Tyler Black, MD Profile picture
Sep 3, 2021 10 tweets 5 min read Read on X
THREAD: #astrophotography "stacking"

If you're following me you've seen pictures of amazing nebulas and galaxies from space.

How can I take this dark portion of the sky and get a nebula out of it? From the ground? From light-polluted Vancouver?!

Physics to the rescue! /1
In #Astrophotography, cameras & randomness of light sources in space filtering through the atmosphere produce noise.

But! The photons of space are there! So we do something called "Stacking".

Here is one 90-second exposure of the Iris Nebula. EW! barely looks like anything. /2
However, here is 5 x 90s images stacked together. as the noise is random, and the signal coming from space is constant, as we add more images, we start being able to separate the signal from the noise.

See how there is more nebula visible now? /3
We're at 10 x 90s images.

The random noise keeps averaging out on top of itself (decreasing the noise), whereas the signal is constant!

Noise down, signal same = increasing the signal-to-noise ratio!

Now we start seeing details within and outside the nebula. /4
13 x 90s images.

When we started, the noise was much higher, but with each 90 second image added, the noise decreases. At this point, it's precisely half what it was before.

You'll note the light parts are getting *very smooth*. The noise is weak compared to strong signal. /5
20 x 90s images (30 minutes)

The gains start becoming smaller, so the time invested needs to increase. Our signal to noise ratio inches higher and higher. (2.5x better now!)

Despite the minor minimal gains, we are starting to see more "space dust" outside the nebula! /6
40 x 90s images (60 minutes)

We've gone from 2.5x better to 3.3x better, and we're getting even more detail of the dust clouds surrounding the Iris Nebula. /7
And here we are at 240 images!

Of course it is not processed yet so it still looks noisy, but now we have tons of definition within the nebula, as well as more than a few surrounding dust clouds. /8
Side by side, you can see what a difference stacking makes. By the time I'm at 6 hours, woah! huge difference. /9
So future/present astrophotographers! check out some videos/tutorials on stacking! It's a great way to get that exposure time up while keeping thermal noise low (for uncooled cameras), and it is essential for deep space photography. /10

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More from @tylerblack32

May 5
RFK is no better at psychiatric medications than he is about vaccines.

RFK's "overmedicalization crisis" thread is a master class in using true-ish numbers to imply a false conclusion. Let's go through it. 🧵

/1
The core trick: he treats prescription prevalence as self-evidently bad. But high rates only signal a problem if the meds don't work, are given to people who don't need them, or cause net harm. He establishes none of this. He just gestures at numbers.

/2
The same rhetorical structure would indict insulin prescribing, or asthma inhalers. Prevalence is not pathology. The question is whether treatment matches need — and whether the alternative (untreated illness) is better or worse.

/3
Read 20 tweets
May 4
Disabled people should not live in poverty.

It makes no sense the way we treat our people with disabilities in Canada. Canada has the full apparatus to implement adjusted payments, yet we typically support disabled people WELL under the poverty line.

/1 Image
Canada has an official poverty line: the Market Basket Measure. It's regionally calibrated, methodologically sound, and updated by StatCan.



A single person on BC PWD receives ~$18.4k/year. The Vancouver MBM is ~$29k.

/2www150.statcan.gc.ca/t1/tbl1/en/tv.…
That's not a rounding error. It's a structural choice.

PWD recipients in Vancouver sit at roughly 47% of the poverty line and below the Deep Income Poverty threshold (75% of MBM), which is the level StatCan uses to flag the worst material deprivation in the country.

/3
Read 10 tweets
May 2
Quick thread: "How do SSRI's work" 🧵

I've had a few patients ask me how SSRI's work.

To be clear, my first answer is "well we know they are supposed to block serotonin reuptake, but it's not that simple and we don't really know."

But, if you want the best 2026 science...

/1Image
For a few particularly science-interested patients, I walk them through what we currently have for the 'best evidence' even though we're still not sure.

This is the "best story" I can tell about SSRI's right now.

(nb, this is NOT locked in, this is MY best synthesis)

/2
1) SSRIs BLOCK the Serotonin Transporter
The protein that pulls serotonin back into the neuron after its released is blocked. Serotonin lingers longer in the synapse, the gap where neurons signal each other.

This is very well established, & how SSRIs were designed.

/3Image
Read 15 tweets
May 2
The Ihben story is making the rounds. "Judge forced 18 vaccines, child got autism." It's being treated as a smoking gun. It is not a smoking gun. It is barely a story.

/1
Sourcing: one father, one advocacy org (CHD), one GiveSendGo. Records sealed. No filings. No named physicians. Every outlet repeating it cites the same Defender article. This is a closed loop, not corroboration.

/2
"18 vaccines in one day" is not a thing. That number counts antigens as doses to make the headline scream. Real catch-up schedules don't work this way and you can verify that in five minutes on the CDC site.

/3
Read 10 tweets
Apr 30
🧵Borderline Personality Disorder (BPD) 🧵

Ask any person who has been even suggested to have BPD; they will uniformly tell you that they have been told to try DBT (Dialectical Behavioural Therapy). Reflexively recommended. "Gold standard."

This is not science-supported.

/1Image
Quick history: Marsha Linehan developed DBT in the late 1980s, published the foundational manual in 1993. She drew on CBT, Zen Buddhism, and dialectical philosophy. Brilliant clinician, brilliant marketer. Her institute has trained tens of thousands of therapists worldwide.

/2 Image
That marketing machine is the reason DBT is "the BPD treatment." It is not the reason DBT works better than alternatives, because it does not.

The faint superiority signals in older trials evaporate once you adjust for allegiance bias (DBT researchers studying DBT).

/3
Read 16 tweets
Apr 30
The McCullough Foundation's @NicHulscher — who posts garbage medical misinformation — styles himself an "independent epidemiologist."

His entire career has been spent publishing with, and working for, McCullough. Image
No academic post, no health agency, no clinical role, no pre-Foundation experience. Hired straight out of his 2024 MPH by the senior author on nearly every paper bearing his name.

/2
He publishes almost exclusively with McCullough, overwhelmingly in predatory or fringe journals, and has already been retracted twice — plus an Expression of Concern — in a career that's barely two years old.

/3
Read 7 tweets

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