Well didn’t take too long until he posted this smh πŸ€¦β€β™‚οΈ lol.. His worldview is so focused on prescription opioids being the main catalyst for addiction that he will admit that our record lows of rx opioid prescribing is not low enough smh.. He really can’t connect the dots Image
with Rx opioid prescribing down at record lows and OD deaths still climbing.. It never occurred to him to analyze what drugs are actually causing the overdose deaths.. He then argues that deaths were also soaring when people were using heroin etc when rx prescribing was also high
What he fails to realize is that we have had data describing increase in overdose deaths decades before the mid 90s high prescribing and the fiasco with Purdue Pharma and OxyContin... Once again to only focus on prescription opioids is to miss so many other variables at play
In overdose deaths (prior psychiatric history, socioeconomic factors, diversion, misuse of prescription opioids, poly substance overdose deaths, etc) his fixiation on rx opioids and decreasing the supply will not work in decreasing overdose deaths.. what we need is to fix the
Structural issues. We need to decriminalize drugs, we need robust harm reduction solutions, etc.. until those serious ideas are actually put on the table just focusing on decreasing drug supply will not fix anything regarding ODs.. #TwitteRx
And now the very thing he said not to do he did with this reply smh.. Just because A increased alongside B doesn't mean one caused the other.. Image
Im turning this into a debunk Kolodny thread lol... I will add anymore screenshots i see on his page and explain why its wrong..

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More from @GhanaboyPharmd

4 Feb
After listening to NPRs new podcast episode with kolodny and others on How to fight the opioid epidemic I came across many things that were problematic but the two issues that stuck out to me I will highlight below...
The 1st issue I had was kolodny’s narrow view of addiction.. Throughout the episode we heard tragic stories of people succumbing to addiction and dying of overdose.. In these stories we heard how they suffered with substance abuse issues, psychiatric issues, also people with
Socioeconomic issues as well.. Instead of discussing all these factors and how they can attribute to why someone can succumb to addiction kolodny wanted to focus on 1 thing being the main catalyst: Prescription opioids.. Dr. Carl Hart who is a neuroscientist has been doing some
Read 12 tweets
11 Jun 20

Sickle cell disease will always be a disease that means so much to me.. Growing up seeing my brother battle with this disease was hard. Many nights my family would be in the hospital with him watching him in excruciating pain. Many nights i would see the
stress on my parents face as their youngest son was going through horrific pain. Sometimes i would pray that God would take this disease away from my brother and give it to me so he wouldn't have to suffer anymore. #sicklecell patients already have it hard enough
with this disease now add on top of that racial bias that they have to deal with. Many times either me or my dad would have to advocate for him in the ER to get proper and urgent care and make sure his pain is adequately managed... The treatment my brother has received
Read 6 tweets
10 Mar 20
I truly feel for those who suffer with addiction and i am glad we have medications and tools to help with that as well.. It is truly devastating to lose someone to addiction and i hate hearing stories about it. I also have the same type of compassion for those
who suffer with chronic pain. My brother has #sicklecell and he suffers with chronic pain. Whenever he has his crisis he suffers excruciating pain that cuts deep to the core... We have a class of medications called opioids that have helped patients in pain for centuries..
It saddens me to see people demonize this class of medications which Have helped so many people cope with their pain. Yesterday I was taking care of this lady in our hospital who was going to be going to hospice the next day
Read 6 tweets
8 Mar 20
Thread on the opioid crisis****

I came across this article in the Journal of Pain Research by Dr. Jeffrey Singer et al. The title is called "Today's Nonmedical opioid users are not yesterday's patients: implications of data indicating stable rates of Nonmedical use and pain
Reliever use disorder". If you Havnt read this i would highly recommend it. When we discuss the opioid crisis we like to assign more blame to certain entities. The entity i hear alot in this discussion is pharmaceutical companies like Purdue Pharma and overprescribing that
Took place during the 90s when they marketed the drug Oxycontin. Alot of times we hear they were the cause of this crisis along with doctor overprescribing. Now this was Definately a contributing factor in getting this drug in the wrong hands resulting in NON-MEDICAL use
Read 7 tweets
1 Feb 20
Excerpt from article A Painful reality: Unequal access to Opioids in Developing Nations

"It is clear that the ripples of the American opioid epidemic are being felt around the globe. Because of this epidemic the word "opioid" has acquired a harshly negative subtext. Legislators
And philanthropists in the developing world are now opposing the import of opioids out of fear that increasing availability will trigger another epidemic of addiction abroad. Meg O'Brien founder of Treat the pain, a group devoted to bringing palliative care to developing
Countries believes this "opiophobia" is illogical. As she stated in a recent interview, "The U.S. also has an obesity epidemic, but no one is proposing we withhold food aid from South Sudan". The most recent World Health Organization List of Essential Medicines
Read 5 tweets
19 Jan 20
Pharmacy education post***

Why are the benzodiazepines Lorazapem, Oxazepam, and Temazepam recommended in the elderly?

Benzodiazepines are metabolized either through Phase 1 or Phase 2 metabolism
Phase 1 metabolism includes for example oxidation or reduction and turns the parent molecule into a more polar compound and eventual inactivation of the drug. Phase 1 metabolism involves the enzymes CYP2C19 and CYP3A4 and are responsible for benzos that undergo Phase 1..
Phase 2 metabolism involves conjugation of charged compounds and makes it more water soluble facilitating it into the bile or urine. So Phase 1 metabolism tends to decrease in the elderly and Phase 2 metabolism is for the most part preserved..
Read 5 tweets

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