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Alina Chan Profile picture
@Ayjchan
Sep 24, 2020 • 7 tweets • 2 min read • Read on X
For COVID-19, countries are getting so desperate that they're running human challenge trials or using vaccines that haven't passed phrase 3. What's the plan for the next pandemic? How will global pathogen sampling from nature generate vaccines that work against emerging threats?
Some countries are in such dire straits that they have made deals to allow Chinese Sinovac to perform phase 3 tests on their citizens. "The company is also planning clinical trials with thousands of volunteers in India, Brazil and Bangladesh." washingtonpost.com/world/asia_pac…
Other countries are considering giving up their territory or military alliances to ensure that they have priority access to vaccines. ft.com/content/853775…
Let's say that we have entered an era of pandemics. What measurably productive surveillance or vaccine strategies are being funded? What will developing countries have left to barter with for access to vaccines if a pandemic occurs every 5-10 years? abcnews.go.com/Health/covid-1…
If SARS2 emerged from recent spillover from animals into humans, we should be a lot more worried about re-emergence of a similar virus this winter. With SARS1, animal-to-human spillover occurred 2 winters in a row. Thankfully found the intermediate host within a week in Jan 2004.
If SARS2 emerged from pre-circulation in humans for months/years, those still-missing precursors or sibling SARS viruses could also be one step away from adapting into a highly transmissible form, seeding near future outbreaks.
In this sense, I’m not sure why people who are sure that this virus is 100% natural aren’t urging international investigations to find the source of recent spillover/intermediate hosts or pre-circulating human SARS2. Going to SE Asia to find bat CoV SARS2 ancestors doesn’t count.

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More from @Ayjchan

Alina Chan Profile picture
Apr 18
Freedom of speech is important in academia & science but difficult to navigate when it comes to politicized topics.

With #OriginOfCovid, some scientists, journals & reporters have competing interests & may be blamed if research they conducted, funded or glorified caused Covid.
On Tuesday’s hearing, chief editor of Science said the scientific community contributed to politicization of Covid & it was wrong to paint 'lab leak' as a conspiracy theory.

There was widespread consensus, Democrat or Republican, that #OriginOfCovid remains unresolved.
Several representatives asked for forward-facing solutions but none were presented. Today, the media continues to hang onto mistakes & politics of the past.

When confronted, many scientists or journalists who misled their peers & the public on #OriginOfCovid make no apologies.
Read 10 tweets
Alina Chan Profile picture
Apr 11
The @BulletinAtomic Pathogens Project successfully unified experts from opposing ends of #OriginOfCovid, representing diverse disciplines & cultures.

The outcome was a set of practical and high impact recommendations that policymakers are taking note of.
thebulletin.org/2024/04/how-to…
@BulletinAtomic Please see this thread for highlights from the report:
@BulletinAtomic The point of assembling an international task force of experts with truly different view points on #OriginOfCovid and what qualifies as risky research was so that the consensus recommendations would be robust to attacks from angry people on both sides of this issue.
Read 12 tweets
Alina Chan Profile picture
Apr 11
Leaders of scientific funding agencies said Proximal Origin was a nice job. According to the lead author of Proximal Origin, Farrar, Fauci & Collins had advised and led them as they wrote the letter.

So why won't @NatureMedicine put these leaders in the acknowledgements?
Image
The only scientist acknowledged in Proximal Origin arguably contributed much less than these 3 leaders.

He wasn't even at the Feb 1 meeting organized by Farrar where #OriginOfCovid was hotly debated and Proximal Origin was initiated.
Beyond what @Bryce_Nickels pointed out in his letter to @NatureMedicine & International Committee of Medical Journal Editors, the Proximal Origin authors failed to point out that their funder(s) had been involved in the work.
nature.com/nature-portfol…

Image
Image
Read 7 tweets
Alina Chan Profile picture
Mar 19
Serious question:
Is it acceptable for scientists to publish assertions that they know are not well supported by the available evidence?
The first author told Nature they really, really wish they could refute a lab origin but it's just not possible given the data. They were rejected.

They then went to Nature Medicine, telling the editor they would make clear that #OriginOfCovid is natural.
After Proximal Origin is published, the first author continues to worry about lab #OriginOfCovid - citing "definitely concerning work" at the Wuhan Institute of Virology. Image
Read 7 tweets
Alina Chan Profile picture
Mar 18
What I think would be accurate reporting

2020: Some 🧑‍🔬 dismissed lab #OriginOfCovid as implausible/conspiracy theory. Journalists captured. Issue polarized. Mudslinging from both sides.

2021-: FOIA/subpoenas show 🧑‍🔬 went too far, misled journalists. Lab origin plausible/likely.
2024: Some 🧑‍🔬, including those who misled journalists on #OriginOfCovid and engaged in their own repeated harassment of scientists asking for fair investigation, complain to employers about harassment by scientists on side of lab leak.
Even scientists who acted completely professionally and civilly have been silenced on lab #OriginOfCovid and advocating for better biosafety to protect millions or billions of lives from lab-based pandemics.
Read 5 tweets
Alina Chan Profile picture
Mar 16
I believe that reporting on online harassment should be fair.

The latest piece by @jocelynkaiser does not point out the harassment that these dozen scientists filing a complaint have themselves engaged in towards other scientists like myself in the past 4 years.
@jocelynkaiser I would also like to invite the employers of these dozen scientists to review their tweets directed at me and other scientists, and to let us know what their standards for ethical and professional behavior are.
@jocelynkaiser Being a Covid-19 scientist on social media is possibly one of the most stressful social media roles one can have. I've certainly had moments where I lost my cool. And I've been targeted by people holding extreme positions on both sides.
Read 10 tweets

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