Richard H. Ebright Profile picture
Sep 7, 2021 10 tweets 2 min read Read on X
"NEWLY RELEASED documents provide details of US-funded research on..coronaviruses at the Wuhan Institute of Virology..The Intercept has obtained more than 900 pages of documents detailing..work of..EcoHealth Alliance..at the Chinese lab.."

interc.pt/3yN1YIj
"The trove of documents includes two previously unpublished grant proposals that were funded by the NIAID, as well as project updates relating to the EcoHealth Alliance’s research, which has been scrutinized amid increased interest in the origins of the pandemic."
The materials show that the 2014 and 2019 NIH grants to EcoHealth with subcontracts to WIV funded gain-of-function research as defined in federal policies in effect in 2014-2017 and potential pandemic pathogen enhancement as defined in federal policies in effect in 2017-present.
(This had been evident previously from published research papers that credited the 2014 grant and from the publicly available summary of the 2019 grant. But this now can be stated definitively from progress reports of the 2014 grant and the full proposal of the 2017 grant.)
The materials confirm the grants supported the construction--in Wuhan--of novel chimeric SARS-related coronaviruses that combined a spike gene from one coronavirus with genetic information from another coronavirus, and confirmed the resulting viruses could infect human cells.
The materials reveal that the resulting novel, laboratory-generated SARS-related coronaviruses also could infect mice engineered to display human receptors on cells ("humanized mice").
The materials further reveal for the first time that one of the resulting novel, laboratory-generated SARS-related coronaviruses--one not been previously disclosed publicly--was more pathogenic to humanized mice than the starting virus from which it was constructed...
...and thus not only was reasonably anticipated to exhibit enhanced pathogenicity, but, indeed, was *demonstrated* to exhibit enhanced pathogenicity.
The materials further reveal that the the grants also supported the construction--in Wuhan--of novel chimeric MERS-related coronaviruses that combined spike genes from one MERS-related coronavirus with genetic information from another MERS-related coronavirus.
The documents make it clear that assertions by the NIH Director, Francis Collins, and the NIAID Director, Anthony Fauci, that the NIH did not support gain-of-function research or potential pandemic pathogen enhancement at WIV are untruthful.

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More from @R_H_Ebright

Apr 23
"Antibiotic development is challenging: the process can take 10 to 15 years and cost…$1 B…With antimicrobial resistance…estimated to cause 1.2 M deaths…per year, we need to ensure that new antibiotics are not only being developed but also…used"

acpjournals.org/doi/10.7326/M2…
"[D]espite the development and regulatory approval of 7 new antibiotics active against multidrug-resistant gram-negative bacteria in the last 10 years, uptake of these antibiotics has been slow."
"[U]tilization o…next-generation antibiotics, including meropenem–vaborbactam, eravacycline, imipenem–cilastatin–relebactam, and cefiderocol was…low…, with no [!!!] documented use of plazomicin."
Read 7 tweets
Apr 20
"With the current level of action, it is projected that antimicrobial resistance (AMR) will lead to significantly higher healthcare costs, with annual expenses for treating resistant bacterial infections estimated to reach US $412 billion worldwide."

amrleaders.org/resources/m/it…
Image
"The increase in morbidity and mortality resulting from these bacterial infections [also] will have secondary effects, resulting in losses of approximately US $443 billion annually from reduced workforce participation alone."
"Evaluation of a package of...interventions—including awareness raising, surveillance, stewardship in human and animal health, infection prevention, and new treatments—suggests that there is potential to avert nearly US $7.7 trillion in losses...by 2035."
Read 5 tweets
Apr 20
"The FBI was tipped off in April 2020 to gain-of-function virus research in China, funded by the agency formerly headed by Dr. Anthony Fauci, that 'would leave no signature of purposeful human manipulation,' emails from agents at the bureau show."

nypost.com/2024/04/19/us-…
"At least one FBI agent at the bureau’s Newark Field Office referred to the revelation as 'alarming.'"

"The five-pages of emails were obtained...via a FOIA request and released Friday."
"'These smoking gun documents showed the FBI quickly understood that Fauci’s agency funded the gain-of-function research that could disguise the resulting coronavirus as 'natural,' Judicial Watch President Tom Fitton said"
Read 7 tweets
Apr 20
""The FBI was tipped off in April 2020 to gain-of-function virus research in China, funded by the agency formerly headed by Dr. Anthony Fauci, that 'would leave no signature of purposeful human manipulation,' emails from agents at the bureau show."

nypost.com/2024/04/19/us-…
"At least one FBI agent at the bureau’s Newark Field Office referred to the revelation as 'alarming.'
"The five-pages of emails were obtained...via a FOIA request and released Friday."
Read 8 tweets
Apr 16
"The…Proximal Origins paper that dismissed the plausibility that COVID…resulted from a research-related incident sits among the most consequential failures of scientific integrity…I have seen in…30 years working on science and technology policy."

open.substack.com/pub/rogerpielk…
Image
"The production, publication, and post-publication treatment of…'Proximal Origins'…represents a major failure of scientific integrity by its authors, its unacknowledged ghost contributors (including U.S. government officials), and the academic journal that published it."
"In their roles contributing to the coordination of Proximal Origins, US government officials, specifically Dr. Anthony Fauci and Dr. Francis Collins,[ likely violated the Scientific Integrity Policies of the Department of Health and Human Services."
Read 5 tweets
Apr 4
"During his closed-door transcribed interview with the Committees on November 14, 2023, Dr. Daszak made multiple statements inconsistent with documents and evidence reviewed by the Committees."
House letter cites examples of false Comgressional testimony provided by Daszak

d1dth6e84htgma.cloudfront.net/2024_04_04_SSC…
"On November 14, 2023, you testified at a transcribed interview before the Committees…At the interview, committee counsel advised that…if you knowingly made false statements, you could be subject to criminal prosecution."
Read 7 tweets

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