Ben B Profile picture
24 Nov, 10 tweets, 2 min read
Linked thread is great but let me try to breakdown into laymen’s terms why Niacin seems to be a very very good Chinese plague treatment.
Niacin lowers serum free fatty acids. Or in other words, purges the bad (PUFA) fats from your blood.

This is important because one of the cardinal indicators that a patient has increased Covid mortality risk is hyper-ferritinemia - too much iron in the blood.
Patients who don’t survive have iron levels that are twice as high as that of survivors.

Paper here describing hyper-ferritemia as a hallmark trait of Covid mortality: thelancet.com/journals/lance…
Where this ties into serum free fatty acids and Niacin is that iron is highly reactive with polyunsaturated fatty acids (PUFA). High PUFA in the bloodstream causes the iron to oxidize - essentially creating rust in the blood. This increases inflammation and clotting.
A big driver of respiratory symptoms are the microclots that form in the capillaries where oxygen/co2 interchange takes place. Larger clots also pose a significant threat of heart attack or pulmonary embolism.
By lowering PUFA levels in the blood, Niacin may reduce the oxidative stress and other issues caused by hyper-ferritinemia. This is why I have recommended aspirin, as it does something similar in lowering serum PUFA. But niacin can be taken in higher levels without side effects.
Niacin also lowers blood pressure (top Covid comorbidity) by acting as a vasodilator. It’s why niacin can cause flushing. Incidentally, you don’t want to take non-flush niacin. It’s useless.
No-flush niacin doesn't contain either nicotinic acid or nicotinamide. Instead, it contains inositol hexaniacinate. In theory, the body should slowly convert this into nicotinic acid, but in reality it doesn’t.
Combustion of nicotine (cigarette smoking) generates nicotinic acid (niacin) so that’s probably why smokers have counterintuitively had lower mortality rates. I like white teeth though so I’ll just take the no-flush niacin.
Nicotinic acid is the form of niacin you want. It’s the most potent in lowering serum PUFA and the only one that gives you vasodilation. Just suck it up and embrace the flush.

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More from @GraduatedBen

22 Nov
Like I said wayyy back...lockdowns (when used at all) should have been tailored to high-risk (sick and older) Americans. This ideological insistence on treating everyone exactly the same is deranged and debunked.
EQuALitY means having the exact same guidelines for a healthy teenager as you would for an 80 year old. The cost-benefit calculation here is wildly sensitive to factors like age and pre-existing conditions and not taking that into account has been a massive policy failure.
It also means that you drag out the timeline and expose the elderly to greater risk. Rapid acquisition of post-infection immunity by the lower-risk would have reduced the number of carriers posing a threat to the high-risk.
Read 4 tweets
22 Nov
Trump needs to send in lawyers who are SHARKS. I have great respect for Giuliani, Powell, others, but they aren’t appellate lawyers. This isn’t a case for defense attorneys and former prosecutors - SCOTUS can only consider arguments presented, not make the arguments for us.
We need lawyers with strong appellate records who know relevant election caselaw. @tedcruz and @LindseyGrahamSC and other Judicial committee lions should be involved here. We need 2000s style Brooks Brothers clad lawchads.
The lower court filings need to be solid - it’s hard to introduce new evidence at SCOTUS level. Lin Wood got a settlement in a libel case. Cool. What’s his track record in election law (other than messing up our Michigan filing)? Has Jenna Ellis ever argued before Supreme Court?
Read 5 tweets

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