Evidence strongly shows the very opposite of this widespread myth.
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Yet despite the constant drumbeat of science showing the healthfulness of “industrial seed oils”, an equally persistent drumbeat from the likes of Mark Hyman and others maligns them.
What is the truth?
Well, one paper published in the European Journal of Clinical Nutrition in fact showed that olive oil, soy oil, and cod liver oil all decreased some markers of inflammation. pubmed.ncbi.nlm.nih.gov/21326271/
And a recent article reviewing all currently available evidence concluded human trials consistently show that omega-6 fatty acids, a constituent in “seed oils” blamed for their supposed ill effects, do not cause inflammation. pubmed.ncbi.nlm.nih.gov/29610056/
And some of the highest quality observational evidence shows a dose-response relationship between degree of unsaturation of fatty acids consumed and reduction in heart disease risk. onlinelibrary.wiley.com/doi/10.1111/j.…
Where do these myths about vegetable oils come from? Well, a few places: 1. The naturalistic fallacy- vegetable oils are “unnatural” and therefore they cannot be healthy, right? But this is a fallacy. Cooking is unnatural. Shoes are unnatural. Toothbrushes are unnatural.
2. Mechanisms governing inflammation- omega-6 fatty acids might to “feed” inflammatory biochemical pathways. However, the clinical trial evidence does not bear these mechanisms out.
3. Other mechanisms such as endothelial dysfunction and oxidation. However, again, these mechanisms are contradicted by the available clinical trial evidence.
What the case of seed oils teaches us is that coming to conclusions based on mechanisms is inappropriate: we need to pay attention to the human evidence.
Now, vegetable oils may increase the calorie density of foods and make it easier to overconsume calories. However, compared to the alternative, such as butter, vegetable oils are much healthier. ncbi.nlm.nih.gov/pmc/articles/P…
Our recommendation: use oils to the degree that you can keep overall calorie intake low, but definitely use them in place of traditional cooking fats like butter or lard. The science supporting this recommendation to prevent disease is among the strongest we have in nutrition.
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"It is incontrovertible that skipping meals while maintaining adequate nutrition is not only good for you but will make you live longer"
But what do the data say?
First, some context.
On the @joerogan podcast and others, Sinclair claims that he only eats a single meal after 6pm, and explains that this is optimal because humans are made more resilient by doing such a thing.
In 2016, his license was placed on probation for "unprofessional, dishonorable or unethical conduct" for prescribing opioids, benzodiazepines, and other medications despite normal physical exams--and prescribing controlled substances to family members.
Is inflammation the cause of heart disease, and not cholesterol?
A thread👇
There is better evidence for cholesterol (specifically LDL) as being causative in cardiovascular disease than almost any other theory in modern medicine.
So many lines of evidence converge on the same conclusion that if this theory is wrong, then almost all of modern medicine is also false. A figure from a consensus paper from the European Atherosclerosis Society makes this clear. academic.oup.com/eurheartj/arti…