Dr. Tom Frieden Profile picture
Apr 30, 2021 21 tweets 6 min read Read on X
Globally, the end of the pandemic isn't near.

More than a million lives depend on improving our response quickly.

Don’t be blinded by the light at the end of the tunnel. There isn't enough vaccine and the virus is gathering strength & speed. Global cooperation is crucial. 1/
India’s surge is a reminder that the virus is learning about and adapting to us faster than we're learning and adapting to it. Covid, fueled by variants, is an ongoing & increasing risk. The pandemic is more severe than ever—more transmissible, more deadly, more human fatigue. 2/ Image
Dazzling scientific progress resulted in Covid vaccines that are more effective than many experts dared to hope. But although Israel, the UK, and, soon, the US will have a new reality with the virus largely tamed by vaccines, global vaccination lags badly. 3/ Image
Even in the best of circumstances, vaccines take months to control the virus. And we’re in far from the best of circumstances. Globally, vaccines would not crush the curve in the short-term even if there were enough of them—which there aren’t. 4/ Image
It takes weeks to months to roll out vaccines and weeks for protection to kick in. Vaccines don’t help people already infected with Covid and probably don’t help much after exposure. To stop spread now, we need to mask, distance, reduce travel, and prevent superspreading. 5/
Our current vaccine infrastructure can’t be relied on to meet the needs of the world. Countries with excess supply can make a dent, but vaccine production needs a step-function increase. Until much more vaccine is available, masks, distancing, less travel are all essential. 6/
All types of vaccines that are proven to be effective need to be scaled up as rapidly as possible. Novavax, J&J, AstraZeneca and others are all important, but mRNA vaccines are the most promising. They are our insurance policy against variants, boosters, and production delays. 7/
mRNA vaccines are also quicker to scale up, and they’re likely safer and more effective. Handling is getting easier, and cold chain problems can be addressed. They’re our best hope for an end to the global pandemic. But current capacity is nowhere near the global need. 8/
Yes, rosy estimates show there'll be enough vaccines in 2021, but companies missed 2020 production projections by 96% & overall production is at only 1/4 of projection for 2021. Variants, boosters, safety signals, production delays all very real risks. bit.ly/3nzQvIg 9/ Image
We can’t bet lives and global recovery on uncertain vaccines and production. Regional mRNA manufacturing hubs are crucial to provide the best vaccines globally ASAP. Doing so will take longer than we wish, which is why we must start right now. politi.co/3e1DqEj 10/
India, South Korea, Singapore, Brazil and other countries in Latin America, South Africa, Senegal, Rwanda all have potential to establish vaccine manufacturing capacity and could become providers of vaccines globally. CureVax might be another resource. 11/
Transferring mRNA technology is essential. The technology is outlined in this fascinating @nytimes piece. The pandemic is the world’s most important problem. We should act accordingly. nyti.ms/3eBiOly 12/
Transferring technology and stepping up production globally is the most important step the Biden administration can take to help end the pandemic. US taxpayers funded the Moderna vaccine. Not sharing this technology puts us at risk if even more dangerous variants emerge. 13/
Variants, wow! Check out the stunning march of B117 across the US. Even with more than half of our adult population fully vaccinated, we still face risk of outbreaks, and unvaccinated people are facing more danger than ever. 14/ Image
In the 1918 pandemic, in many places, the second wave was deadlier than the first. I’m concerned we’re at the most dangerous phase of the pandemic yet. Covid is deadlier, more transmissible, in more places, circulating at higher levels, and there’s more human fatigue. 15/
Globally, there were 1.8 million deaths reported from Covid in 2020. At the current rate, there will be even more deaths in 2021. But this isn’t inevitable; pandemics aren’t natural disasters. We can control Covid. Effective action can save at least a million lives this year. 16/
Variants remain the biggest wild card, but we’ve learned a lot about the virus and how to limit its impact. Protection measures work. 17/
Six steps we must take now to deal with explosive spread globally.
1. Protect health care & healthcare workers
2. Mask up
3. Distance and avoid superspreading
4. Continue essential services, including schooling
5. Vaccinate, especially HCW and older people
6. Learn and adapt
18/
For each of these six, we need a focused, well-managed, accountable approach. We MUST do better protecting health care and health care workers. Doing so will save lives from Covid and from diseases that become deadlier when care is disrupted. bit.ly/3e7Z0ay 19/ Image
It’s possible to beat infectious diseases. These stories of success give me hope. If we work together across borders to fight Covid and invest in preparedness, we can save millions of lives. preventepidemics.org/ETDH 20/
Covid has shown us the costs of failure, but a safer and healthier future is possible. 21/end

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More from @DrTomFrieden

May 3, 2023
Updated Covid booster recommendations and the unwinding of the public health emergency in the United States have raised questions and highlighted lingering challenges. How should we be thinking about these developments? Who should get a booster this spring? 1/thread
Covid hasn’t gone away, but it no longer poses the same threat to most people it did in the first years after its emergence. This is due, in large part, to lifesaving vaccinations and treatment, and also to prior infections, which reduce the risk too. 2/
Our wall of immunity, built up from both vaccinations and infection, is strong—but it’s not impervious. Protection wanes, and the virus continues to mutate. Even now, older adults and medically vulnerable people remain susceptible to severe illness and death. 3/
Read 19 tweets
Apr 8, 2023
In New York City, Covid killed more people than any other cause in the pandemic’s first year and caused life expectancy to drop by 4.6 years on average, according to the newly released annual report of NYC vital statistics. Confirmation of a devastating toll. 1/thread
What gets measured can be managed, which is why reports like this are crucial. More than 200 New Yorkers die every day, including >50 people under age 65, a data point I tracked closely as NYC Health Commissioner and focused intently on bringing down. bit.ly/41cFZcm 2/ Image
Every life counts. A moving piece published last week in @nytimes shows vividly the necessity—and challenge—of tracking all births and deaths. 3/ bit.ly/3Gmll1O
Read 10 tweets
Mar 17, 2023
The past three years of fighting Covid feel like a fog of war. Although everyone wants to move on, we must reckon with how bad the pandemic was—and how much worse it could have been. 1/thread
20 million excess deaths have occurred during the Covid pandemic—more than all but the two other leading causes of death, cardiovascular disease and cancer. Without vaccination, measures to reduce infections and lifesaving medical care so many more lives would have been lost. 2/
Those who are intent on undermining public health action argue that there was nothing we could have done to counter Covid, that all of the infections and deaths were inevitable. But they ignore that some places had much lower rates of infections, hospitalizations and deaths. 3/
Read 15 tweets
Feb 23, 2023
Masks have been an effective tool throughout the Covid pandemic, despite erroneous claims to the contrary. 1/thread
The widely cited Cochrane review on masks was poorly done and even more poorly communicated. Regrettably, researchers analyzed the wrong datasets, in the wrong way, and overstated their conclusions—leading to sweeping and inaccurate characterizations. 2/
Many nuances around mask type, setting, behavior, and policy are explained in this helpful piece by @dr_kkjetelina. bit.ly/3ErwuNN 3/
Read 15 tweets
Feb 4, 2023
Over the past decade, global smoking rates dropped by 23% and 750 billion fewer cigarettes are sold annually. But despite this progress, tobacco is still the world’s leading cause of death and unless we do more, will kill ONE BILLION people in this century. 1/thread
The FDA recently announced a national ban on menthol cigarettes and a new California law to curb flavored tobacco was overwhelmingly affirmed by voters in November. Big Tobacco's reaction to these two recent public health wins underscores the fight we have ahead of us. 2/
Why are these wins significant? Big Tobacco has a long history of targeting Black communities with menthol cigarettes. The FDA ban could undo shocking disparities in lung cancer deaths suffered by Black Americans compared to their white counterparts. bit.ly/3JtXQWQ 3/
Read 8 tweets
Jan 29, 2023
Amid discussion of the future of Covid vaccination, we can’t lose sight of the present: Only 1% of immunocompromised people in the US received a full set of Covid vaccinations as of Aug. That’s a colossal failure. The 5 steps to avoid failure in public health explained 1/thread
500 people are still dying from Covid every day. That’s not normal and it doesn’t have to happen! Immunocompromised people—along with the elderly—are at the highest risk of dying from Covid. 2/
Vaccines are remarkably effective against severe disease, but their protection must be reinforced, especially for vulnerable people. Boosters reinforce our protection, and a new CDC study underscores their importance. bit.ly/4062XCq 3/
Read 24 tweets

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