Professor Philip Nolan Profile picture
Jul 19, 2021 9 tweets 4 min read Read on X
The data are saying one thing: be very cautious faced with the delta variant. We are seeing a very steep rise in cases, comparable to or steeper than the early part of previous waves. 1/9
This will not translate into severe disease and mortality in the same way as before, but numbers in hospital are rising: 101 this morning. The ratio of admissions to cases is 16 admissions per 1000 cases, overall we are tracking 15-25 admissions per 1000 cases. 2/9
Weekend effects typically give low case counts on Sunday and early in the week; case counts over the next few days will be an important indicator. 3/9
Growth rate is currently 5-7% per day, which would give a doubling time of 10-15 days; these estimates are quite unstable given the very rapid increase in cases in the last few days 4/9
While cases are concentrated in older teenagers and younger adults, we are beginning to see an increase in incidence across other age groups, including those aged 65 and older. 5/9
Incidence in those aged 16-29 years is rising rapidly, is higher than we have seen since end of January 2021, and higher than the October 2020 peak. 6/9
Incidence varies by county, but most counties have a 7-day incidence significantly greater than 50% of their 14-day incidence, indicating rapid growth in those counties. 7/9
We need to limit transmission: a wave of infections in young people will cause severe illness and long-term complications in a sizeable minority, and will break through the protection of vaccination to cause dangerous infections in older and vulnerable people. 8/9
We know what we need to do: support those not yet fully vaccinated to socialise safely outdoors and distanced, and we all need to self-isolate and seek a test if symptomatic, avoid crowds and crowded spaces, and take the basic public health and hygiene precautions. 9/9

• • •

Missing some Tweet in this thread? You can try to force a refresh
 

Keep Current with Professor Philip Nolan

Professor Philip Nolan Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @PhilipNolan_MU

Dec 18, 2021
Omicron will be a very significant challenge, but we are acting early, quickly and comprehensively. If we take a booster vaccine when offered, significantly limit contacts, mitigate risk, self-isolate if symptomatic and restrict movements if a contact, we can get through it. 1/22
The purpose of the formal restrictions is to significantly reduce risky social contact, the opportunity for the virus to transmit; they are to reinforce a call to all of us to prioritise our socializing over the coming weeks to a small group of people who matter most to us. 2/22
We already have, by reducing our contacts and adherence to basic public health measures, begun to bring infections and hospitalisations down after a significant surge of the delta variant in early November. This was difficult, but we did it together. 3/22
Read 22 tweets
Nov 21, 2021
Let’s think and act positively. We can, with collective action, control transmission of SARS-CoV-2 again, and relieve the pressure of COVID-19 on our healthcare system. The effective reproduction number is currently estimated at around 1.2 1/12
If we can reduce our close social contacts by 30%, and/or mitigate the risks of those social contacts by 30%, we will have done enough to see the level of infection, case numbers and ultimately hospitalisations decline. 2/12
The more we prioritize and limit our social contacts, and mitigate those risks, the faster things will improve. The rising numbers of people in hospital and ICU are an urgent call to action. 3/12
Read 12 tweets
Nov 17, 2021
The latest modelling of SARS-CoV-2 infection in Ireland shows that we urgently need to reduce transmission if we are to avoid further dangerous increases in cases and hospitalisations. Stay home with symptoms, limit contacts, use basic mitigations. 1/20
The current surge in disease began soon after the relaxation of measures on 20 Sept 2021, and accelerated from 22 Oct 2021 through the mid-term break. The increase in effective social contact is the primary driver, along with waning vaccine immunity. 2/20
Vaccines are very effective, but over time the immune defence against simple infection wanes. Fortunately, protection from severe disease is well maintained. The waning immunity means that increasing social contact causes a large and increasing force of infection. 3/20
Read 20 tweets
Oct 16, 2021
Why are SARS-Cov-2 infections increasing in Ireland? It’s complex, but most likely a mix of increased mobility and social contact since late September, slippage on transmission prevention measures, and more social mixing indoors. 1/16
We had high but stable levels of infection through September 2021, but this was created by a very dynamic and delicate balance between increasing vaccine protection suppressing the virus, and increasing social contact creating opportunities for the virus to spread. 2/16
We started at a disadvantage compared to most of Western Europe. We were hit by a very large wave of delta infections in July, with most of the population under 50 not yet vaccinated, driving daily cases from 300 to 1800 per day between June and August. 3/16
Read 16 tweets
Sep 22, 2021
There is no evidence that the reopening of schools has led to an increase in transmission or levels of infection amongst school-going children or more widely across the population. 1/14
The level of infection in children and adolescents had increased in the course of the summer as the delta variant increased the rate of transmission. 2/14
This had stabilized at a high level in children aged 12 and under, and decreased markedly in 13-18 year olds, as vaccination reduced incidence in adults and adolescents, and began to reduce the probability of children becoming infected. 3/14
Read 14 tweets
Sep 12, 2021
A lot of commentary saying that most or all schoolchildren will be infected with SARS-CoV-2 in the coming months, based on an uncritical reading of this modelling study. It is highly unlikely that the scenario modelled will happen in the real world. 1/12

medrxiv.org/content/10.110…
First, it’s not plausible. In the 12 weeks after primary schools reopened in March 2021 we detected 5,279 cases in children aged 5-12 years, or just under 1% of the population. The vast majority of these infections were transmitted in the community, not in school. 2/12
Even if delta is 50% more transmissible than alpha, it’s a long way from 1% of the population to 50-75% of the population becoming infected in 12 weeks; note also that most transmission was in the community, and the majority of the community is now vaccinated. 3/12
Read 12 tweets

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

:(