2. Interesting to hear HHS secretary Alex Azar blame the states for being too slow in the rollout of vaccine when states are still waiting for money to do the work. "States have ample funding," he said... including $3B that's still coming.
3. Azar says 2 weeks from now — when he won't be HHS secretary — states that are using vaccine most quickly will get more vaccine. Incentive system. You want more vaccine? Get it into arms quickly.
But he won't be HHS secretary in 2 weeks.
4. CDC Director Robert Redfield — who won't be CDC director in 2 weeks, when this new incentive program goes into effect — is asking governors to expand vaccine to all individuals 65 & older & people with a comorbidity who have medical documentation.
That's a lot of people.
5. CDC director Redfield, who signed off on the CDC prioritization recommendations that he & Azar are now asking states not to follow, warns it's going to be a rough January, but there's light at the end of the tunnel.
6. General Perna really likes the word cadence.
7. General Perna, OWS head, says 70,000 nursing homes are enrolled in the CVS-Walgreen program. 11,000 have received first doses.
8. General Perna says he feels confident that the flow of #Covid19 vaccine from the manufacturers is such now that "we can open up the aperture."
Pharmacies seem to be a big part of this increase.
9. Azar says the CDC's priority recommendations for who to vaccinate in what order "aren't meant to be prescriptive."
10. CDC Director Robert Redfield says CDC is doing a "deep dive" to look at how states are doing distributing #Covid19 vaccine.
11. Secretary Azar says the freeing up of 2nd doses that are being held back should not lead to a need to stretch out the intervals between vaccine doses — 21 days for the Pfizer vax, 28 days for the Moderna.
12. Azar says if, God forbid, there are problems with the flow of vaccine from Pfizer or Moderna, new doses will be prioritized to people needing 2nd doses.
13. Azar explains that in 2 weeks time, states that aren't using their supplies quickly enough will get fewer doses — distribution won't be simply by population.
Asked if the Biden administration, which will be in power in 2 wks time, agrees, Azar says there's 1 govt at a time.
13. OWS co-chair Moncef Slaoui says the Moderna trial trying to test the vaccine in teens aged 12-18 is having a v/ hard time enrolling participants. In 4 weeks, they've enrolled only 800; they need 3,000. Need data to get an FDA clearance to use the vaccine in <18 yr olds.
14. Slaoui projects J&J may be able to apply for an EUA for their 1 dose vaccine — if it's sufficiently protective — at the end of Jan. If it gets an EUA, small amounts of the J&J vax would be available in Feb., more in March. But sounds like it will be April before lots is avail
15. Slaoui says AstraZeneca maybe in a position to apply for an EUA for its 2 dose vaccine in early March; Novavax may be in a position to apply in late March, early April.
end thread

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More from @HelenBranswell

5 Jan
1. Going to turn this into a short thread from today's @WHO press update.
2. @DrTedros says that 30 countries have already started to vaccinate against #covid19.
That is truly extraordinary. The first anniversary of the sharing of the genetic sequence of the SARS-CoV-2 virus is still a few days away.
3. @WHO's panel of vaccine experts, The SAGE, met to provide advice on the use of the Pfizer-BioNTech #Covid19 vaccine, for which WHO issued an emergency use listing (EUL) last week. Their recommendations are coming in a few minutes, I'm guessing.
Read 8 tweets
5 Jan
1. A #Flu thread:
Because Friday was a holiday, @CDCgov published FluView today.
US #flu activity remains super low, thankfully.
So far this season a single child has died from flu. It's early & peds deaths generally come later in the season, but there are often more by now. Image
2. So far in the 2020-21 #flu season, the US has recorded 877 positive flu tests, out of more than 360,000 conducted. That is amazingly low. Image
3. This FluView graph gives you a sense of this #flu season versus multiple recent flu seasons. Pretty much nothing compares. The closest season was 2015-16, the orange line in the graph, which was crazy late and very mild. You'll want to refer to this when you read tweet 4. Image
Read 6 tweets
30 Dec 20
2. Emily Travanty, scientific director, Colorado Dept of Public Health and Environment Laboratory, says the lab is working on a 2nd possible variant isolate.
Both people are national guard personnel who've been working at a nursing home that is having an outbreak. So, more.
3. Colorado state epidemiologist Rachel Herlihy says neither of these individuals has traveled internationally in recent weeks. 2 theories: They were infected at the nursing home or elsewhere. Investigation underway at the nursing home.
Read 5 tweets
30 Dec 20
1. It's a real pity the UK drug regulator, MHRA, doesn't hold public advisory committee meetings to assess #Covid vaccines, in the way @US_FDA does. Would have been fascinating to listen to a detailed analysis of the AstraZeneca-Oxford vaccine's emergency use application.
Thread
2. The vaccine is a critical part of the global #Covid vaccination strategy. Oxford's goal was to make a vaccine manufacturers around the world could make cheaply; they're to be highly commended. The project, though, has suffered from serious missteps. wsj.com/articles/astra…
3. Today the UK regulator approved the AZ-Ox vaccine for use in Britain. It's estimated to be about 70% effective, but the confidence intervals on that are wider than those for the Pfizer & Moderna vaccines. It works, but how well exactly is still a bit unclear.
Read 8 tweets
28 Dec 20
1. FluView, @CDCgov's weekly #flu report, went up today. It was for the week ending Dec. 19. Remarkably little flu to be found in the U.S.
People are being tested for it — more than 300K tests to date this season. But so far, only 720 positive tests.
Thread.
2. Things could change, #flu wise. But so far, this is looking like a non-season. Note the orange line, though -- the 2015-2016 season started remarkably late, only going above the epidemic threshold (dotted line) in late January-early February.
3. So far this #flu season there has only been a single child who has died from flu. A blessing.
Read 4 tweets
20 Dec 20
1. I am listening to #ACIP again today & will tweet about the discussion today about who should be next in line for vaccine after health care workers & nursing home residents & staff.
Tough choices ahead, Nancy Messonnier of @CDCgov tells the committee as it starts its day.
2. @DrNancyM_CDC tells #ACIP that it is currently anticipated that there will be enough vaccine to vaccinate 20M people in Dec, 30M in January and 50M in February.
3. Anyone who wants to watch the #ACIP meeting can find it here: ustream.tv/channel/VWBXKB…
Read 24 tweets

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