can literally anyone be surprised by this?

we knew this all along.

this is why the NIH allowed gilead to change the primary endpoint of this trial 2 weeks before it read out: because it provided no survival benefit and they could see it in the data.…
this drug would have failed a fair trial. they literally changed the rules in the middle and found a subset (recovery) that was, frankly, not that efficacious either, and jammed it through

i'm sure it had nothing do do with the 8 people paid by gilead on the NIH panel for covid
how is that not a massive conflict of interest?

how were these people not recused?

this was an extreme and one might even say outlandish action to take.

it does not appear to have been done with clean hands.

is that how you want your drugs approved?
you can scam and bribe your way through the NIH and FDA, but that does not make the drug work.

many of us were talking about this back in july.

the fix was in on this drug, but that does not make it work.

gilead can hem and haw all they like about "significant heterogeneity" but they failed their own trial too so this seems like PR, not science.

this was just a dishonest attempt to bribe a failed ebola drug into generating some revenue

and what revenue! this is $3000 a patient.
for basically no efficacy

they elbowed it into front line status by cheating.

now they are getting caught.

this has been a flat out scandal from end to end.

i look at A LOT of drug trials and you simply do not see this kind of shenanigans or tolerance for conflict of interest
amazingly, almost no reporters ever wanted to pick up this story (and i know as i shared it with several).

i suspect the coronovirus omerta was just too strong and drug companies are big spenders on ads.

but maybe now it will.

it's ripe and that facts are in.
we need some sunlight here, esp. given the pressure to approve a vaccine on a timeline that is short to the point of being utterly reckless, esp. for an mRNA vaccine (a type not used in humans before)

let's make remdesavir an object lesson, not a dinner bell for misbehavior

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More from @boriquagato

17 Oct
you want to see true bravery and scientific and intellectual integrity?

try this:

ms kuppalli throws down the gauntlet!

and i respond with several sets of data showing mask inefficacy.

her response: block the cat.

could there be a clearer admission that she has no argument? Image

this is the sort of weak rejoinder i think many of us have come to expect from the political arm of team apocalypse. Image
i guess we'll never know just why she recanted all the anti-mask science her much vaunted expertise had taught her and flipped to the opposite position.

you'd think such an "expert" would have clear data and be able to share it.

Read 4 tweets
17 Oct
if there is one thing that galls me, it's the self righteous sanctimony of partisan weather vane "experts" like @KrutikaKuppalli making appeals to their own authority and trying to shame others into silence

but when you pile rank hypocrisy on top of that, it becomes intolerable. Image

she loves to hector others on what an expert she is and expressing that "she knows the science" and you don't.

the issue here is that she's a partisan liar

she agreed with what scott is saying now as recently as march. she said that was science Image
it turns out she used to know the science as recently as february of this year.

scott's science. the actual science.

march really as that flight picture is from march 11. Image
Read 13 tweets
17 Oct
fun thread on the early covid response of andy cuomo. predictably, the facts tell a VERY different story than the big book of fairy tales he just published.

and this does not even get to the horrific policy of forcing cov+ patients into nursing homes then lying about it.
that policy was among the worst in the world. 6 US states did it. they are ~19% of us population. they had 45% of covid deaths. the same thing happened in spain, italy, quebec, and everywhere it was tried.

andrew did it. then he lied about it. then he tried to cover it up.
it was his order. he put his name on it. then, when asked about it, claimed to not know who did it.

then, he changed the way NY state reported nursing home deaths to hide the results of his policy.

this was deliberate and dishonest.
Read 5 tweets
16 Oct
the first rule of economics is that resources are scarce and there are never enough goods or services to meet demand.

the first rule of politics is to ignore the first rule of economics.

so, should any of us be surprised that they ignored all the rules of epidemiology as well?
we have allowed 100 years of pandemic guidelines to be thrown out the window and be replaced with scientifically illiterate grandstanding and demagoguery.

we have elevated fools and charlatans to posts of dictatorial power and turned them loose upon an unsuspecting populace.
they mistook reality (on the right) for the bizarre and improbable tenets of their dated, failed models that had been rapidly repurposed to spread fear and push for budgets once more.

read this whole article, it's wonderful.…
Read 21 tweets
15 Oct
blue states and red states in the US have adopted VERY different courses of action around covid.

i have split states into categories based on voting in last 4 pres elections.

blue, red = all 4

purple = mixed, then split by current governor

no lockdown is a subset of red.
blue states saw a significantly higher rise in unemployment (555 basis points) vs red states (260 basis points) (vs feb column)

current unemployment is 287bp higher in blue states than red.

and the ratio of current unemployment to pre lockdown is 2.73 vs 1.76. (aug rate/feb)
we can normalize this to the feb rate for all states for comparison.

the red states saw less rise and are nearer to recovery.

the purple states actually fared worst early on, but those with red governors are recovering faster.

no lockdown has vastly outperformed.
Read 13 tweets
14 Oct
oh, here's a shocker.

another low information academic is unable to bring any actual facts to bear to support his absurd contention that sweden was a lockdown country and so runs and hides instead.

it's sad what the state of discourse has become at even once top universities.
this is what happens to ideas and ideologues when they live unchallenged in echo chambers.

they grow arrogant, dogmatic, and fragile.

the reason they are all so fond of silencing and censoring those who disagree with them is because their own ideas are so vapid and ill founded.
when you only allow people who agree with you to speak, your ideas undergo no evolution; they face no challenge, no selection

there is nothing against which to sharpen them

ideas with no basis in fact are allowed to survive and take root in these walled cathedrals to groupthink
Read 5 tweets

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