What makes you fat and sick VS. What makes you lean and healthy

A short thread about the most powerful levers to look good, feel good and live a long healthy life

There’s a big overlap between the things that make you lean and the thing that affect your health markers
If you take action to look good, a happy “side effect” is that your health markers improve

-insulin resistance
-blood pressure
-inflammation
-testosterone
-cholesterol
Vanity is healthy

Nothing wrong with wanting to look good. But even if you don’t care about how you look, it impacts how you feel.

Get leaner = more energy and libido.

Plenty of mental health benefits such as stress and anxiety reduction.
Longevity

You don’t get chronic disease. While you can’t put your risk of cancer at zero, type 2 diabetes and other metabolic conditions are completely avoidable. And they’re reversible.

You don’t see a lot of overweight people 70-80+ with good quality of life…
Muscle

No, you don’t need to be a bodybuilder. You don’t need to spend multiple hours in the gym. But know that we all lose muscle as we age… unless you’re strategic about it.

You don’t need big bulging biceps. But you want to be relatively muscular.
Cardio

Any exercise is better than no exercise.

The thing about cardio is that it’s inefficient, doesn’t build muscle, and tends to make you hungrier.

If you nail the muscle-building piece… you get the cardiovascular exercise with it
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More from @Mangan150

Jun 25, 2024
Cholesterol is so important for brain health that the brain has its own synthetic machinery for making it.

The brain is only 2% of body weight yet contains as much as 25% of the body's cholesterol. Image
Blood levels of total and LDL cholesterol are lower in Parkinson's disease patients.

Ferritin (iron) levels are higher.

[PMID: 21282940]
Some statins, those that are lipophilic, can penetrate the blood brain barrier.

The effects of these statins has been described as "pleiotropic", meaning they do lots of things; since they lower cholesterol, presumably many of these things are not good. https://doi.org/10.1016/j.bbamem.2020.183340
Read 6 tweets
Mar 24, 2024
Big difference between:

1) Recognizing that most poor food choices contain carbs.

And

2) Claiming that all carbs are “bad”.

I’ve never had a client with a “carb problem” whose carb sources were potatoes, rice or fruit.

The real problem, as I see it, is processed food.
Image
Image
There’s a great lack of nuance on social media.

I am a big proponent of eating animal protein.

And I do think some people thrive on a carnivore or keto diet.

But the idea that everyone should stop eating all carbs forever is deeply flawed...

Undesirable and impractical for most people.

The point is to land on an approach that works for YOU.
As with all things, the devil is in the details.

The appropriate quantity of carbohydrates is going to vary.

Someone on weight loss journey will do better limiting their total carb intake, for example.
Read 4 tweets
Mar 16, 2024
The well-known negative correlation between water hardness and atherosclerotic heart disease can be explained almost entirely by lithium levels. Image
The inverse association of water hardness and cardiovascular disease has been found in many countries. Image
Psychiatric patients taking lithium had massively lower rates of seizures, AML, dementia, and heart attack, compared to psychiatric patients not taking lithium. Image
Read 4 tweets
Mar 4, 2024
How do you know if you're healthy?

Here's my metabolic health scorecard:

1. High blood pressure (without meds)
2. A1C over 5.6% without meds
3. HOMA-IR above 1.4
4. Triglycerides / HDL over 2
5. Overweight or obese BMI
6. High body fat %
7. Waistline > 50% of height Image
High blood pressure without meds:

While there is a genetic component, the root cause of high blood pressure is related to your weight and especially body fat %.
A1C higher than 5.6% without meds:

This one is easy to explain: once you get to an A1C of 5.7% or higher, you get into the pre-diabetic range.

Which is a big red flag.
Read 9 tweets
Feb 26, 2024
Why I never workout for more than 75 minutes per week…

And why you should (probably) train even less than I do.

Here's why: Image
What do I mean by working out?

Let's quickly define exercise:

Exercise is planned, structured, repetitive, and intentional movement.

Its role is to improve or maintain physical fitness.

Walking, tennis, swimming or biking leisurely are "activity", not exercise.
Generally speaking, exercise is "programmed" as either"strength" or "cardio".

We'll see why that's nonsense later in this thread.

For now, let's look at why most strength training routines are not the right tool for most. (They're for powerlifters/bodybuilders).
Read 19 tweets
Dec 15, 2023
Here's how I never workout for more than 75 minutes per week…

And why 99% of people should train even less than I do: Image
First things first, why should you listen to me on this topic?

I'm a 68 year old former microbiologist turned health coach who served 1000+ men and women.

Busy people come to me to get lean, fit & 2X energy in 50 mins/week without going keto, counting calories, or doing cardio. Image
I am NOT saying that you should train for 50-75 minutes per week and then sit on your rear end the rest of the time.

We need to distinguish between exercise (training) and activity.
Read 20 tweets

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