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David Windt Profile picture
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19 Aug, 142 tweets, 121 min read
"A British public health study has found that protection from either of the two most commonly used COVID-19 vaccines against the now prevalent Delta variant of the coronavirus weakens within three months."

reuters.com/business/healt… Image
"Breakthrough infections are occurring more frequently than previously reported"

"While...breakthrough infections are increasing, the studies showed hospitalizations remained stable, an indication the vaccines continue to hold up against severe illness."

news.yahoo.com/miserable-brea… Image
"Let's be real, here: Breakthrough infections are sort of okay," Larry Corey, a virologist at Seattle's Fred Hutchinson Cancer Research Center, tells the Journal."
news.yahoo.com/u-covid-19-bre…

Is organ damage, #LongCovid, and death "sort of okay" too?

#MovingTheGoalPosts Image
#Wisconsin: "breakthrough infections one third of cases statewide last month"

"The La Crosse County Health Department has reported a 163% increase in local COVID-19 cases over the past month, with percent positivity rising from 1% to 6.5%."

lacrossetribune.com/news/local/loc… Image
"Here we observed the co-occurrence of immune escape mutations and vaccine breakthrough infections despite the presence of COVID-specific immune response in hosts."

medrxiv.org/content/10.110… Image
"If the Wisconsin study finding holds up, then people with breakthrough infections—many of whom do not develop COVID symptoms—can unknowingly spread the virus. “It [is] an alarming finding,” explains Katarina Grande ... who led the study."

nationalgeographic.com/science/articl… Image
Unvaccinated children "can be infected. They can have severe illness and they can transmit the virus."
npr.org/sections/healt…

So just like adults.

And presumably, just like adults, vaccinated children also can be infected, can have severe illness and can transmit the virus. Image
Another vaxxed parent has infected their unvaxxed child. Yet the mother of the hospitalized 3-year-old blames the unvaccinated:

"maybe if more people will be vaccinated, I wouldn’t have had the exposure that caused me to bring this illness to my daughter"
wfla.com/community/heal… Image
"Across Los Angeles County, cities and neighborhoods including West Hollywood, Venice and Santa Monica now report some of the most infections, even though their vaccination rates are higher than in poorer areas such as East Los Angeles"

wsj.com/articles/in-lo… Image
Or — and I know this sounds crazy, but hear me out — maybe it was all the adverse events, the failure to block transmission, and the waning efficacy that 'tanked confidence' in the AstraZeneca vaccine?



ImageImageImage
Worse Than Expected™ — Vaccine Efficacy Edition

"Vaccinated people appear to be getting the coronavirus at a surprisingly high rate ...now, there’s growing concern that vaccinated people may be more vulnerable to serious illness than previously thought."
bloomberg.com/news/articles/… Image
"Over half of the population was fully vaccinated by March 25 ...it looked like the country was on its way to herd immunity ... [Today] Half of the seriously ill COVID patients currently hospitalized in #Israel were fully vaccinated"

businessinsider.com/israels-covid-…

"looked like" ImageImageImage
"the first 10 cases of the AY3 coronavirus strain [a highly infectious variant] ... found in #Israel", a country that already provides a fertile breeding ground for more infectious variants.
israelnationalnews.com/News/News.aspx…

Expect further evolution towards full vaccine resistance. Image
"vaccine-resistant variants are highly likely to cause more (severe) disease in vaccinated as compared to non-vaccinated subjects"

"... a tremendous risk to all health care workers as the vast majority of them have already been vaccinated"
geertvandenbossche.org/post/unravelli… Image
"The level of breakthrough cases is much higher than anticipated"

Houston, Texas: Rice University, 98.5% vaccinated, shifts to online classes, for "time to assess the results of its recent testing"

nytimes.com/2021/08/20/us/…

My assessment: the vaccines won't bring herd immunity. Image
"Bay Area teen tests positive for breakthrough COVID-19 during college move-in"

"According to the fully vaccinated 18-year-old, Huang began experiencing a tell-tale symptom of COVID-19, a loss of smell, right after moving into his dorm at USC."

abc7news.com/breakthrough-c… Image
#Ireland: "St Vincent’s hospital in Dublin is admitting a “worrying” number of double-vaccinated patients for treatment for Covid-19"

"we’re seeing a significant number of breakthrough cases"

independent.ie/world-news/cor…
Image
"that kids are transmitting the coronavirus to family members is unnerving many parents all over the U.S., and putting extra stress on many households as children head back to school"

npr.org/sections/healt…
Image
#Florida: "Orange County leaders announced Monday that pediatric cases in children ages 5 to 14 make up roughly 20% of all new COVID-19 cases in the county, making them the age group contributing the most new infections in the area."

clickorlando.com/news/local/202… Image
"A 16-year-old football player at Westwood High School died from COVID-19 and pneumonia ... Buckner said her son, who had asthma, was vaccinated. She said Zo appeared to be the picture of health at the start of the school year"

wreg.com/news/memphis-h…
Image
"#Massachusetts public health officials reported 3,098 new COVID-19 breakthrough cases in fully vaccinated individuals in the past week ... 571 of breakthrough cases resulted in hospitalization ... 131 cases resulted in death"

wcvb.com/article/massac… Image
“There’s some sort of tipping point where immune evasion becomes a bigger fitness advantage than transmission”

"In the worst-case scenario, a variant could arise that would “make it like the vaccines did not exist”"

theatlantic.com/science/archiv…

Actually ADE is a worse scenario. Image
"circulation of vaccine-resistant variants is not only going to overwhelm the health care system but also pose a tremendous risk to all health care workers as the vast majority of them have already been vaccinated." —@GVDBossche

geertvandenbossche.org/post/unravelli… Image
"A UK study ...[found] that the Pfizer-BioNTech vaccine ... effectiveness fell to 74% five or six months after receiving both doses ... the Oxford-AstraZeneca vaccine showed its effectiveness fell to 67% after four to five months."

cnbc.com/2021/08/25/cov… Image
New in the @CDCgov's Morbidity and Mortality Weekly Report: "Covid-19 vaccine effectiveness [found] to be 91% from December 14, 2020, to April 10, 2021. However, in the ensuing months until August 14, 2021, this effectiveness dropped to 66%."

forbes.com/sites/brucelee… Image
#Israel: "The key finding here is that there is evidence of waning immunity from the vaccinated population."

newsweek.com/israel-covid-c…
Image
"After a decline in early summer, child cases have increased exponentially — with more than a four-fold increase in the past month ... As cases rise among children, some school leaders are pressing for precautions while others are banning mask mandates."

cnn.com/2021/08/25/hea… Image
"These findings suggest that vaccine breakthrough cases are preferentially caused by circulating antibody-resistant SARS-CoV-2 variants, and that symptomatic breakthrough infections may potentially transmit COVID-19 as efficiently as unvaccinated infections" Image
"Public health experts continue to believe that breakthrough infections are relatively uncommon"

"Scientists believe that breakthrough infections rarely result in severe illness"

“I believe in the vaccine”

nytimes.com/2021/08/26/hea…

bELiEvE sCiEnCe! 🤪
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#NorthCarolina: "I think we are seeing the most pediatric patients admitted with COVID that we have seen throughout the pandemic"

abc11.com/covid-19-in-ch…

Because #VaccinesWork! Image
#Virginia: "the 1st reported death of someone with COVID-19 who was 9 years old or younger"
nbcwashington.com/news/local/chi…

#Texas: "Houston boy between the ages of 10 & 19 is reported to be the 1st pediatric COVID-19 death without underlying health conditions"
kxan.com/news/texas/hou… ImageImage
New in Nature Communications: "our results demonstrate the escape of the emerging SARS-CoV-2 variants from neutralization by serum antibodies, which may lead to reduced protection from re-infection or increased risk of vaccine breakthrough."

nature.com/articles/s4146… Image
"universal mass vaccination will prompt dominant propagation of highly infectious, neutralization escape mutants, and naturally acquired — or vaccinal neutralizing antibodies — will no longer offer any protection to immunized individuals"

childrenshealthdefense.org/defender/pfize… Image
"AdCOVID was well tolerated but did not stimulate an adequate immune response in healthy volunteers. Altimmune will discontinue further development"

ir.altimmune.com/news-releases/… Image
India: "Bharat Biotech has now begun testing an intranasal vaccine"

"Three [now two] other countries around the world are also conducting trials for intranasal vaccines ... A̶l̶t̶i̶m̶m̶u̶n̶e̶ [👆] ... Codagenix [UK] ... Beijing Wantai Biological [China]"

firstpost.com/tech/science/b… Image
KiDs ArE lEsS aFfEcTeD! 🤪

nbcchicago.com/news/local/2-s…
texastribune.org/2021/08/27/tex…
ktla.com/news/local-new…
nytimes.com/2021/08/27/us/…
ImageImageImageImage
New in medRxiv: "78% of infections in fully vaccinated people among the [San Francisco] study were caused by variants with [antibody-resistant immune escape] mutations, compared to 48% of the cases among unvaccinated people"

mercurynews.com/2021/08/27/new… Image
"breakthrough cases are preferentially caused by circulating antibody-resistant SARS-CoV-2 variants ...symptomatic breakthrough infections may potentially transmit COVID-19 as efficiently as unvaccinated infections"

medrxiv.org/content/10.110…

tl;dr: Breakthrough=Variant Spreader Image
"A new coronavirus variant, C.1.2, has been detected in South Africa & a number of other countries ... it could be more infectious and evade vaccines ... has a mutation rate...nearly twice as fast as the current global mutation rate of the other variants"

jpost.com/health-science… Image
80% vaxxed #Singapore is changing gears towards a 'new normal'. Image
#India: "87,000 breakthrough cases ... health experts opine that the situation does not call for alarm or panic. The purpose of vaccination is not prevention of transmission, but reduction in the severity of the infection and chances of death"

newindianexpress.com/states/kerala/… Image
Worse Than Expected™ — COVID Mutation Rate Edition

New in Genome Biology and Evolution: SARS-CoV-2 "mutates almost once a week—significantly higher than the rate estimated previously ... new variants could emerge more quickly than thought previously"

phys.org/news/2021-08-m… Image
#Pennsylvania: "Among people hospitalized for the virus in the Pittsburgh region, the percentage who have been fully vaccinated ranges between 7% and 40%, doctors say, depending on the time period measured"

post-gazette.com/news/health/20…

To be clear: "between 7% and 40%" is not 99%. Image
#HerdImmunity is not happening. ImageImage
.@CDCgov: "The effectiveness of the COVID-19 vaccines against hospitalization appears to drop over time among adults over 75 ... protection against severe disease may be starting to wane among the most vulnerable Americans vaccinated earliest"

cbsnews.com/news/vaccine-e… Image
@CDCgov "#Israel has recorded its highest daily number of coronavirus cases with nearly 11,000 new infections, amid a surge caused by the highly transmissible Delta variant as schools prepare to re-open. The previous high came on 18 January, with 10,118 cases."

theguardian.com/world/2021/aug… Image
"Following a Friday announcement that Paul Stanley tested positive for the virus ... Gene Simmons has also tested positive, and [Kiss] will be postponing multiple upcoming shows ... the entire band and touring crew are fully vaccinated"

foxnews.com/entertainment/… Image
"A new coronavirus strain has been declared a variant of interest by the @WHO with mutations that may be resistant to vaccines."

The #MuVariant "has a constellation of mutations that indicate potential properties of immune escape"

newsweek.com/mu-covid-varia… Image
#Ireland: "A nursing home in the midlands has gone into full lockdown after more than a dozen residents and staff tested positive for Covid-19 ... all of the cases identified are among residents and staff who are fully vaccinated"

irishmirror.ie/news/irish-new…

Because #VaccinesWork! Image
#Massachusetts "19,443 total COVID-19 breakthrough cases in fully vaccinated people as of Aug. 31 ... That’s 3,704 breakthrough cases more than...one week earlier. Among the breakthrough cases, 651 patients have been hospitalized and 144 have died."

msn.com/en-us/health/m… Image
Unvaccinated "Rogan took to Instagram on Sept. 1 to share a message titled “I GOT COVID” ... “Monoclonal antibodies, ivermectin, Z-Pak, prednisone, everything. I also got an NAD drip and a vitamin drip ... Here we are on Wednesday, and I feel great.”

variety.com/2021/digital/n… Image
#Japan: "the #MuVariant was detected in a woman in her 40s who arrived on June 26 from the United Arab Emirates. The other case was with a woman in her 50s who arrived on July 5 from the U.K. Both women were asymptomatic upon arrival."

japantimes.co.jp/news/2021/09/0… Image
"Nine people who live in a long-term care facility in Orlando are sick with COVID-19 ... these residents were fully vaccinated ... They were showing COVID-19 symptoms and went to the hospital"

wesh.com/article/9-full…

"rare", "mild", "unlikely to be hospitalizated"! Image
#Israel, March 2021: “When 60 percent of the population is vaccinated, it's enough for the infection rate to go down.”
haaretz.com/israel-news/is…

(In fairness, they didn't actually claim that 60% vaccinated was enough for the infection rate to STAY down.) Image
March 2021: "Pfizer said its Covid-19 vaccine blocked 94% of asymptomatic infections ... at least 97% effective against symptomatic Covid cases, hospitalizations & deaths"
cnbc.com/2021/03/11/pfi…

They now say 3 boosters/year are needed.

Why should we believe anything they say? Image
#MuVariant:

"25 cases detected in North Carolina; strain could be vaccine resistant" starnewsonline.com/story/news/202…

"1 case detected in West Virginia" newstribune.info/story/news/202…

But don't worry: "Fauci: Mu COVID variant not an "immediate threat" to U.S." axios.com/fauci-mu-covid… Image
I expect that the inevitable Covid surges due to school openings will be used to further justify vaccination children. But @GVDBossche has explained that vaccinating children will only hasten the emergence of fully resistant immune escape variants.

geertvandenbossche.org/post/how-remai… Image
@GVDBossche “Unfortunately, we’re back in a position where cases, hospitalizations, and deaths are all going up and the U.K. has the highest rates of COVID in Europe, despite our superior vaccination rates" —Tim Spector, lead scientist on the Zoe COVID Study app

fortune.com/2021/08/26/sch… Image
@GVDBossche "#Israel’s national coronavirus czar on Saturday called for the country to begin making preparations to eventually administer fourth doses of the coronavirus vaccine."

timesofisrael.com/virus-czar-cal… ImageImageImage
(flat intonation) oh my god how did this happen

"Today, the Los Angeles County Department of Public Health announced the Mu variant, for the first time, has been identified in the region."

deadline.com/2021/09/mu-var…
Image
"Delta and Mu variant spreading is leading to more breakthrough cases of Covid-19"

news4jax.com/video/morning-… Image
Meanwhile, in the Valley of Fitness ...
New in Nature: "SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion"

"Compromised vaccine efficacy against the highly fit and immune evasive B.1.617.2 Delta variant warrants continued infection control measures in the post-vaccination era."

nature.com/articles/s4158… Image
The #MuVariant "first detected in South America is now running rampant across the United States - and has been detected in 42 countries."

7news.com.au/lifestyle/heal… Image
"Connecticut College does have a vaccine requirement but did not share information about the percentage of students who are fully vaccinated. Channel 3 reached out to find out how many students have been vaccinated"...but apparently did not get an answer.

wfsb.com/news/connectic… Image
"the Mu variant is highly resistant to sera from COVID-19 convalescent and BNT162b2-vaccinated individuals"

biorxiv.org/content/10.110…

#MuVariant #ImmuneEscape #SuperVariants
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"The number of patients in #Massachusetts hospitals with confirmed COVID-19 cases held at 622 ... Of those currently hospitalized, 178 are fully vaccinated"

178/622=28.6% of hospitalizations are fully vaxxed. (How many partially vaxxed, I wonder?)

nbcboston.com/news/coronavir… Image
"Zoo Atlanta is treating 13 western lowland gorillas who have tested positive for COVID-19. The gorillas were tested after they demonstrated mild coughing, runny noses and loss of appetite."

ajc.com/news/coronavir… Image
"COVID hospitalization and death increases among vaccinated people age 65 and older also appeared higher than expected, according to the CDC"

"Findings were consistent with a potential decline in vaccine protection against confirmed SARS-CoV-2 infection"

nbcnewyork.com/news/coronavir… Image
#Massachusetts: "Breakthrough cases accounted for 181 of those hospitalizations — or 29% of total COVID cases in hospitals."
masslive.com/coronavirus/20…

I imagine it's little comfort to those 181 breakthrough patients to know that they were "10 times less likely to be hospitalized". Image
Oh look - flawed logic:

"it is unlikely that vaccine-induced immunity will be the major player in variant emergence ... The modest benefit the virus would get from vaccine evasion is dwarfed by the vast opportunities to infect unvaccinated people."

scitechdaily.com/what-is-causin… Image
It's not an experiment! 🤪

“We are grateful for the cooperation between Pfizer and the Israeli Health Ministry. It is not a clinical research study. This is a non-interventional ‘real world’ evidence data collection collaboration.”

timesofisrael.com/pfizer-exec-ca… Image
"Of the 2,207 coronavirus cases recorded by the #Connecticut Department of Public Health in the most recent 7-day reporting period, 1,521 were not fully vaccinated. The remainder, 686, or 31.1 percent, had completed their vaccine series."

patch.com/connecticut/be… Image
“Variants that can beat the protection offered by vaccines are bound to emerge all over the world in the coming months and years” —David Nabarro, WHO Special Envoy for Covid-19

bloomberg.com/news/videos/20… Image
#Massachusetts: "4,415 more breakthrough cases since last Tuesday’s report. A comparison of the seven-day report to the most recent seven days worth of new cases shows that approximately 40% of new cases are among those who are fully vaccinated."

masslive.com/coronavirus/20… Image
"escape mutants are able to infect even the vaccinated ... the vaccinated that do have breakthrough infections [may be] walking around feeling relatively healthy and yet producing and shedding just as much virus" —@RWMaloneMD, speaking with @jimmy_dore

"The whole policy is poorly thought out ... these people are [either] grossly incompetent, or their decisions are being inappropriately influenced." —@RWMaloneMD, speaking with @jimmy_dore

#RegulatoryCapture
@RWMaloneMD @jimmy_dore @jimmy_dore: "What does 'leaky' mean?"

@RWMaloneMD: "No vaccine is perfect. But this one is particularly imperfect, in that the protection...is modest... and going down as the virus evolves .... that's never going to get us to herd immunity"

@RWMaloneMD @jimmy_dore "Lab test results have showed that COVID-19 caused the deaths of two beavers in Mongolia ... another seven beavers of the center have tested positive for the virus ... the beavers may have contracted the virus from their ranchers"

dimsumdaily.hk/mongolia-confi…

#AnimalReservoir Image
@RWMaloneMD @jimmy_dore "it means vaccines should be banned, not mandated. it means boosters are a societal risk accelerator not an attenuator. it means that adults do not need to be shielded from school kids, it means that school kids need to be protected from vaccinated adults" Image
Smithsonian’s National Zoo in Washington, D.C.: "a group of African lions, along with a Sumatran tiger and two Amur tigers, were positive for COVID-19 in initial tests based on fecal samples, with final results expected in the next few days."

thehill.com/blogs/blog-bri… Image
"even asymptomatic, fully vaccinated people might shed infectious virus ... these data indicate that vaccinated and unvaccinated individuals infected with the Delta variant might transmit infection."

medrxiv.org/content/10.110… ImageImage
@GVDBossche, FAQ #23, May 2021: "asymptomatically infected vaccinees will be more likely to shed ‘more infectious’ variants ... than non-vaccinated, asymptomatically infected subjects"


Riemersma et al., medRxiv, August 2021:
30% of current #Massachusetts hospitalizations are fully vaccinated.

wwlp.com/news/health/co…
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"Corporate media companies, from the New York Times and BBC to Facebook and Youtube – many of them invested in pharmaceuticals themselves – are deciding that you shouldn’t even know that the Covid vaccines are leaky, let alone the potential pitfalls." Image
"There is no more reason to believe that [scientists who best know about leaky vaccines employed by the vaccine companies] will whistleblow on the pharmaceuticals industry than the scientists who worked for the fossil fuel industry ..." —@Jonathan_K_Cook

jonathan-cook.net/blog/2021-09-1… Image
"a leaky vaccine has never before been used in the midst of a global pandemic. This is uncharted territory." —@Jonathan_K_Cook

jonathan-cook.net/blog/2021-09-1…
Image
@Jonathan_K_Cook "This is precisely not the time for lazy assumptions, group-think, censorship or standing back as the corporate media decides which experts should be allowed to be part of the public conversation."
#Singapore: "1,009 new infections on Saturday, and 1,012 new cases on Sunday ... more than 80% of Singapore’s population has already been vaccinated"

cnbc.com/2021/09/20/sin…

"New Normal"?
Image
"A new mutation of the Delta variant which could make it more resistant to vaccines has been identified in the UK ... suggests the virus is coming under pressure in a largely vaccinated population in the UK and is trying to adapt to survive"

inews.co.uk/news/politics/… Image
"We can expect a switch towards evolution really being driven for immune escape and antigenic drift. This degree of evolvability we've seen so far, to me, suggests that we can expect a fairly rapid pace of antigenic drift in the future."

"Can a vaccinated young person who is socially active transmit the virus to a vaccinated elderly person?"

Yes.

clickondetroit.com/health/2021/09…
Image
New in Clinical Infectious Diseases: "people who contract [Covid] through the Alpha variant of SARS-CoV-2, exhale “43 to 100 times” more virus into the air than those infected with its original strains"

hindustantimes.com/world-news/cov… Image
"Mild cases of COVID-19 among vaccinated individuals are becoming increasingly common ... but physicians and public health experts say that shouldn’t be a cause for significant concern."

rollcall.com/2021/09/22/bre…

*provided you ignore natural selection. Anyway, so much for "rare". Image
#Israel: "If the vaccine is preventing hospitalisations, then the rate of hospitalisations per positive test rate should have fallen dramatically relative to history. Has it? Here is the data. Short answer: no ... what about deaths per positive test rate? No clear impact here." Image
"The R.1 variant, now in Georgia, was first detected in the US in a Kentucky nursing home in March ... infected 25% of the vaccinated residents."

“That’s the first warning, that there was a virus that spreads through a fully vaccinated population”

11alive.com/article/news/h… Image
"That is the major concern about these breakthrough cases. The 𝘀𝗽𝗿𝗲𝗮𝗱 𝗳𝗿𝗼𝗺 𝘁𝗵𝗲 𝘃𝗮𝗰𝗰𝗶𝗻𝗮𝘁𝗲𝗱 𝘁𝗼 𝘁𝗵𝗲 𝘂𝗻-𝘃𝗮𝗰𝗰𝗶𝗻𝗮𝘁𝗲𝗱, who will get sicker."

abc7ny.com/covid-vaccine-…


"Pandemic of the unvaccinated" Image
"A comparison of age adjusted all-cause mortality rates in England between vaccinated and unvaccinated"

"It turns out that, even using this age adjusted mortality rate, the death rate is currently higher among the vaccinated than the unvaccinated."
Image
"The vaccinated are actually higher risk for becoming super-spreaders. Because they're replicating virus at the same or higher levels as the unvaccinated, but they feel better, so that means they're more likely to be out in the community." —@RWMaloneMD

@RWMaloneMD "The most important thing to do ... is to reduce infectious pressure ... How can we reduce it? Well, first of all, we have to stop this mass vaccination ... the worst thing ever is to vaccinate younger age groups ... this is the buffer!" —@GVDBossche
@RWMaloneMD @GVDBossche @RWMaloneMD on original antigenic sin and high-zone tolerance.

"As we look forward in vaccine policy there's the assumption that more is better. That's not true with vaccines."
@RWMaloneMD @GVDBossche "I also predicted that, first it would primarily affect the vulnerable people, the elderly, but then the virus would come back and hit also increasingly younger age groups, which is what we are seeing right now. So it's pretty much in line with what I predicted." —@GVDBossche
@RWMaloneMD @GVDBossche "the Israeli data are not only concerning to me, I think they're concerning to the US government right now" —@RWMaloneMD
"Breakthrough patients in #Guam account for about 40% of hospital admissions. The Covid surge is perplexing for a territory with a vaccination rate close to 90%, ranking sixth in the US."

theguardian.com/world/2021/sep… Image
"Over 20% of positive, vaccinated individuals had low Ct-values (<20) [indicative of high viral loads], a third of which were asymptomatic"

"asymptomatic vaccinated individuals may increasingly contribute to the ongoing pandemic as the proportion of vaccinated individuals grows"
“This communication … challenges the assumption that high universal vaccination rates will lead to herd immunity and prevent COVID-19 outbreaks… In the outbreak described here [Israel, July 2021], 96.2% of the exposed population was vaccinated.”

eurosurveillance.org/content/10.280… Image
"Hospitals across most New England states are seeing full intensive care units & staff shortages as growing coronavirus cases continue to shake the region ... full vaccination rates across the six New England states ranging from a high of 69.4% to 61.5%"

axios.com/coronavirus-pa… Image
"We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11–July 29, 2021. This mutation appears to affect immune response and vaccine efficacy; monitoring its appearance is urgent."

wwwnc.cdc.gov/eid/article/27…

#ImmuneEscape Image
"A Virginia family is trying to process how their 10-year-old daughter went from being perfectly healthy to dying in five days from Covid-19 ... Her parents...are vaccinated along with their two older sons."

cnn.com/2021/10/04/us/… Image
New in The Lancet - Retrospective S. California cohort study finds Pfizer vaccine "Effectiveness against infections declined from 88% during the first month after full vaccination to 47% after 5 months."

thelancet.com/journals/lance… ImageImage
Dr. John Campbell: "Doubly-vaccinated people [in the #UK] are clearly getting infected. In the fully vaccinated population over 14,000 new cases per day"



*Those are just the symptomatic cases; there are almost certainly uncounted asymptomatic cases too.
"What we're doing with universal vaccination is driving towards this endpoint of vaccine-resistant mutants." —@RWMaloneMD
"In July the majority of my sicker patients were unvaccinated. And then I noticed in August it seemed to be about 50-50. And now I'm noticing it's more vaccinated. And so ... a very quick change in my practice." —Dr. Heather Gessling

full video: 3speak.tv/watch?v=pandem…
Qatar (76% fully vaxxed): "BNT162b2-induced protection against SARS-COV-2 infection appeared to wane rapidly following its peak after the second dose, but protection against hospitalization and death persisted at a robust level for 6 months"

nejm.org/doi/full/10.10… Image
Q: "Can we vax our way out of this? Is that possible?"

A: "You can vaccinate the whole world with [the current leaky vaccines] and you still won't stop the spread. What you will do is select for even more potent escape mutants"

3speak.tv/watch?v=pandem…
New in NEJM: "Pfizer's immunity effectiveness declines steadily, hovering at around 20% after the four-month mark"

nejm.org/doi/full/10.10…
yahoo.com/news/pfizers-c… Image
#Pennsylvania: "In September, 26% of the nearly 5,000 people hospitalized with COVID-19 were vaccinated, the @PAHealthDept said. That’s up from prior estimates from health systems, which stated about 10% of people hospitalized with COVID-19 had gotten the vaccine." Image
@PAHealthDept "Rounding out the top 5 most prevalent lineages [in Nevada] are four mutants of delta — AY.4, AY.25, AY3 and AY13 — accounting for 29% of genetically sequenced cases. “These sublineages — there’s more than just AY.26 — are really taking over”"

reviewjournal.com/news/politics-… Image
@PAHealthDept "The first stages of this evolution [towards immune escape variants that are fully resistant to the vaccines] is what we now begin to see in countries which have already massively vaccinated their population"

geertvandenbossche.org/post/the-last-… Image
@PAHealthDept @GVDBossche, June 2021: "there is ... one certainty, which is that Sars-CoV-2 𝘃𝗮𝗿𝗶𝗮𝗻𝘁𝘀 𝗮𝗿𝗲 𝗿𝗮𝗽𝗶𝗱𝗹𝘆 𝗲𝘃𝗼𝗹𝘃𝗶𝗻𝗴 𝗶𝗻 𝗿𝗲𝘀𝗽𝗼𝗻𝘀𝗲 𝘁𝗼 𝘁𝗵𝗲 𝗻𝗮𝘁𝘂𝗿𝗮𝗹 𝗶𝗺𝗺𝘂𝗻𝗲 𝘀𝗲𝗹𝗲𝗰𝘁𝗶𝗼𝗻 𝗽𝗿𝗲𝘀𝘀𝘂𝗿𝗲 they are experiencing"

geertvandenbossche.org/post/why-the-o… Image
@PAHealthDept @GVDBossche "this is an awful lot of puzzle pieces snapping together and i think we’re really starting to see what this is a picture of. leaky vaccines that stop severe illness and death but not spread look to be affecting the evolution of the covid 19 virus." Image
"it’s the virus adapting to a stressor we put on it and becoming much more dangerous as a result ... everyone is harmed but the brunt is borne by the unvaccinated which perversely winds up looking like better vaccine efficacy"

boriquagato.substack.com/p/are-leaky-va…
This seems important.

#Singapore.

ImageImageImage
"This virus has taken a painful toll on both the vaccinated and unvaccinated over the past few months, a phenomenon that is very well explained with a leaky vaccine that fails to sterilize the virus but causes viral immune escape and a degree of vaccine mediated enhancement." Image
"The reality is that more people have died from COVID-19 in 2021, with most adults vaccinated (and nearly all seniors), than in 2020 when nobody was vaccinated. Something is not adding up"

theblaze.com/op-ed/horowitz…
"what one would expect if a virus were undergoing vaccine mediated evolution ... and selecting for hotter strains because vaccinated people can carry and spread them and not die ... CFR on delta is nearly 7X what it was in the beginning of june"

boriquagato.substack.com/p/are-leaky-va… Image
"unexpected"?


"the trend line suggests a marginally positive association such that countries with higher percentage of population fully vaccinated have higher COVID-19 cases per 1 million people" Image
bUt, BuT, wHeRe Is HeRd ImMuNiTy?!?



(Spoiler: Dr. Campbell remains bewildered by the pandemic dynamics, and unable to reliably distinguish between correlation and causation.)
@chrismartenson breaks down the recent paper entitled "Increases in COVID-19 are unrelated to levels of vaccination across 68 countries and 2947 counties in the United States"

"Pretty sure that's not how this is supposed to be working. At all."

@chrismartenson "#Singapore's health ministry reported 3,994 new cases of COVID-19 on Tuesday, the highest since the beginning of the pandemic ... More than 80% of Singapore's population has been vaccinated against the virus."

reuters.com/world/asia-pac… Image
@chrismartenson Albany County, New York: "From September 8 to October 19 the percentage of vaccinated people who caught COVID was between 43-49%"

news10.com/news/percentag…
Image
"AY.4.2 has been spotted in the UK, Germany, Denmark and the US to date ... Experts estimate that AY.4.2 is up to 15 per cent more infectious than the Delta variant."

todayuknews.com/health/time-la…
Image
"the British experience shows that, in the face of the highly transmissible Delta variant of the coronavirus, herd immunity is elusive"

wsj.com/articles/covid…

'elusive' 🤔
Image
"Coronavirus infections and deaths in #Ukraine surged to all-time highs on Thursday ... Authorities have blamed [without evidence * ] a spike in infections on a slow pace of vaccination"

euronews.com/2021/10/21/ukr…

* "Increases in COVID-19 are unrelated to levels of vaccination" ⬇️ Image
"Among [the 16 Covid deaths reported Thursday in #Singapore], eight had not been vaccinated against Covid-19, one was partially vaccinated and the remaining seven were fully vaccinated."

todayonline.com/singapore/3439…

(7/16=44%) Image
Reminder: "The worst thing that could happen is that we start vaccinating our children." —@GVDBossche

@GVDBossche "AY.4.2 has now been identified in four states—North Carolina, Massachusetts, Washington and California—in addition to the District of Columbia, as of October 21"

newsweek.com/delta-sub-vari… Image
New in MedRxiv: "Breakthrough SARS-CoV-2 infections in 620,000 US Veterans" medrxiv.org/content/10.110…

"By August, protection against infection had declined to: 3% (95% CI, -7% to 12%) for Janssen; 64% (95% CI, 62%-66%) for Moderna; and 50% (95% CI, 47% to 52%) for Pfizer-BioNTech" Image
Dr. Campbell tells a pretty story about 'endemic equilibrium' in this video. His fairy tale includes lots of false assumptions and evidence-free assertions, and of course it has a happy ending! 🤪

"What I'm expecting in Israel [and in other highly vaccinated countries, like the UK] is that this movement of waves will come down ... you will end up with this high plateau ... and then, what I expect, is a huge wave." —@GVDBossche



Repeat: "huge wave"
@GVDBossche New in Cell. & Mol. Immun.: "our results suggest that the SARS-CoV-2 variant A.30 can evade control by vaccine-induced antibodies and might show an increased capacity to enter cells in a cathepsin L-dependent manner, which might particularly aid in the extrapulmonary spread" Image

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More from @DavidLWindt

David Windt Profile picture
10 Oct
"Love me, I'm a Liberal", Phil Ochs (1966)



*Except these days, they're far more than "10 degrees to the right of center if it affects them personally"
"totalitarian systems...represent a kind of collective psychosis ... reason and common human decency are no longer possible ... There is only a ... projection of the enemy imagined to be 'in our midst'. Thus society turns on itself"

Read 4 tweets
David Windt Profile picture
29 Sep
"The oligarchs from the establishment Republican Party [e.g., Liz Cheney, Mitt Romney, George and Jeb Bush] have joined forces with the oligarchs in the Democratic Party to defy the autocrats in the new Republican Party who have coalesced in cult-like fashion around Donald Trump" Image
"The liberal class, fearing autocracy, has thrown in its lot with the oligarchs, discrediting and rendering impotent the causes and issues it claims to champion.
"Oligarchies, which spew saccharine pieties and platitudes, engage in lies that are often far more destructive to the public than the lies of a narcissist autocrat."
Read 4 tweets
David Windt Profile picture
7 Sep
"informational flooding, well known to experts in the science of internet propaganda"
"The fact that Ivermectin is so much SAFER than over-the-counter Tylenol should make you wonder exactly why these articles made the news. The reason is simple. Pfizer and Merck are getting ready to launch expensive new anti-viral pills"
"Merck, more than anyone, knows Ivermectin to be safe as they developed this drug and used it in over three billion doses IN HUMANS in the Mectizan Program to eradicate River Blindness ... Merck sold us out for precisely 1.2 billion pieces of silver."
Read 6 tweets
David Windt Profile picture
29 Aug
#MassPsychosis: "An epidemic of madness that occurs when a large portion of society loses touch with reality and descends into delusions ... the individuals who make up the infected society...become more unreasonable, irresponsible, emotional, erratic, and unreliable"
"A psychotic break is not a descent into a state of greater disorder, as many believe, but a reordering of one's experiential world which blends fact and fiction, or delusions and reality, in a way that helps end the feelings of panic ...at the cost of losing touch with reality."
"totalitarian systems...represent a kind of collective psychosis ... reason and common human decency are no longer possible ... There is only a pervasive atmosphere of terror and a projection of the enemy imagined to be 'in our midst'. Thus society turns on itself"
Read 4 tweets
David Windt Profile picture
18 Aug
@arimoin cAn YoU iMaGiNe HoW mUcH wOrSe He'D bE iF hE wAsN't VaCCinAtED?!? 🤪
Is the science too hard to follow? Don't worry about it! Just remember that #VaccinesWork!

#BelieveScience 🤪

Image
40% of Onondaga County, #NewYork positive cases since July 1 are "fully vaccinated. Does that mean the vaccines aren’t working? No ... Vaccines...are aimed at keeping people from getting severely ill — and they’re doing that."

syracuse.com/coronavirus/20…

#MovingTheGoalPosts Image
Read 76 tweets
David Windt Profile picture
18 Aug
"Empires at the end are collective suicide machines."
"The military becomes in late empire unmanageable, unaccountable, and endlessly self-perpetuating, no matter how many fiascos, blunders and defeats it visits upon the carcass of the nation, or how much money it plunders"
"Nearly all the roughly 70 empires during the last four thousand years, including the Greek, Roman, Chinese, Ottoman, Hapsburg, imperial German, imperial Japanese, British, French, Dutch, Portuguese, and Soviet empires, collapsed in the same orgy of military folly."
Read 4 tweets

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