Alina Chan Profile picture
Mar 22, 2021 12 tweets 2 min read Read on X
I kind of expected this day to come, but still surprised that it actually arrived.

I'm going to do a quick FAQ🧵 for the public (both scientists & non-scientists) who are just hearing about the possibility of COVID-19 / SARS-CoV-2 having emerged from lab or research activities.
Is it racist to ask whether COVID-19 emerged from a lab or from the wildlife trade in China? No.

Have racist people asked the question above? Yes.
More importantly, will people call you a racist if you ask whether COVID-19 emerged from a lab or from the wildlife trade in China?

Unfortunately, yes, it is quite likely they will call you a racist and more.

And yes, even if you're Asian, you could be called a race traitor.
If COVID-19 / SARS-CoV-2 actually emerged from research activities, does it mean that it is a bioweapon?

No.

Actually, the vast majority of pathogens that have leaked from labs worldwide are natural ones initially collected from natural hosts.

Not bioweapons. Very important.
Similar question: If COVID-19 / SARS-CoV-2 actually emerged from research activities, does it mean it was designed or created in the lab, like magic, NOT based on similar natural viruses that were collected & studied by labs?

No. Scientists don't have those awesome powers yet.
If COVID-19 actually emerged from research activities instead of a natural spillover, does that impact today's public health measures and vaccines?

No.
So today, someone tweeted at me, suggesting that if the virus actually came from a lab, then we must lock down now.

This is not true.

We're 1+ year into the pandemic now. Knowing if it came from a lab or wild animals shouldn't dictate public health strategy.
Knowing the origins of a virus is most important at the beginning of the outbreak so you can track it down - it's quite likely that the index cases may not have been in the city of detection.

If it came from a lab, that's useful to know because there could be data describing it.
Knowing the origins of COVID-19 is also important for future outbreaks.

If we know which origins scenarios are plausible, then we can act to mitigate the risk of COVID-19 happening again - anywhere in the world, in any lab or market, any time in the future.
This is the kind of dangerous FAQ:

Will finding out that COVID-19 emerged from research activities or wildlife trade in China lead to massive geopolitical consequences?

And also more racism?
I can't predict the answer. And this is why it is so scary for some experts and scientists to venture into this territory.

It would be the first time we're dealing with the possibility of a lab escape as the world together in real time (not decades later as an academic thesis).
But what I believe is, if we do not properly investigate the origins of COVID-19 and fail to implement measures to prevent such a pandemic from occurring again, then we are doomed to repeat this accident - whether by wildlife trade, environment destruction or research activities.

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More from @Ayjchan

May 2
Ralph Baric's interview with @covidselect reveals he was on the Feb 1, 2020 phone call with Farrar, Fauci, Collins and the Proximal Origin authors.

Did he reveal his plans from 2018 with the Wuhan Institute of Virology to put furin cleavage sites into SARS-like viruses?

oversight.house.gov/wp-content/upl…Image
@COVIDSelect Baric said he forgot about the Defuse proposal & did not mention it at the Feb 1 call.

I believe Baric sharing Defuse would've prevented the publication of Proximal Origin and the use of it to dismiss a lab #OriginOfCovid in US gov and to the public. Image
@COVIDSelect Baric also could've told them at the Feb 1 meeting that novel SARS-like viruses were being used in infection experiments at BSL2 at the Wuhan Institute of Virology aka the Wild West according to Jeremy Farrar.
Read 10 tweets
May 1
Peter Daszak, EcoHealth Alliance testified he didn't know Wuhan Institute of Virology bred 🦇, studied pangolin samples, engineered viruses without leaving a trace, and continued to collect viruses after 2015.

So how does he know they didn't cause Covid?
Daszak said he didn't know if WIV had started experiments described in the Defuse proposal and 🚨had not even asked them🚨.

He only had virus sequences from samples collected up to 2015. He believed that the WIV would've shared more sequences from 2016-2019 if they had them.
Reminder: EcoHealth Alliance still has not shared the sequences for the WIV's 220 SARS-CoV-1-like viruses (2022 interview) or 180 unique SARS-like viruses in their prior work not yet characterized for spillover potential (2018 proposal).
Read 5 tweets
Apr 22
Those dismissing a lab #OriginOfCovid have had to make numerous concessions over the past 4 years.

We now know Wuhan scientists conducted risky experiments with novel SARS-like viruses at low biosafety & planned in 2018 to create viruses with the traits of the Covid-19 virus.
We also know the data on early cases & Huanan market shared by Chinese scientists do not shed light on #OriginOfCovid

Proponents of natural origin continue to argue that it is the totality of evidence that supports their hypothesis but this could be said for lab origin as well.
The latest defense for a natural #OriginOfCovid is that, if a lab leak had occurred, the Wuhan scientists would have acted all suspicious and essentially given the game away, thereby putting themselves, their colleagues & their families in immediate and deadly peril.
Read 8 tweets
Apr 18
Freedom of speech is important in academia & science but difficult to navigate when it comes to politicized topics.

With #OriginOfCovid, some scientists, journals & reporters have competing interests & may be blamed if research they conducted, funded or glorified caused Covid.
On Tuesday’s hearing, chief editor of Science said the scientific community contributed to politicization of Covid & it was wrong to paint 'lab leak' as a conspiracy theory.

There was widespread consensus, Democrat or Republican, that #OriginOfCovid remains unresolved.
Several representatives asked for forward-facing solutions but none were presented. Today, the media continues to hang onto mistakes & politics of the past.

When confronted, many scientists or journalists who misled their peers & the public on #OriginOfCovid make no apologies.
Read 10 tweets
Apr 11
The @BulletinAtomic Pathogens Project successfully unified experts from opposing ends of #OriginOfCovid, representing diverse disciplines & cultures.

The outcome was a set of practical and high impact recommendations that policymakers are taking note of.
thebulletin.org/2024/04/how-to…
@BulletinAtomic Please see this thread for highlights from the report:
@BulletinAtomic The point of assembling an international task force of experts with truly different view points on #OriginOfCovid and what qualifies as risky research was so that the consensus recommendations would be robust to attacks from angry people on both sides of this issue.
Read 12 tweets
Apr 11
Leaders of scientific funding agencies said Proximal Origin was a nice job. According to the lead author of Proximal Origin, Farrar, Fauci & Collins had advised and led them as they wrote the letter.

So why won't @NatureMedicine put these leaders in the acknowledgements?
Image
The only scientist acknowledged in Proximal Origin arguably contributed much less than these 3 leaders.

He wasn't even at the Feb 1 meeting organized by Farrar where #OriginOfCovid was hotly debated and Proximal Origin was initiated.
Beyond what @Bryce_Nickels pointed out in his letter to @NatureMedicine & International Committee of Medical Journal Editors, the Proximal Origin authors failed to point out that their funder(s) had been involved in the work.
nature.com/nature-portfol…

Image
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Read 7 tweets

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