd pelbagai syarikat, bukan drpd satu sykt sahaja:
1. Tiada sykt yg mampu bekalkan segala keperluan vaksin 🇲🇾. Kalaupun wujud, mesti setiap negara akan bersaing, & kita masih tak mampu bersaing dgn negara kaya.
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2. Bahaya kalau kita bergantung pada satu sykt saja.
Mungkin ada kluster Covid-19 di kilang mereka. Mungkin ribut taufan melanda kilang mereka.
Mungkin mereka naikkan harga sbb ada kuasa monopoli. Atau mungkin vaksin mereka tak diluluskan NPRA.
2/12
3. Virus Covid mungkin ada mutasi. Ini disebut "antigenic drift".
Jika 🇲🇾 ada satu vaksin saja, & vaksin tu tak berkesan terhadap mutasi tersebut, maka seluruh bekalan vaksin itu dah tak boleh digunakan.
Portfolio vaksin mengurangkan pendedahan kita kpd risiko mutasi.