1) THE AGEING SPONTANEOUSLY HYPERTENSIVE RAT (SHR), COVID-19 HEART DAMAGE AND BETA-MYOSIN HEAVY CHAIN PROTEIN - MISSENSE MUTATIONS (AMINO ACID SUBSTITUTIONS)

Looking at the ageing SHR we notice that it suffers depressed myocardial contractile function and ventricular fibrosis.
2) Both of these occur post COVID. This is due to remodelling of the extracellular matrix and may result in part from age-related alterations in beta-adrenergic receptor dynamics and a shift from alpha- to beta-myosin heavy chain (MHC) protein.

This change is due to an amino
3) acid substitution, a "missense mutation." LMNA missense mutation, for example, manifests with overlapping mandibuloacral dysplasia and progeria syndrome.

Fast parallel proteolysis (FASTpp) should be done for Long COVID patients.

It is most likely SARS-CoV-2 is taking
4) the Rembrandt that is our individually unique genome and, like so many gleefully evil gremlins, moving the paint molecules around one by one, leaving behind a dysfunctioning Jackson Pollack.

en.wikipedia.org/wiki/Missense_…

pubmed.ncbi.nlm.nih.gov/8682057/

sciencedirect.com/science/articl…
6) It's like a villain out of Batman. One that would gleefully take RNA and juggle the amino acids around. It leaves a contorted, twisted nonfunctioning protein behind then moves on to the next. How does it do this without damaging the virus itself??

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More from @Parsifaler

6 Apr
1) AEROSOLS AND BIOWEAPONS: GENETIC TROJAN HORSES

A must read paper from Jan. 1, 2010, titled Advances in Targeted Delivery and the Future of Bioweapons discusses arming viruses with a destructive or even deadly payload to be delivered to an unsuspecting population.
2) In general, these viruses act as vehicles that carry and deliver foreign genes to the body. The theory is that infecting an organism with one of these novel viruses will lead to the expression of the foreign gene in the affected tissues' cells. In turn, the expression of the
3) gene would initiate the synthesis of the active substance (the gene product), which would then exert its effect on the body. In effect, the virus, similar to a Trojan horse, is used to smuggle a foreign substance into the body and deliver it to a particular tissue where it
Read 6 tweets
5 Apr
1) ACE2 SHEDDING AND THE COVID-19 SPIKE PROTEIN

Higher levels of plasma ACE2 are associated with greater risk of death, cardiovascular and non-cardiovascular deaths, stroke, myocardial infarction, diabetes, and heart failure independent of age, sex, ancestry, and traditional
2) cardiac risk factors. The spike protein the original SARS virus was demonstrated to have the ability to cause shedding of ACE2 from the cell membrane, increasing plasma ACE2.

Blood ACE2 concentration, in comparison to established risk factors, was the highest ranked
3) predictor of death, cardiovascular and non-cardiovascular deaths, and superseded many other common risk factors in explaining variation in stroke, myocardial infarction, and heart failure. We observed that male sex, higher blood pressure, smoking, higher BMI, and older age
Read 5 tweets
5 Apr
1) TYING IT ALL TOGETHER WITH TOXICOLOGY: TOXIFICATION OF THE BODY

ACE2 is ubiquitous. Attacked a7nAchR receptors induce neuroinflammation. Let that sink in.

The strongest, and most damaging, responses of the immune system are in relation to toxic exposure. "Chemical AIDS"
2) was once a term (incorrectly) used to describe chemical-induced immune dysfunction. A major theory (which I believe to be correct) circulating now is that COVID-19 is due to the body attacking its own ACE2 receptors. They are EVERYWHERE.

You would be hard pressed to find
3) a more universal receptor to target. Carrying out an assault on ACE2 receptors is like carrying out a Dresden Bombing of the body. One that targets all of the "tactical strongholds."

Several sources suggest that epigenetic modifications following exposure to drugs and
Read 7 tweets
5 Apr
1) STRONGER THAN EVER? BEWARE

I have heard from many friends that have had COVID and from those that have had the vaks that they are "stronger than ever." I believe, contrary to their jubalistic tropes, that this is a sign of accelerated aging already taking place. I refer
2) everyone to the story of Liam Hoekstra, a child with Myostatin-related Muscle Hypertrophy. Experts have said the condition is so rare in humans, scientists don't know how many people have it.

For Liam, the result was having 40 percent more muscle mass than other children his
3) age. He is terrifically strong, quick as a rabbit, has the metabolism of a gerbil and almost no body fat.

Levels of myostatin have not been studied in COVID-19 or in those receiving mRNA therapies. It is imperative that these levels be studied.

mlive.com/news/muskegon/…
Read 4 tweets
4 Apr
1) IMMENSE PROTEASE DYSREGULATION. COVID-19 CAUSES THE BODY TO CATABOLIZE ITSELF. IVERMECTIN, DEXMETHASONE, HCL AND VIRTUALLY EVERY EFFECTIVE COVID-19 DRUG IS A PROTEASE INHIBITOR. VITAMIN D DEFICIENCY IS PRESENT BECAUSE THE BODY IS TRYING TO STOP PROTEOLYTIC ACTIVITY.

If one
2) analyzes all of the evidence to date as to what COVID-19 does, what treatments have effect and what processes are involved in the pathogenesis of the disease it becomes clear that the disease is one of immense protease dysregulation. From Serine proteases to Cysteine proteases
3) to Threonine proteases it is clear that the body is hypercatabolizing itself, burning itself out at all ends. From telomere shortening to senescence to cancer and cognitive decline. All can be traced to this "virus" that has been created to reprogram our cells to consume
Read 5 tweets
4 Apr
1) SPIKE PROTEIN SEQUENCE SIMILARITY TO HEPCIDIN MAY EXPLAIN THROMBOTIC EVENTS. HIGH LEVELS OF HEPCIDIN PROGRESS SOME CANCERS AND CAN CAUSE THROMBOSIS

The spike protein of SARS-CoV-2 has been shown to have sequences which bear similarity to hepcidin. It is possible that the
2) body may suddenly be "tricked" by the spike protein into believing it has far too much iron, and begins to degrade it. This perceived lack of iron (which becomes an actual lack of iron) can cause reactive thrombocytosis.

An additional point of interest is that certain
3) cancers thrive on an excess of hepcidin due to its ability to influence iron homeostasis.

Inflammation is also regulated by Hepcidin, as IL-6, STAT-3 and Hepcidin are intrinsically linked in inflmmatory states.

Investigation into Hepcidin levels post mRNA therapy should
Read 4 tweets

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