Siddhartha Mukherjee Profile picture
Dec 21, 2020 6 tweets 1 min read Read on X
1/2 OK, let's move the challenge. I'm a good cook. Shamelessly good (mostly Asian). If you agree to donate $20 to a local food bank or charity, I'll post our family dinner recipes every night. I'll donate as well until Chistmas (I'm not religious but it's a date)
2/n Tonight I made hotpot. Boiled water, added soy sauce, chillies, SLUG of Miso and Chinese Szechuan Chili Crisp. Cut Tofu, mushrooms, cabbage, carrots, pork slices, scallions, noodles. Everyone had a bowl and had hot pot...
That’s the end of the hotpot Image
Ok. South Indian style chicken curry with Padma Lakshmi spices. You'll need: skin on chicken (red meat), garam masala (figure it out), tumeric, green cardamom (optional), green/ red chillies, coconut milk, cumin, dry coriander, full fat yoghurt, oil, two onions,potatoes.
But I need a promise of two things. $20 to a food bank. And organic chicken, with skin on, red meat, and chillies of any kind. I'm a big improviser, so you can skip many things. But cumin and coriander and onions are essential.
If you want vegetarian option, substitute cauliflower for chicken. Same difference.

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More from @DrSidMukherjee

Dec 30, 2021
1/n May I propose a solution to this standoff? Maybe for every peer-reviewed article in a widely read publication (Nature etc.) there should be an online commentary by a historian, sociologist, anthropologist
scientificamerican.com/article/the-co…
2/n I did not understand some things about this piece (my fault). No one that I know extrapolates from ants to humans. But to demolish the entire field of behavioral genetics as "racist" seems an equal and opposite sin
scientificamerican.com/article/the-co…
3/n And so a commentary AND CRITIQUE from a historian, anthropologist etc. on a paper might help. There's no dearth of online space, and assigning such a critique might equalize the weighing scale of authority of any one piece.
Read 5 tweets
Dec 20, 2021
1/n So, here's our latest work in PNAS. pnas.org/content/119/1/…
2/n The mystery begins because mutations in splicing factors (SF3b1) cause a blood disease called Myelodysplasia.
3/n But what could splicing have to do with MDS ? Previously, we published a paper in which we made 7 blood-like cell lines, using Crispr, which were ONLY different in possessing the mutation (or not).
Read 7 tweets
Jun 14, 2021
1/n It might be an interesting idea to create a SUBGROUP of researchers to study the B1617 (Delta) SARS-Cov2 variant that dominated the Indian wave of the pandemic and caused such enormous lethality
2/n What do we know about the "real world" effectiveness of the current vaccines against this variant? How many fully vaccinated people got SARS-C2-Delta after being fully vaccinated?
3/n Do vaccinated people (which vaccine?) have milder disease and fewer deaths/hospitalizations?
Read 5 tweets
May 3, 2021
1/n The anecdotal stories about the number of people in India getting COVID after AZ or Covaxin need to be addressed.
2/n Either it’s a question of the denominator. Even with 90 percent effectiveness, 10 percent breakthrough in a country of 1.3 billion is a HUGE number. So maybe the anecdotes are that 10 percent
3/n Or the true effectiveness of the vaccines in the field are substantially lower. In which case, we need to measure that... it’s crucial to drive policy
Read 21 tweets
Apr 25, 2021
1/n Long thread, but of crucial importance. The COVID-19 situation in India is as dire as can be. And it is not just THEIR problem, as long as virus circulates in the world, it becomes EVERYONE'S problem. We live in a global society; viruses don't respect national borders.
2/n This is, or was, a moment of historic importance for the US/ Biden administration to show leadership and solidarity. Recall the legacy of WW2 that established America as a world leader. Compare that to the leadership today.
3/n Now, let's get practical. I've spoken to several people on the ground in India, and here are the immediate needs in terms of priorities. Several field hospitals are being set up, but there are dire infrastructural needs.
Read 7 tweets
Jan 12, 2021
1/n Please pay attention, please. I'm afraid that we are falling behind in this COVID race. There are at least 4 variants of concern: variants arising in London, Manaus, Japan and South Africa.
2/n The London variant is more contagious. The Manaus and South African variants may -- MAY -- cause repeat infections.
3/n I cannot see any way forward except: 1. detect the frequency of the variants in the USA and isolate and confine them.
Read 7 tweets

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