Hey, y'all.. I deleted my earlier tweet relaying a concern that #Molupiravir might also mutagenize our own DNA. Why did I delete it? Because I was wrong. An expert who I absolutely trust DM'd me to say the following: 🧵 (TL;DR: my concern is unfounded)
"People don’t realize how much sequencing & safety studies have been done just to get to this point. And it is far far less mutagenic (if at all) than the deoxy nucleotide analogs that have been used long-term for HIV patients for decades!"
My colleague added: "Molnupiravir is only used temporarily and has a short window of therapeutic efficacy (as for any respiratory pathogen drug). This will be more life saving for flu treatment than oseltamivir when it gets finally approved for flu." #AntiviralsWork
It's really important that we follow the science & trust the people who actually have real data & experience working with viruses, antivirals, vaccines, antibodies, et cetera. #Misinformation is already HUGE problem. I don't want to contribute to mistrust of an effective drug.
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