@earnestobob @MLevitt_NP2013 This isn’t as big a surprise as I’m sensing. If you’ve seen a related immunogen, you’ll have T-cells responsive to epitopes (short peptides) in common between the old immunogen & a new but related one. Several papers have proven this occurred between common cold causing CoVs &
@earnestobob @MLevitt_NP2013 ...SARS-CoV-2. I confess I haven’t explored the corollary on the antibody side but in principle the same could apply. I haven’t looked because it’s the T-cells that dominate responses to most viruses & respiratory viruses. On T-cells I’m aware of at least 7 full papers showing...
@earnestobob @MLevitt_NP2013 ...very substantial immunity (T-cell responses) to SARS-CoV-2 in prepandemic leukocytes.
A recent paper showed 81% of subjects having this distinct recognition. Again, epitope analysis demonstrated the shared origins as common cold coronaviruses. I mused that if there’d been...
@earnestobob @MLevitt_NP2013 ...just a little more prior immunity, there’d have been no pandemic at all, as in some countries.
In U.K. I’ve revised my estimate of prior immunity up from 30% to 50%. However, I’ve revised down by estimate of nos infected & now immune by half to 16% (acknowledging that I’d...
@earnestobob @MLevitt_NP2013 ...used too low an IFR, a global value, for an older pop like U.K.). The effect is that community (aka herd) immunity has long been in place in U.K., no later than June. That’s what makes the claims of 30,000+ new cases per day implausible. Error prone mass PCR testing is...
@earnestobob @MLevitt_NP2013 ...much fear, suffering & avoidable deaths in our country. Govts admission in Hansard that it doesn’t know the operational false positive rate is something I’d never see admitted, mostly because I hoped it wasn’t true. I’m devastated to learn people are willing to continue...
@earnestobob @MLevitt_NP2013 ...to permit use of this test, knowing it’s outside any normal controls. We wouldn’t run an NHS diagnostic without these basic checks, because we wouldn’t be able to say what being positive means. But it is an NHS diagnostic.

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More from @MichaelYeadon3

17 Nov
Thanks JE! Up to date info, total weekly deaths, which are very close to normal for early Nov. I say again: you can’t have a lethal pandemic stalking the land yet not have excess weekly deaths. The explanation: we’re in a PCR false positive pseudo-epidemic. If anyone wants to...
...do battle & claim there are excess deaths, once adjusted for population change, there’s little to nothing. And can’t you think of an explanation that isn’t covid19? Restricting access to NHS for a population for 8mo & counting will lead to avoidable non covid19 deaths. This..
...pandemic was over in June or earlier, due to herd immunity, reached quickly because half of us already had prior immunity. We’d been infected by common cold causing coronaviruses, so cross immunity, like cowpox/smallpox & the very invention of vaccines.
Everyone surviving...
Read 7 tweets
15 Nov
Were MPs given full information about claimed (unusual) stresses on the NHS before the vote on LD#2?
ICU loadings weren’t unusual for time of year (as I told you, 81%. Turns out it was 79%). MPs not told.
Oxygen use entirely normal. MPs not told.
No excess deaths. MPs not told. Image
Crucial adjustment to deaths data: adjustment for population. Thanks TheStatsGuy. So not only no excess respiratory deaths which I’d been flamed for (correct,but MPs not told) but with this view, no excess deaths at all. But we’ve had thousands of covid19 deaths recent weeks. Image
The resolution is thousands of normal deaths (620,000 each year in U.K.) are wrongly coded Covid19 to scare you. That happens because the pitifully poor mass PCR test generates immunologically unfeasible nos of positive results. Meaningless without the operational FPR. Govt...
Read 4 tweets
14 Nov
I demand we halt mass PCR testing. Everyone should campaign for this. It’s the single action needed to save our society.
1. It’s untrustworthy. Govt admits it’s out of control: basic QC hasn’t been done, ever. If was a diagnostic test in the NHS, it would immediately be stopped.
2. It’s not necessary. Track, trace & isolate might once have been useful but it’s proven to be a hopeless flop. It finds few contacts & far too late. Only a small minority of contacts are reacted. Of those contacts, 90% don’t do what was asked of them. It helps no one.
3. It only causes damage. Because of a positive test, almost all of which now aren’t of live virus, it damages lives & livelihoods for no gains. “Cases” aren’t true but drive lethally bad adaptations like restrictions to NHS, leading to excess deaths.
Read 10 tweets
13 Nov
@elonmusk Elon, there isn’t one answer to this. It depends among other things on the number of tests run per day as a measure of stress on the testing system. Most false positives arise from handling errors in the sample processing stages. In U.K. I’ve seen test runs yield >10% positives.
@elonmusk This is on people who weren’t symptomatic. I’m happy to be corrected, but I don’t think we ever got to 10% positivity in the population at the height of the spring pandemic.
If correct, it’s then certain that such PCR runs are completely unreliable.
@elonmusk I’m a scientist & love cool techniques like PCR which can do things that are almost impossible in other ways. But features giving PCR awesome powers also make is non-robust in a production context. For some reason, too few are aware it’s possible to have all positives be false.
Read 16 tweets
12 Nov
@chicago_sunrise @subsix848 @AlexBerenson @JAMA_current Strictly you can’t culture (grow in isolation) a virus. They only grow if they can invade living cells. So that’s what we mean: “can you infect susceptible cells using a clinical sample?”
In this paper, the answer is no, in patients whose PCR was only positive if amplification...
@chicago_sunrise @subsix848 @AlexBerenson @JAMA_current ...is turned up high. If other words, if your sample is PCR positive only when amplification is turned up beyond 32 cycles, THEY ARE NOT INFECTIOUS.
Once we learned this, early in the spring outbreak, I bet you all think there was broad agreement that we’d set the maximum...
@chicago_sunrise @subsix848 @AlexBerenson @JAMA_current ...amplification to 32 cycles, if you’d hope so, if there were any honest scientists doing this work.

They did no such thing. In U.K. they’ve kept the amplification turned up to FORTY (40) cycles, even AFTER it’d be repeatedly shown that positive results obtained at more than...
Read 11 tweets
10 Nov
@d_spiegel @LettingFocus @SeanBFlanagan @BreesAnna @toadmeister @allisonpearson @ClarkeMicah @Charlotte3003G @MLevitt_NP2013 @SunetraGupta @carlheneghan @MartinKulldorff @AlistairHaimes @FatEmperor @HaraldofW @JuliaHB1 @Iromg @talkRADIO @mgmgomes1 @spectator @unherd @freddiesayers @spikedonline @ProfKarolSikora @HuwMerriman Respectfully, that’s incorrect, Sir David. I bow to you as master statistician. I ask that you recognise there is a great deal of laboratory insight I have that affects the outcome & isn’t amenable to statistical analysis if you’re unaware of these.
Just as a simple example...
@d_spiegel @LettingFocus @SeanBFlanagan @BreesAnna @toadmeister @allisonpearson @ClarkeMicah @Charlotte3003G @MLevitt_NP2013 @SunetraGupta @carlheneghan @MartinKulldorff @AlistairHaimes @FatEmperor @HaraldofW @JuliaHB1 @Iromg @talkRADIO @mgmgomes1 @spectator @unherd @freddiesayers @spikedonline @ProfKarolSikora @HuwMerriman ...the manufacturer’s values for false positives is under ideal conditions & measure the intrinsic limits for example the ability under perfect conditions to distinguish some sequences from all others. This isn’t the main source of false positives at all. These are mostly...
@d_spiegel @LettingFocus @SeanBFlanagan @BreesAnna @toadmeister @allisonpearson @ClarkeMicah @Charlotte3003G @MLevitt_NP2013 @SunetraGupta @carlheneghan @MartinKulldorff @AlistairHaimes @FatEmperor @HaraldofW @JuliaHB1 @Iromg @talkRADIO @mgmgomes1 @spectator @unherd @freddiesayers @spikedonline @ProfKarolSikora @HuwMerriman <lost my place & fell asleep, it’d been a long day>
...caused by issues related to the sample itself (eg biologically they’re very ‘dirty’ & may contain very large amounts of irrelevant bacterial DNA) and / or sample preparation. I use as explainer the comparison of the person...
Read 24 tweets

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