Is $RFL the next Jonas StraightPath-like home run? Two cancer drugs in expedited-FDA-review status for a Q1 decision. Market size for Pancreatic approval alone could 10x the stock. 65%-approval chance each (FDA stats.) More Jonas magic possible? Or could be nothing....
$RFL$22/sh now. $200-$3,000 possible
- if Pancreatic drug approved this quarter (65% odds) & likely becomes standard of care.
- A typical Jonas set up. (I recall Net2phone $ Straightpath.)
With two fast-tracked drugs for FDA approval, 65% chance each this quarter, the EV on this one seems off-the-chart $RFL
This informative VIC write up makes a good case for a $200-$3,000 $RFL stock range. Though my calcs are more conservative. valueinvestorsclub.com/idea/RAFAEL_HO…
And the othe hire is a CCO - Chief Commercial Officer, A.K.A Head of Sales
Why hire a Sales VP when nothing to sell? And why would one like that take the job?
$RFL
"Devimistat, by Rafael, and Masiviera, by AB Science, will be lead candidates in the first-line from a clinical and commercial standpoint." #RFLexpresspharma.in/latest-updates…
Looks like the new $RFL CEO got 5% of he company in RSUs. Some dilution, or a heck of an incentive to raise the stock price.
“The Company’s Board of Directors....approved the Employment Agreement with Mr. Mallik, which provides......(iv) an initial grant of restricted shares of the Company’s Class B common stock representing 5% of the total outstanding shares of the Company...”
“Overall response rate (ORR) was 50%, comprised of 26 participants with a complete remission (CR) and 5 with a CR with incomplete hematologic recovery (CRi)... Historically, investigators said, only 33% of older patients reach a CR/CRi.” Seems meaningful?
But would it be enough to achieve a “standard of care” status for AML?
$RFL files a $250m shelf registration. Soon after a CEO hire. FDA approval & thus commercialization start imminent? Or am I misinterpreting? sec.gov/Archives/edgar…
$250m is a massive amount vs. $RFLs previously tiny burn. The only reason would need (+a high-powered CEO & Sales VP) is full scale commercialization, IMHO.
No reaction to this giant “shelf” $RFL just filed. Same as w CEO/VP Sales hires just earlier. Efficient market, I guess.
What are the odds $RFL could dwarf Straightpath?
“4 confirmed CRs out 27 (Pancreatic) patients in the Compassionate Use Program.”?
So far, darn impressive. $RFL
$RFL upside from here appears 10x-40x 👀with good odds & not too distant future. Not cancer-treatment advice
Why $RFL up today? Don’t see anyth new in the Q3 earnings. But why not?
Last year, an NCBI article profiled $RFL ’s CPI-613 as “2nd most promising Pancreatic Phase3 trial”.
50k patients in USA (3x WW) x ~$100k/yr (?)/ treatment?
And WTH is Altira Capital & Consulting, LLC whose remaining interest $RFL is buying out?
Interesting that Jonas/ $RFL been buying out Altria’s tiny CPI-613 royalty share at $3b-equivalent valuation for a few quarters now. HT @boskovic64
Reminds me of Straightpath days when Jonas was adding small licences at hundreds-$$mill total-spectrum valuation which later probed worth billions. $rfl
$RFL. A single non-toxic compound to enhance chemo effectiveness across most cancers. Quite a position to aim for. A big-pharma kind. (Reminds Amgen - a $100b co build on essentially a single purpose compound.)
Every step taken recently screams “commercialization in 2022”. The new CEO and Sales VP must have seen convincing Ph3 data, or why take the “nonexistent” job?
Breaking: $RFL raised from "Underweight" to "Non-Futile".
Big reveal at Rubicon-Suchs:
Upgrading $RFL from “Non-Futile” to “Massive”
Doing so in off-trading hours so as not to spike the price.
Admitedly, slackers at Rubicon-Suchs™️ msy not have done extensive research, but CEO Ameet Mallik surely has. And whose judgement do you trust on cancer drugs?
Analysts at Rubicon-Suchs ™️maybe slackers, but they are not dumb. (Or are they?)
The head of Novartis US Oncology jumps his prestigious job to head up a “real estate” company for a “nothing” salary and a 5% share in RSUs😱 😱 Holy oncology!
But there is more....the head of Sales & Commercial Operations at Immunomedics - a $21b-valued Cancer company also quits a cushy job to join same unknown "real estate" company to head Sales & Operations - areas which literally don't exist? Mamma malignia!
What are these people smoking? Or did they just inhale CPI-613 and messed up their selfish-gene Mitochondria??
Why should $RFL rise daily for weeks by high single digits 🤷♂️?
So $RFL pancreatic-trial’s end point quietly switched late June from original “PFS” to a higher-standard “OS” - the reason readout date moved to Q4. But why we find out in a roundabout way and not communicated?
Good descriptions also of earlier trials successes,
When in doubt, bet with the billionaire owner? $RFL
I wonder. Of all his businesses, where is Jonas spending the most time/effort? $RFL $IDT
Jonas’ other unicorm - Straightpath:
- Spunoff @ $5/share in 2013
- Reached $40 in 2015
- Attacked by a short to $8 in 2015
- Reached $36 again in 2017
- Bid by ATT for $85
- Acquired by Verizon for $185 in 2018
$RFL
$RFL on the other hand:
- Spunoff at $9 in 2018
- Reached $29 in 2019
- Crashed to $12 in 2020
- Reached $62 in 2021
- Future awaits......
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$APEI seems interesting. A promising turnaround @ 7x FCF expectations this year, & one insider loading $11m-worth of shares in the past two weeks.
$APEI Q2 wasn't that great, but still very nice YOY EBITDA gains.
On the other hand, the valuation is half its pre (disastrous) 2021 Rassmussen acquisition, and is now valued less than the Rassmussen purchase alone. 👀👀
If turn Rassmussen to even modest profitability, current FCF can nearly double. And even now, $APEI is just a 7x multiple with Rassmussen losses. Rassmussen eventual profitability, IMHO, is a very realistic (but obviously not guaranteed) scenario.
Anybody likes (Valeura) here? After the original amazing multibag, the winners seem to have moved on. But the story seems far from over.VLE.TO
You have an oiler at 1.4x FCF sitting on likely 10yrs worth of reserves formally classified as “3yrs”, in a friendly jurisdiction, and the CEO whose stated aim is to quadruple production in 2 years. 🤷♂️🤷♂️
This is not counting a possibly-imminent tax deal that should add ~$100m worth of value to the balance sheet or ~1/4 of the current MC. $VLE.TO.
Can’t remember. Did I mention $trmr is 6x this year’s guided fcf, “at least” 20% growth, and MC has 40% cash?
“Our strong balance sheet profitability and cash flow will enable us to maintain continued growth both organically and through potential M&A, while adding value for our shareholders through the $75 million share buyback we announced today”
“We believe this (53% EBITDA) margin represents the best-in-class for our industry.”
$TRMR is hypergrowth at unreasonably-low-price? #TRMR
Future looks bright, though past, a bit murky. Adtech, esp CTV/vid is on fire. Better numbers at far lower val than comps. A no-brainer with hair? $trmr #trmr
Many great threads & insights on fintwit, esp by @Yield_Fanatic Me, I am just trying to avoid overthinking great numbers. $trmr #trmr