Court has resumed after lunch. Barrister for endocrinologists explains:
For UCL, median age for blockers 14.6, for cross sex hormones 17.4, youngest 10
For Leeds, median age for blockers 16, cross sex hormones 17.2, youngest 12
Of 145 patients referred to Leeds, 38 experienced delays to treatment. On two occasions pressure was seen to be coming from parent and choice not freely made. Barrister says evident there is no immediate access to treatment after referral
Barrister for endocrinologists says the relevant information on risks/benefits is very different for stage 1 (blockers) and 2 (cross sex hormones). ‘It’s no answer to say the majority of patients do go from stage 1 to stage 2.’
Practice is consistent with the guidelines from Endocrine Society. Treating gender dysphoria with puberty blockers has been shown to improve psychological function
Puberty resumes upon stopping treatment with the blocker, it’s said. ‘It is a reversible treatment... there may be side effects, but that does not mean it’s not a reversible treatment’
Judge notes that one of the benefits also cited is that blockers can lead to better physical outcomes. Barrister replies ‘that maybe a side benefit.’ Explains that if young girl takes blockers then there would be less breast tissue to remove later in, should they want to
Another judge questions whether evidence base depends on Dutch study only
Barrister denies assertion that treatment with blockers can lead to inability to orgasm.
During the period of taking the. Blockers, there is an impact on sexual function, but no long term impact.
Same goes for stunted genitalia. While on blocker genitalia does not grow. Once blocker removed from the body, the genitalia continues to grow. There is an issue regarding timing of taking the blocker, my understanding is that in respect to natal makes it may be better...
Not to take the blocker until 14, to allow the penile tissue to grow IF they wants surgery later, says barrister
It is not the view of UCLH that Keira Bell lacked capacity to consent to treatment
Concern of endocrinologists if this claim were to succeed is impact on any other treatments and the involvement with the court. Would this impact on use of blockers in precocious puberty, he asks? ‘This could create a very unhelpful precedent.’
It would be damaging for a child to have to go to court - it’s argued - and that assessment to date is right and the correct way to gain consent.
Some clarifications on earlier points. Of 161 referrals to endocrinology for puberty blockers last year, break down by age is:
10/11 - 3
12 - 13
13 - 10
14 - 24
15 - 45
16 - 51
17/18 - 15
So in fact fewer than a quarter were under 14
Explaining why there has been a delay in publishing results of Early intervention study, Tavistock explains that one author is Russell Viner, president of Royal College of Paediatric and child health. Due to his commitments in the Covid pandemic...
...The team are awaiting his responses to the submissions of peers. Because of the controversy surrounding subject matter, it’s deemed inappropriate to put anything into the public domain until this process has been completed
Barrister for transgender trend now speaking. Concern over increase in the proportion of natal females being referred to GIDS, from around 50% in 2010 to 76% in 2018/19
Transgender trend argues that detrimental effects of cross sex hormones are greater for girls than boys.
It’s argued that defendant must go significantly further in challenging and probing patients, in a constructive way, than currently appears to be the case. Broader cultural factors must feed into the process.
Hyam QC for Bell and Mrs A bow replying
On competency and consent: put headline sign off is “autonomy without comprehension is no autonomy at all.”
Hyam argues that far from resolving the dysphoria, dysphoria persists for those who begin treatment with the blocker and they go onto take cross sex hormones. We have not got away from the v high percentages in the De Vries paper (high 90s).
Hyam says while Butler of UCLH gives a figure of 80% of those on blockers progressing to cross sex hormones, there is also an acknowledgement of loss to follow up.
There is room for the court to separate the exercise of competence from informed consent, Hyam argues. Regarding jurisdiction, it needn’t be court of protection, but rather ‘the court’
Responding to additional evidence from Polly Carmichael, Hyam argues that it is necessary to understand medium and long term consequences when going on the blocker, rather than not requiring a complete understanding.
Hyam says that at one point earlier today it was argued that these children are highly distressed and that there is a risk of Suicide. He argues that there is no evidence of reduced suicide risk with treatment with puberty blockers
Process of gaining of informed consent from these young children is a ‘fairy tale’ he alleges.
Responding to explanation of delay in publication of early intervention, Hyam says he understands point being made about Viner, but you might think it possible to come to court and say how many had gone on to take cross sex hormones. The answer in Dutch study was 100%, he adds
Hyam repeats that claimants position is that whether they be 11 or 17, the child does not have full understanding of puberty blocker treatment, nor understanding of failure to treat. “The suggestion that these very young children are giving informed consent is a fairy tale.”
Anticipated consequence of failure to treat being Desistance, he claims.
Hearing ENDS
Apologies for any typos. Have tried to be as clear as possible and just report what has been said in court
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(🧵) NEW: Today’s news that NHS England has paused new prescriptions of cross-sex hormones for under 18s a) seems a bigger deal than being suggested, b) raises several questions, c) has potentially significant consequences for any forthcoming trial of puberty blockers...
England has - for a period at least - ended the medical transition of children on the NHS. This puts a stop to 20+ years of practice. (The former Tavistock Gender Identity Development Service [GIDS] referred 16 year olds for puberty blockers from around the year 2000.)
The precise trigger for the pause seems unclear. What is the “in-depth review of all available clinical evidence” referred to by NHSE in their statement? I have asked NHSE. NHSE's statement says it was triggered by Dr Hilary Cass’s 2024 major report into children's gender care...
🚨BREAKING: NHS-backed puberty blocker trial PAUSED as regulator raises safety concerns. The Medicines & Healthcare products Regulatory Agency (MHRA) has requested the King’s College trial team amend study protocol, to better reflect risks to children 🧵 assets.publishing.service.gov.uk/media/6998b06d…
Trial team are asked to increase the minimum age of participants to 14 because of fertility concerns.
MHRA explicitly recognises "sterilising effect of puberty blockers followed by cross sex hormones and that gamete retrieval to preserve fertility is not possible at the stage when puberty blockers are given (Tanner stage 2) as neither sperm nor ova have matured."
NEW: I’ve taken a deep dive into the new puberty blockers trial, exploring how we got here, what it will and won’t answers, with a sprinkling of new revelations too.
With contributions from Hilary Cass, trial team members (past & present) and MPs
A former member of the trial told me, “the early planning meetings were unlike any other clinical trial I’ve encountered. We could easily list all the potential harms to monitor and how to test for them, but we didn’t have a clear rationale for giving the drug in the first place”
I can also reveal:
- Close to one in eight children being seen at the London gender hub have disclosed self-medicating with hormones
- NHSE hasn’t started the data linkage study of former Gids patients & has not got the required ethical and regulatory permissions to do so AND…
NEW: Puberty blocker trial for children gets green light, but many questions remain. Sadly, my request to attend a media briefing & put some of them to study leads was turned down on the grounds I’m not a ‘specialist’ health/science journalist. newstatesman.com/politics/2025/…
E.g. Those permitted to join the trial will be considered by clinicians to have “a reasonable prospect of benefit[ting]” from blockers. How will they judge this? Dozens of clinicians from Tavistock GIDS told me it was impossible to tell - that was why some became more cautious.
(They did agree to share the recording of the 1.5 hour event with me several hours afterwards)
COURT CASE Big🧵: I was at High Court today watching Sue Evans v CQC. Psychotherapist & former Tavistock GIDS worker, Evans argues it was ‘irrational’ for the CQC to register private Gender Plus Hormone Clinic (GPHC) & allow it to prescribe (cross-sex) hormones to 16 & 17 yo
Quick note: Gender Plus Healthcare Ltd consists of Kelly Psychology (KP) and GPHC. Owner and director of both is clinical psychologist Dr Aidan Kelly, who worked at Tavistock Gender Identity development Service (gids) 2016 -2021. KP carries our assessments. GPHC is the prescriber
Tom Cross KC (TC) represented Evans and opened proceedings. TC argued that when CQC agreed to register GPHC and see if behaving safely it rightly looked to NHS practice. It judged that GPHC’s practices were “sufficiently aligned” w. NHS. But the situation has subsequently changed
CASE RESUMES: High Court is deciding whether to allow JR by Keira Bell (KB) against Health Secretary (WS) & NHSE in arguing it was "irrational" not to ban cross-sex hormones (CSH) along with puberty blockers (PB). Gov has announced new working group is looking at a pos ban now
Mr Steel for the government is resuming. S argues PB prescribed to v specific groups for specific reasons e.g young children for precocious puberty; adults for certain cancers - so relatively clear division by age group.
Anyone in puberty wld most likely be receiving them for gender dysphoria so easy for pharmacist to tell. This is not case with CSH - used for many reasons, and not so easy to tell why someone might be receiving them. Makes a S.62 order more difficult