- Moderately infectious (ie infect 2 or 3 ppl in a classroom): 90-95%
- Mildly infectious (ie spread to spouse only) ~80-90%
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This Graph of viral load over time helps to explain this sensitivity issue:
Further, symptoms vs no symptoms has no impact on test performance. Studies that say it does are not recognizing the sampling bias that enters their studies.
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Here we go again with this asinine cautious approach to testing for H5N1
CDC is NOT recommending that people with no symptoms - but who have had contact w infected animals - be tested at all… and certainly are not recommending a swab w any frequency.
Though we should have learned it in 2020, Here’s why this doesnt make sense:
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Firstly, tests are our eyes for viruses. It’s literally how we see where viruses are
If we wait until people are getting sick, we may have missed a major opportunity to find viruses jumping into humans before they learn to become so efficient in us that they cause disease
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So waiting until we actually have highly pathogenic strains harming humans - when we have a pretty discreet population at the moment to survey - is short sighted
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A particularly deadly consequence of measles is its erasure of previously acquired immune memory - setting kids and adults up for infections that they shouldn’t be at risk from!
We found for example that measles can eliminate as much as 80% of someone’s previously acquired immunity to other pathogens! science.org/doi/full/10.11…