3/24
Honeycomb-like structure, a rare cause of myocardial ischaemia has multiple communicating channels divided by thin septa. Angiographically fuzzy & hazy appearance often without significant stenosis, they're best detected on high-resolution IVUS/OCT academic.oup.com/ehjcr/article/…
4/24
In this case, lotus root-like appearance on #OCT was caused by spontaneous recanalisation of occlusive thrombi, uniquely at the site of coronary spasm. Spontaneous recanalisation subsequently formed multi-channel lumens in this patient with NSTE-ACS. academic.oup.com/ehjcr/article/…
5/24
Intravascular imaging in #SCAD aids diagnosis, balloon sizing, & assessment of response to treatment. This SCAD, where #OCT showed an intramural haematoma, was impressively treated by a large cutting balloon, with resolution as seen on OCT academic.oup.com/ehjcr/article/…
6/24
This #EAPCI expert consensus is an excellent resource. Part 1 focuses on the use of intracoronary imaging for coronary interventions in:
-Diagnostic assessment of coronary lesions
-PCI guidance & optimisation
-Identifying mechanisms of stent failure
7/24
Intravascular imaging is invaluable in identifying mechanisms of stent failure: thrombus/stent malapposition/edge dissection.
Here are OCT images of a case of massive acute stent thrombosis, subsequently fixed with balloon dilatation academic.oup.com/ehjcr/article/…
8/24
This type 3 Kounis Syndrome presented with very late ST & coronary evaginations, seen on #OCT
Follow-up intracoronary imaging may be important to confirm potential coronary evaginations in such cases, especially in sirolimus eluting stents doi.org/10.1093/ehjcr/…
9/24
Very late BMS stent thrombosis:#OCT showed high-intensity area protruding inward stent, attenuated, w relatively signal-poor region,possibly indicating mixed thrombus.
On #IVUS, an echolucent structure inside the stent was seen, consistent w thrombus doi.org/10.1093/ehjcr/…
10/24
Troubleshooting w #IVUS: In severe strut malapposition due to partial crush after post-dilatation, IVUS probe placed in ‘live view’ between vessel wall & crushed stent, visualised initial section of crushed struts, enabling wiring of stent true lumen academic.oup.com/ehjcr/article/…
11/24
Given differences in resolution, tissue characterisation & need for contrast, IVUS & OCT have pros & cons
-#IVUS:preferred in CTO,ostial LM&CKD
-#OCT:better at detecting thrombus,culprit plaque in ACS; residual edge dissection, incorrect wire positions & stent malapposition
12/24 #IVUS is an invaluable tool in #zerocontrast PCI. In this case of contrast allergy, #IVUS w ChromaFlo mode was used in PCI to CTO LAD. IVUS helped identify the entry point of proximal cap, lesion assessment pre- stenting & optimisation post-stenting doi.org/10.1093/ehjcr/…
13/24
In this case report of gadolinium-based contrast use, @AnkurGuptaMD et al. performed successful two-staged CTO PCI to both LAD & LCx with #IVUS guidance in a patient with severe anaphylaxis to iodinated contrast academic.oup.com/ehjcr/article/…
14/24
In this case, #OCT was crucial in guiding the percutaneous Rx of a giant true saccular coronary aneurysm in proximal LAD, which was treated with a polytetrafluoroethylene covered stent academic.oup.com/ehjcr/article/…
15/24
Intravascular imaging is a crucial part of every calcified vessel Rx algorithm, as it dictates lesion modification strategy. See this #IVUS image w calcium fractures created by intravascular lithotripsy treatment in a heavily calcified vessel doi.org/10.1093/ehjcr/…
16/24
Intravascular imaging helps clarify diagnostic/ angiographic uncertainty in the setting of ACS.
IVUS/OCT can delineate luminal discontinuity/plaque disruption & thrombus.
OCT is capable of distinguishing red and white thrombus as well academic.oup.com/eurheartj/arti…
17/24
In this 68 yo STEMI pt w thrombus in distal left main bifurcation extending to ostial LCx & LAD, excimer laser coronary angioplasty ELCA was used to ⬇️ intracoronary thrombus with OCT guidance. Check out the impressive pre & post- ELCA #OCT images doi.org/10.1093/ehjcr/…
18/24
In this ITP patient, presenting with ACS, red thrombus visualized on #OCT in the RCA, helped decision-making in terms of revascularisation. He was treated with plain old balloon angioplasty, with satisfactory outcome as seen on OCT re-analysis academic.oup.com/ehjcr/article/…
19/24
Intravascular imaging to define plaque morphology in ACS: in this case at least two distinct plaque morphologies of OCT-defined plaque erosions were further defined by near-infrared spectroscopy (#NIRS) & coronary angioscopy academic.oup.com/ehjcr/article/…
20/24
Is the presence of cholesterol crystals on OCT a precursor of ACS? See the extraordinary progression of this non-obstructive lipid-rich plaque with cholesterol crystals and thick fibrous cap, 12 months later, on #OCT academic.oup.com/ehjcr/article/…
21/24
Intravascular imaging is 🔑in defining plaque morphology.
Here, the regression of vulnerable non-culprit lipid-rich plaque was observed using serial near-infrared spectroscopy–IVUS & OCT measurements after aggressive cholesterol-lowering treatment academic.oup.com/ehjcr/article/…
22/24
This two-part case series demonstrates the role of #IVUS in identifying localisation & degree of inflammation of coronary arteritis: ambiguous typical three-layer structure of arterial wall and extended low-echoic areas within adventitia academic.oup.com/ehjcr/article/…
1/25
How would you tackle this heavily calcified LAD with calcified #nodule that was appropriately identified by intravascular imaging? #OCT doi.org/10.1093/ehjcr/…
2/25
Calcified lesions are top of the totem pole of complex PCI
Main armamentaria are balloon-based #IVL & ablation-based (rotational/orbital) techniques, while ancillary tools eg guide extension catheters are useful too. eurointervention.pcronline.com/article/intrav…
2/24
🎯 The rationale of #LAAO
🔸 In non-valvular #AF patients, 90% of thrombus is located in the #LAA
🔸 These thrombi embolise to the 🧠 & cause #stroke
🎯 Don't miss the ‘#EHRA_ESC#EAPCI expert consensus document on catheter-based #LAAO –an update’ doi.org/10.1093/europa…
3/24 #LAA closure devices should be safe, efficent and easy to deploy.
📌 Currently available catheter-based devices for #LAAO have different principles.
2. It’s cardiac amyloidosis! Here is a great resource from @escardio WG on Myocardial and Pericardial Diseases to start with doi.org/10.1093/eurhea…
3. First, what is amyloidosis?
Amyloidosis occurs when abnormal proteins misfold and deposit in tissues as beta-pleated sheets. These disrupt tissue structure and can cause damage to many different organs.