MEGA-THREAD OF ALL THE TIMES VIRUS LABS "LOST" DANGEROUS PATHOGENS
1/ SARS is documented to have escaped virus labs multiple times; twice from the same one
2/ The Institut Pasteur lost 2349 vials of SARS and once transported vials on a regular plane breaking protocols
(thread)
(I will post all sources at the end of the thread)
3/ More than 100 US labs with bioterror pathogens had faced federal sanctions for safety violations…
…and regulators allowed them to keep conducting experiments while failing inspections, sometimes for years.
4/ "U.S. laboratories reported more than 450 accidents during 2015 through 2019 while experimenting with some of the world’s most dangerous pathogens"
"In nearly all reported cases, regulators deemed the breaches serious enough to put workers at risk of becoming infected"
5/ Basically, we keep playing the Russian Roulette with viruses, unknowingly to most of the population.
6/ In 2007, leaked wastewater from a virus lab caused cattle to be infected with a disease from the 1967 epidemic .
7/ In 2001, anthrax stolen from a federal bioweapons lab killed five people and sickened 17 more. (ht @dwnhogendoorn)
8/ Some virus leaks get discovered very late, after they get the chance to infect dozens in multiple countries.
9/ Sometimes, incident investigations are not even able to pinpoint what went wrong, creating the risk that such events repeat indefinitely.
9/ These were only some of the known leaks.
Imagine how many more unknown one there are.
10/ I've personally worked on a consulting project for a major pharma company in behavioral mistakes leading to biological contamination (though not re: super-deadly pathogens) and I know how easily a mistake can lead to a leak.
11/ Why would any virus lab manager care, though? Leaks don't seem to materially affect careers
12/ So, even when there are known risks, little seems to be done to mitigate them
13/ If your jaw fell in disbelief, you're not the only one.
I'm also horrified by the risks posed by virus labs studying things that can obliterate us.
14/ Yes, virus labs routinely studying deadly pathogens do have some upsides, but their downsides are MASSIVE.
Moreover, is their upside any big?
COVID was sequenced in normal labs.
Also, it wasn't these high-risk labs that invented the vaccine.
What do we need them for, then?
15/ In any case, we should demand INDEPENDENT investigations. Not investigations performed by people whose salary depends on the investigation not revealing any danger, as it happened for the Wuhan lab dailycaller.com/2021/02/16/wuh…
Virus labs studying deadly pathogens are risky.
There are hundreds of leaks that the general public knows next to nothing about.
And recently, discussing the possibility of lab leaks seems to have become a taboo.
That's a dangerous path we're heading.
18/ Adding this important point.
Virus labs are only one of the possible sources of outbreaks.
To prevent future pandemics, we must both reduce its sources AND decrease connectivity / improve our response.
19/ I wonder the extent to which this process puts us at risks – not necessarily "arms race" as in for weapons, but even just competition between labs or even researchers for funding and/or career opportunities
“Create a UserPromptSubmit hook (global settings). Script echoes: If 8+ tool calls, append one optimization hint (reusable skill, memory pattern, or workflow fix). One sentence. Skip if exploratory.”"
2) Skills audit
"Create a skill that lists all my installed skills (project & global level) with their line counts. Then ask the user which to review for improvement opportunities (conciseness, clarity, overlapping scopes, token efficiency).”
3) Claude audit
“Create a skill that reads all CLAUDE .md files and checks for: redundant instructions, verbose phrasing, and content that could move to memory. Present findings and ask if the user wants to implement them.”
Highlights from today’s Jeff Bezos’ talk in Turin 🇮🇹:
“Advice to young people: go work to a company where you can learn best practices”
I fully agree: it should also apply to politicians, educators, and other high-leverage roles.
1/N
“You can be an entrepreneur within a company; good companies don’t eject mavericks but empower them.”
I add: it’s so important to select a great first job and first boss; it’s sad it’s mostly left to chance, esp. comparing how much time is spent studying and how little interviewing.
2/N
We interviewed @linaashar, founder of Dreamtime Learning, who has very interesting thoughts about education.
Some of my favorite quotes:
“I keep teaching kids about their brains and their behavior in every session. Because if kids can master their brains, their thoughts, their actions, and therefore their behaviors, they're going to be successful. That's a given. But if they master only what is calculus, or what this is and what that is, even though they may get an A+, success is not a given. Because you can master content, but if you have to master yourself, you're lost.”
(link at the bottom; 1/7)
“We do not [as society] design the education system or the learning sessions in the way their brain actually works.”
2/7
“If their whole school time is spent on learning the core curriculum, where is the time for kids to specialize? Where do they get those 10,000 hours that they need to become a specialist? So you have to free up time in the child's day for them to become highly specialized.”
3/7
I recently got a small grant (courtesy of Kanro, Vitalik Buterin's foundation) to produce some educational materials regarding the pandemic response.
These 10 one-pagers are the first batch of educational materials.
Any feedback?
1/10
Some more background about the one-pagers. They are meant for people who are already onboard with the need to properly react to an eventual future pandemic but don't have the vocabulary or examples to explain to others what they can do and why.
2/10
A simple model to understand indoor infection risk