Let's do a deep dive on coronavirus DNA vaccines. This long thread looks closely at DNA vaccines, and will specifically address their potential to edit the human genome. If you make it through, you will be stunned at what you learn, as things are never as they seem.
There are no less than 8 DNA vaccines in development for Coronavirus, including:

ZyCoV-D by Zydus Cadila
AG0301-COVID19 by AnGes Inc
GX-19 by Genexine
INO-4800 by Inovio
bacTRL-Spike by Symvivo
LineaDNA by Takis Biotech
2 more by ImmunityBio and Sanofi

raps.org/news-and-artic…
DNA vaccines have been used in numerous clinical trails back in the late 90's but have never been approved for use among the general public. They have never been perfected, and should be considered experimental.

ncbi.nlm.nih.gov/pmc/articles/P…
DNA vaccines seemed appealing to scientists because of their potential ability to illicit MHC class 1 processed cytotoxic lymphocyte responses, and targeted T-helper, as well as antibody responses.

pubmed.ncbi.nlm.nih.gov/12653868/
Do not confuse the DNA vaccine with the mRNA vaccine (e.g. Moderna 1273). They function very differently. The goal of both is to produce surface proteins on the human cell, but the DNA vaccine adds an extra step. It relies on DNA to transfect the cell nucleus. The mRNA does not.
One may suspect that adding foreign DNA to the nucleus could be risky because it may recombine with your own endogenous DNA. Although the vaccine is not intended to work this way, integration has always been widely acknowledged as a potential serious risk factor.
Let's look at an example of a recent study that attempts to minimize the risk of accidental DNA integration.

mdpi.com/2076-393X/7/2/…
The study states, DNA vaccines did not need to be evaluated by NIH prior to trails, unlike vectors for gene therapy, but that safety studies were used to evaluate possibility of DNA integration into the host genome. As a result, little concern now exists regarding integration.
It goes onto say that risk of integration is no longer a significant concern for DNA vaccines, and that from a regulatory perspective, the vaccine is not considered a gene therapy product. But things are not always as they appear, so let's go deeper.
An earlier 2016 study that actually revolves around a DNA vaccine for MERS coronavirus might provide more insight into the so called "safety studies" that allegedly took place and justify "little concern" for risk of DNA integration into the host.

ncbi.nlm.nih.gov/pmc/articles/P…
We learn that early preclinical studies in animal models raised potential safety concerns that were later adopted by the FDA as guidance for industry when addressing immunogenicity and safety of a DNA delivery platform.
Some of the safety concerns raised include: garnering an understanding of the bio-distribution, persistence, and DNA integration profiles potentially associated with the delivery of any DNA molecule into the nucleus of a mammalian cell.
A further concern is that a vaccine might cause insertional mutagenesis through the activation of oncogenes or the inactivation of tumor suppressor genes.
In addition, a plasmid DNA vaccine could, in theory, result in chromosomal instability through the induction of chromosomal breaks or rearrangements. However, none of these concerns have been witnessed in the preclinical or clinical evaluation of DNA products.
Due to the accumulated success of multiple phase I clinical studies over the last decade, the FDA guidelines have become more relaxed over time.
Caveats in the FDA guidelines include waivers of bio-distribution studies if the “novel gene is inserted into a plasmid vector previously documented to have an acceptable bio-distribution / integration profile”.
Additionally, that “integration studies are warranted only when DNA plasmid persists in any tissue of any animal at levels exceeding 30,000 copies per µg of host DNA by study termination”.
Curiously, the preclinical research studies that established the precedent for assessing bio-distribution / integration profiles were performed more than a decade ago.
The research was prior to initiation of most human clinical trials, and continues to be referenced as the established precedent for a lack of detectable bio-distribution / integration.
Read that again! The research was PRIOR TO INITIATION of most HUMAN clinical trials, and CONTINUES to be referenced as the ESTABLISHED PRECEDENT for a lack of detectable bio-distribution / INTEGRATION.
In light of the numerous DNA vaccine trials in progress, it might be prudent to re-evaluate this question using highly sensitive molecular biology technologies, commonly employed by the gene therapy field, to profile the human genome for putative sites of insertional mutagenesis.
I'm not making this up. It's stated in the 2016 study, which clearly uncovers a very serious underlying safety concern involving FDA protocol, as it pertains to DNA vaccines and their potential to integrate into the human genome.
Upon first glance, it does appear that scientists are confident in the DNA vaccine, and that insertion into the host genome has been ruled out. But upon further investigation we find this is not the case, since test methodologies are outdated, yet the old paradigm persists.

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More from @science_cited

15 Aug
A 2006 case study looked at the autopsy of a 3 month old female infant who died suddenly after receiving a hexavalent vaccine. After autopsy, damage was observed on the brain stem of the child, specifically the bilateral hypoplasia. (PMID 16231176)

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Bilateral hypoplasia meaning atrophy on both sides due to destruction of some of the elements and not merely to their general reduction in size. More specifically, the brain stem damage was located at the arcuate nucleus.

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The arcuate nucleus is a group of neurons located at the base of the medial plane in the hypothalamus. This cluster of neurons is responsible for regulation of heartbeat. Both pressor and depressor responses can be elicited by the chemical stimulation. (PMID 23260431)

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Read 5 tweets
14 Aug
MANDATORY VACCINE IMPLEMENTATION

My intent here is not to be morbid or to fear monger. I am simply being realistic. After almost 8 months, the final pieces of the puzzle have fallen into place. Here is how I believe mandatory vaccines will be logistically implemented in the U.S.
First we must understand mask mandates. Their purpose is basically 4 fold.

1.       Dry run (practice run) - This allows the kinks to be worked out ahead of time, for the wet run.

2.       Conditioning – It’s very important to train people and get them used to obeying orders.
3.       Bait and switch – The media will claim masks are neither healthy nor safe, to nudge people towards the vaccine alternative. You may only remove your mask if you agree to vaccinate, they will say.
Read 9 tweets
12 Jul
My Coronavirus Vaccine Predictions:

1. Trump will not directly mandate the vaccine, but won't stop it either.

2. Mandates will come at state level. If you're in CA or NY, get out now! All states will jump on the bandwagon eventually.

More>
3. There will be multiple Coronavirus vaccines that make it to market around 2021, including the Moderna 1273.

4. Those who exert sufficient effort can avoid mandates. However, you will be cast out of society and may need to learn micro farming.

More>
5. The private sector will quickly adopt vaccine mandates for both employees and customers. Eventually you may be prohibited from shopping at some stores without proof of vaccination.

6. Mandates come in waves, not all at once. First, targeted cohorts but will expand.

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Read 4 tweets
29 Jun
One of the biggest scams in history is the concept and implementation of so called "Public Health".

Vaccines are actually a sub-scam falling under the greater umbrella of the great public health scam.

Read this thread on the rational behind public health.
There is no such thing as collective health. Only individual health.

The concept of collective (or public) health is an abstract idea. It is not tangible and can be no greater than the sum of its parts, which are the individuals within a given population.
However, by grouping you into this collective, society can rationalize away individual sacrifices.

These sacrifices often manifest in the form of sacrificial killings carried out in the name of the so called "Greater Good".
Read 10 tweets
10 May
Many wonder why it makes sense to vaccinate a newborn for a sexually transmitted disease. Ask a doctor, and they will likely argue that vaccination can protect the child from disease with mothers testing positive for hepatitis B. But is this really the case?
CDC guidelines recommend that mothers should be tested for hepatitis B antigen in early pregnancy, and that infants born to mothers testing positive should receive vaccination.

cdc.gov/mmwr/preview/m…
This raises a serious issue because mothers suffering from acute infection will develop antibodies that are transferred across the placenta to the fetus. A mother testing positive in early pregnancy can develop antibodies prior to giving birth.

publichealthlab.ca/reportingname/…
Read 10 tweets
17 Jan
"The Fire of Pharma"

(1 of 6) School vaccine exemptions are fuel for the Fire of Pharma. A slow, controlled, incremental, strategically planned burn (state by state) is key.
(2 of 6) The law of diminishing returns has been carefully considered. If too many states are targeted simultaneously for removal of exemptions, the fire would quickly grow out of hand.
(3 of 6) Consider phase one complete after the brush has been cleared and primary fuel sources depleted. This occurs when all states have suffered loss of school exemptions (or have enacted laws to protect them).
Read 6 tweets

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