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Bobby Rajesh Malhotra ツ ψ Profile picture
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12 Oct, 153 tweets, 109 min read
Quote: "[.] populations that received mRNA vaccines according to standard EUA intervals, our data suggest that vaccine effectiveness against any symptomatic disease is considerably lower against the delta variant and may wane over time since vaccination."

nejm.org/doi/full/10.10… Image
"Breakthrough Infections of SARS-CoV-2 Gamma Variant in Fully Vaccinated Gold Miners, [.]"

Illustrates importance of allowing infection and natural broader immunity of low-risk people, to reduce variant circulation and protect the vulnerable vaccinated.

wwwnc.cdc.gov/eid/article/27… Image
"Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity"

"Natural immunity affords longer lasting & stronger
protection [.] compared to BNT162b2 two-dose immunity."

Spike-only focus=#fail.
Natural immunity 🎯 M & N Protein. #BigPharma=#noobs?
medrxiv.org/content/10.110… Image
Snowflake @trvrb is noobing around too. Doesn't properly cover the alarming S1 mutational dynamics: "muuh, something is wrong with preinfection immunity here". Admits: any rate above "1" is unlikely, then debunks himself with his own @nextstrain data. LOL.
biorxiv.org/content/10.110… ImageImageImageImage
"Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans"

"[.] preexisting memory CD4+ T cells that are cross-reactive [.] to SARS-CoV-2 & the common cold coronaviruses human coronavirus (HCoV)-OC43, HCoV-229E, HCoV-NL63, & HCoV-HKU1."
ncbi.nlm.nih.gov/pmc/articles/P… ImageImageImageImage
"Shedding of Infectious SARS-CoV-2 Despite Vaccination when the Delta Variant is Prevalent"

"in 93% of samples with Ct <25 indicates that high viral loads are consistent with the potential to transmit SARS-CoV-2, regardless of the [.] vaccination status."
medrxiv.org/content/10.110… ImageImage
Special thanks to @jjcouey for his outstanding work. Follow him. Read his outstanding wrap-up on the #BigPharma-fail of the Century - non sterilizing Spike-only focus that has led to an unprecedented global clusterfuck concerning rational health policies. img1.wsimg.com/blobby/go/e89c… Image
In the art & science project #allesaufdentisch @Kevin_McKernan also discusses with me about much better future outlooks than the narrow Spike-only focus that has blinded all fields of Life Sciences and has led us to an orthodox T-Cells/B-Cells Ignorance.
Join my telegram channel for more in depth resources & discussions (in the comments-group). t.me/bobbynetwork
Addendum: "Robust T Cell Immunity in Convalescent Individuals with Asymptomatic or Mild COVID-19"

At The Heart Of It All.

Final Conclusion: Natural Immunity, consequently natural evolution doesn't care about the Spike, only #BigPharma does. I wonder why.
pubmed.ncbi.nlm.nih.gov/32979941/ ImageImage
Addendum #2: Now @AlbertBourla will muuuh about: "Buu...buuu....buuut muuuuuuuuh Booosters muuuh".

Answer: Nope, Albert, nope, you are a shitty noob.

Add. #3: "But muuh Bobby, why are you shilling for natural immunity?"
Answer: Trillions of Spike can affect your B Cell Memory roster of all the other human betacoronavirions, this immunity is cross reactive. All of a sudden your body is focusing on an outdated 2020 Spike: #Fail. Image
Add.#4: "But muuh Bobby, that meme above is offensive."
Answer: True, but we are in a memetic warfare. Political incorrectness serves as an ActionJacksonTrigger to rethink the overall divide et impera. Have another political incorrect meme in case @GVDBossche was right all along. Image
Add.#5: Quote: "Here are 40 more...", which I'll cover in detail within this thread or as an extra Immunology 101 thread overview. Thx 2 @Ayachuco1 for pointing out.

threadreaderapp.com/thread/1427606…
Add.#6:
Add.#7
Add.#8: "Waning of BNT162b2 vaccine protection [.] in Qatar"

"[.] BNT162b2 effectiveness [.], [.] in the 1st 5 weeks after the 2nd dose. [.], with the decline accelerating ≥15 weeks [.], reaching diminished levels of protection by the 20th week."

medrxiv.org/content/10.110… Image
Add.#9:

"(CNN)Vaccination alone won't stop the rise of new variants and in fact could push the evolution of strains that evade their protection, researchers warned Friday."

edition.cnn.com/2021/07/30/hea…
Add.#10: Image
Add.#11: "Comparing SARS-CoV-2 natural immunity to vaccine-induced immunity: reinfections versus breakthrough infections"

Vaccinated subjects had 13 times higher risk of new infection (Delta) VS natural immunity, 7x more likely to seek hospitalization.
medrxiv.org/content/10.110… Image
Add.#12: "Reanalysis of [.] BNT162b2 SARS-CoV-2 vaccine data fails to find any increased efficacy following the boost: Implications for vaccination policy and our understanding of the mode of action"

"no additional benefit from a 2nd vaccination".

medrxiv.org/content/10.110… Image
Add.#13: Quick reminder & ignore the "booster"-shilling.
Add.#14: PAGE 23: "recent observations from UK Health Security Agency (UKHSA) surveillance data that N antibody levels appear to be lower in individuals who acquire infection following 2 doses of vaccination"

assets.publishing.service.gov.uk/government/upl… Image
Add.#15
Add.#16: Correlation between % of population fully vaccinated & new COVID-19 cases in the last 7 days. Trend line suggests a marginally positive association such that countries with higher % of fully vaccinated have higher COVID-19 cases/1 million people. ncbi.nlm.nih.gov/pmc/articles/P… ImageImage
Add.#17: "A professor at the renowned Johns Hopkins School of Medicine advised Americans recently to "ignore" guidance from the US CDC and Prevention due to the public health agency's puzzling refusal to recognize natural immunity from previous infection."
theblaze.com/news/johns-hop…
Add.#18: "The SARS-CoV-2 Delta variant is poised to acquire complete resistance to wild-type spike vaccines"

Evidence: Vaccines are ineffective with all variants other than the alpha.

(yes the 2020 Spike, LOL @ #BigPharma)
biorxiv.org/content/10.110…

archive.md/rG3Qh ImageImageImageImage
Add.#19:
Add.#20: Gentle Reminder: "Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens"

journals.plos.org/plosbiology/ar…
Add.#21: "Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19"

"[.] determine whether mild infection induces a lasting, multilayered defense."

"recovered [.] had formed an expanded arsenal of [.] specific immune memory cells [.] "

cell.com/cell/fulltext/… Image
ADD.#22: "Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection w/ persisting antibody responses and memory B and T cells"

In a nutshell: Natural immune system doesn't care that much about the Spike, only #BigPharma does. cell.com/cell-reports-m… Image
Add.#23: Gentle Reminder: "Infection-enhancing anti-SARS-CoV-2 antibodies recognize both the original Wuhan/D614G strain and Delta variants. A potential risk for mass vaccination?"

pubmed.ncbi.nlm.nih.gov/34384810/ Image
Add.#24: "Decreased breadth of the antibody response to the S-Protein of SARS-CoV-2 after repeated vaccination"

"[.] These data [.] cast doubts about the convenience of repeatedly immunizing with the same S protein sequence."
medrxiv.org/content/10.110… ImageImageImageImage
Add.#25: "Shedding of Infectious SARS-CoV-2
Despite Vaccination"

"Individuals infected with SARS-CoV-2 despite full vaccination have low Ct values and shed infectious virus."

medrxiv.org/content/10.110… Image
Add.#26: "Epitope-resolved profiling of the SARS-CoV-2 antibody response identifies cross-reactivity w/ endemic human coronaviruses"

This cross-reactivity aquired via natural immunity (adaptive) is now irritated by trillions of transcribed S-subunits.
sciencedirect.com/science/articl… Image
Add.#27: Memetic warfare intermission. Image
Add.#28: "The spike protein of [.] variant A.30 is heavily mutated and evades vaccine-induced antibodies with high efficiency"

🤡: Pouring the same antibiotics ("2020 Spike") onto the antibiotics resistant culture ("A.30")

Antibodies ≠ Immunity

nature.com/articles/s4142… Image
Add.#29: "Vaccine-induced S-specific immunity resulted in severe ALI (acute lung injury) in SARS-CoV infected Chinese macaques."

insight.jci.org/articles/view/… Image
Add.#30: "[.] evidence that antibodies targeting endemic CoV are robustly boosted in response to SARS-CoV-2 infection but not to vaccination w/ stabilized S, [.] the S2 subdomain [.] triggers [.] IgG-dominated response that lacks neutralization activity."

medrxiv.org/content/10.110… Image
Add.#31: "Noooooooo! Singapore! Nooooooooo!"

covid.viz.sg ImageImage
Add.#32: "SARS–CoV–2 Spike Impairs DNA Damage Repair & Inhibits V(D)J Recombination In Vitro

[.] full–length spike protein inhibits DNA damage repair by hindering DNA repair protein recruitment. [.] potential side effect of the full-length spike vaccine."
mdpi.com/1999-4915/13/1… ImageImage
Add.#33: "[.] two different ADE risks have possible implications for SARS-CoV-2 B-cell vaccines [.]. These models place increased emphasis on the importance of developing safe SARS-CoV-2 T cell vaccines that are not dependent upon antibodies."

frontiersin.org/articles/10.33… Image
Add.#34:

ReCap:

•CoronaVirusFetish.exe
•GeneticEngineering.exe
•FurinCleavageSite.exe
•LabLeak.exe
•OriginsLie.exe
•WrongEpitope.exe
•mRNA.exe
•Variants∞.exe
•BigFail.exe

pubmed.ncbi.nlm.nih.gov/32194980/
pubmed.ncbi.nlm.nih.gov/34073934/
pnas.org/content/106/14…
ahajournals.org/doi/10.1161/CI… Image
Add.#35: more salt Image
Add.#36: Image
Add.#37: Flashback 2012: "Immunization with SARS [.] vaccines leads to pulmonary immunopathology on challenge with the SARS virus
[.] vaccines all induced antibody,[.] led to occurrence of Th2-type immunopathology, hypersensitivity to SARS-CoV components."
pubmed.ncbi.nlm.nih.gov/22536382/ ImageImage
Add.#38: Déjà vu 2021:

"Long-lived macrophage reprogramming drives spike protein-mediated inflammasome activation in COVID-19

[.] primary SARS-CoV-2 vaccine antigen (S-protein) [.] drives pro-inflammatory cytokine secretion in human monocytes."

archive.md/l8HcG#selectio… Image
Add.#39: "But muuuuuuh noooo muuuuh"

Flashback: Japan FOIA (@pfizer's own animal testing data)

pmda.go.jp/drugs/2021/P20… ImageImage
Add.#40: "[.] mRNA Vaccine Can Induce Acute Myopericarditis in Mouse Model"

“Aspiration”: pulling back syringe plunger once needle is inserted ⇢ if vein=hit ⇢🩸-signal

"@cdc & @WHO [.] against aspiration [.] to minimize pain."

academic.oup.com/cid/advance-ar…

ibb.co/MDhCKC0
Add.#41: 'Noooo @WSJ Noooooo! Muuuh!'

"Some of the mRNA in the vaccines may also be taken up by heart cells,[.] then produce the spike , [.] lab tests [.] found that heart cells have taken up the @moderna_tx vaccine and then expressed the spike protein."

archive.md/KLKyR
Add.#42:
⇒"muuh mRNA translation in Deltoid only". (No)
⇒♥️-cells producing outdated 2020 Spike=🤡
⇒♥️-cells presenting S-antigen to T-Cells via major histocompatibility complex (MHC)=🤡
⇒♥️-cell tagged 4 destruction
⇒♥️-cells only? (No)

Let that sink in.
Dr. Schneider=noob ImageImage
Add.#43:
⇶: bit.ly/3bXMlov
Misfolding: bit.ly/3n1GIvM
BNT162b2: bit.ly/2YwVlxN
GGT: bit.ly/31Om76e
RNA: bit.ly/3wydVlH
ψ: bit.ly/31TnssB
6XKL: bit.ly/3qnqpf5
Coptigate: bit.ly/2YD7aCQ
Image
Add.#44: "[.] transmission & viral load of SARS-CoV-2 delta [.] in vaccinated & unvaccinated [.] in the UK: fully vaccinated have peak viral load similar to unvaccinated cases.

[.] can transmit infection in household, incl. to fully vaccinated contacts"

thelancet.com/journals/lanin… ImageImage
Add.#45: "First case of postmortem study in a patient vaccinated against SARS-CoV-2

By postmortem molecular mapping, we found viral RNA in nearly all organs examined."

sciencedirect.com/science/articl…

#SafeAndEffective Image
Add.#46: Time for a meme for my NZ bros & sisters to further enjoy the mRNA-Spike-Only-Focus-Circus-Show. Image
Add.#47: Back 2 #NaturalImmunity: fresh:

"Pre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2"

731 healthcare workers, 1st wave: 58 didn't test + despite high-risk. A spike in T-cells.

@jjcouey, in case you missed this.

nature.com/articles/s4158… ImageImage
Add.#48: @Independent not denying #NaturalImmunity anymore.

"Why some people test negative for Covid even though everyone around them is infected"

T cells ‘sniff out’ proteins even when buried within, [.] antibodies ‘grab hold’ of shapes on the surface.”
archive.md/yEF4R Image
Add.#49: Even the @guardian derailing their own Science™ narrative now (also see tweet "Add.#47"):

"The work suggests that a subset of people already had memory T-cells from previous infections [.] common colds, which protected them from Covid-19."

theguardian.com/world/2021/nov…
Add.#50:
@rki_de - responsible for disease control and prevention: 60.9% of symptomatic COVID-19 infections in week 41-44 are assumed to be breakthrough infections

page 22

rki.de/DE/Content/Inf…

Archive: web.archive.org/web/2021111120… Image
Add.#51:
Noo, Fauci, noo!

"According to Fauci, [.] waning immunity VS both infection & hospitalization [.].

more & more of those ppl who are getting breakthrough infections are winding up in the hospital."

"muuh Booster":
Again D614G 2020 S, not Delta.
news.yahoo.com/dr-fauci-just-… ImageImage
Add.#52:
Noooo Billy Boy Noooooo!

@BillGates about his most prized “solution”:

"We didn't have vaccines that block transmission," said Gates, contradicting previous interviews.

"We got vaccines that help you with your health, but they don't reduce the transmission,” he added.
Add.#53:
"[.] boosting with the Beta variant in the preprimed group resulted in better neutralization of the ancestral SARS-CoV-2 strain than the Beta strain. [.] immune imprinting [.] may have occurred."

"Muuuh Boosters work"
Nope ⤑ Immune Imprinting.

cell.com/trends/immunol… Image
Add.#54:

Noooo Taiwan NooooooooOOOoo!
I hate you Taiwan, this will increase mRNA hesitancy. NooooooOOOoo000oo. Muuuuuuuuuh.

"Taiwan suspends 2nd dose Pfizer Covid vaccine for 12-17 olds over heart inflammation"

wionews.com/world/taiwan-s… ImageImage
Add.#55:

Noooo China Noooooo!

"[.] Vaccine Hesitancy Among Medical Students: The Next COVID-19 Challenge in Wuhan, China

The main factors:

⟿ knowledge about COVID-19 vaccine,
⟿ training related to COVID-19 vaccines,
⟿ education level."

pubmed.ncbi.nlm.nih.gov/34496990/ ImageImage
Add.#56:

Nooooo Boston Nooooooo!

Quote:
"Breakthrough cases in Massachusetts have been making up about 35% to 40%.

Breakthrough hospitalizations have been accounting for 30% to 35% [.]."

bostonherald.com/2021/11/16/mas…

Archive:
archive.ph/wip/ORNnM ImageImage
Add.#57:

"'Original antigenic sin' (OAS): A potential threat beyond the development of booster vaccination VS novel SARS-CoV-2 variants

OAS can trigger immune evasion of the emerging variants in those [.] vaccinated VS former versions of the pathogen."

cambridge.org/core/journals/… "Eventually, further w...Image
Add.#58: Now it's time for a political incorrect meme again I found in the chans. I blackfaced the chad to comply to the Twitter-etiquette, I hope that is ok, not? Image
Add.#59: "The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood–brain barrier"

In Vitro, nevertheless, let's keep an eye on that in the next tweets.

sciencedirect.com/science/articl… Image
Add.#60: Evidence for "Add.#59":

"Potential adverse events in Japanese women who received tozinameran (BNT162b2, Pfizer-BioNTech)

[.] cerebral venous sinus thrombosis & intracranial hemorrhage (ICH) associated with BNT162b2, Pfizer-BioNTech, [.]"

joppp.biomedcentral.com/articles/10.11… Image
Add.#60: Evidence for "Add.#59", @AstraZeneca:

"[.] clinicians should be aware that in some patients, venous or arterial thrombosis can develop at unusual sites such as the brain or abdomen, [.] clinically apparent [.] 5 to 20 days after vaccination."

nejm.org/doi/full/10.10… Image
Add.#61: "'Vaccine-Induced Covid-19 Mimicry' Syndrome: Splice reactions within the SARS-CoV-2 Spike open reading frame result in Spike protein variants that may cause thromboembolic events in patients immunized with vector-based vaccines"

researchsquare.com/article/rs-558… ImageImage
Add.#62: Flashback September 2020:

"SARS-CoV-2 binds platelet ACE2 to enhance thrombosis in COVID-19

SARS-CoV-2 virus directly activates platelets and potentiates their prothrombotic function and inflammatory response via Spike/ACE2 interactions."

jhoonline.biomedcentral.com/articles/10.11… Image
Add.#63: FastForward the Sept2020 Flashback in Add.#62 to Mai2021:

"Thrombotic thrombocytopenia associated w/ COVID-19 infection or vaccination: Possible paths to platelet factor 4 autoimmunity

[.] after vaccination with adenoviral vector-based vaccines"
journals.plos.org/plosmedicine/a… ImageImage
Add.#64: Flashback: "SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: Implications for microclot formation in COVID-19

We conclude that the spike protein may have pathological effects directly, without being taken up by cells."
medrxiv.org/content/10.110… Image
Add.#65: "Muuuh S1 only in Deltoid" (Nope)

"[.] (SARS-CoV-2) Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients

[.] detectable levels of S1 antigen in plasma in 11 participants, and spike antigen was detected in 3 of 13 participants."
academic.oup.com/cid/advance-ar… ImageImage
Add.#66: "SARS-CoV-2 Spike Protein Elicits Cell Signaling in Human Host Cells: Implications for Possible Consequences of COVID-19 Vaccines

[.] consider their long-term consequences carefully, [.] when they are administered to [.] healthy individuals [.]."
ncbi.nlm.nih.gov/labs/pmc/artic… Image
Add.#67: "IL-6 Signalling? Nooooo! Muuuuuh!" (Yes)

Flashback December 2020:
"SARS-CoV-2 spike protein promotes IL-6 trans-signaling by activation of angiotensin II receptor signaling in epithelial cells"

pubmed.ncbi.nlm.nih.gov/33284859/ Image
Add.68: "Muuuh IL-6 Signal does nothing Muuuh" (It does)

Flashback 2012: "IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6"

ncbi.nlm.nih.gov/pmc/articles/P… Image
Add.69: More Spike / Cell-Signalling that should be considered:

"SARS-CoV-2 Spike Protein Induces Paracrine Senescence and Leukocyte Adhesion in Endothelial Cells"

journals.asm.org/doi/10.1128/JV… Image
Add.#70: "An evidence that [.] spike damages hematopoietic stem/progenitor cells in the mechanism of pyroptosis in Nlrp3 inflammasome-dependent manner"

Spike itself causes cell damage by eliciting a pro-inflammatory response.

"Muuuh not our Spike" (Sure)
nature.com/articles/s4137… Image
Add.#71: "Muuuuuuh Stop it Bobby Stop it Muuuuuuuuuuh!" (No)
Add.#71: Have a meme to cheer you up, let's return to happier topics, how about Bio Distribution of LNPs?

Image
Add.#72: LNP 101:

⤍LNP could have targeted ligands (outside), would only transfect muscle cells

⤍#BigPharma designed with PEG polymers (outside) to evade immune system

⤍"PEG reason for LNP throughout body, no targeting ligands ⤍ transfect any cell"

cas.org/resource/blog/… Image
Add.#73: "Muuuh Stop it, no more LNP-talk, return to Mutational Dynamics of S1 & Evasion" (OK)

"SARS-CoV-2 immune evasion by B.1.427/B.1.429 variant of concern

B.1.427/B.1.429 S variant [.] unusual neutralization escape strategy."
science.org/doi/full/10.11…
ImageImageImage
Add.#74: "Rates of SARS-CoV-2 transmission & vaccination impact the fate of vaccine-resistant strains

[.] 3 risk factors favour vaccine-resistant strain:
high probability of initial emergence of resistant strain, high Nr. infected, low % vaccination."

nature.com/articles/s4159… ImageImageImage
Add.#75: As "Add.#74" shows: The United Booster Empire will need a lot of micro-management-autism and everything will be tightly scheduled to obtain VIP-status, it's literally a race with time and every day counts. Non-sterilizing mRNA Transfection is no Walk In The Park. Image
Add.#76: "Muuuh Stop the Mutational Dynamics Bobby, stop it now!" (Ok, how about ADE?).

Flashback 2005: "Caution raised over SARS vaccine

[.] a jab against one strain might even aggravate an infection with SARS virus from civets or another species."
nature.com/articles/news0… ImageImage
Add.#77: FastForward July 2020:

"A perspective on potential antibody-dependent enhancement of SARS-CoV-2

hypothesis that ADE is a consequence of low-affinity antibodies that bind to viral entry proteins but have limited or no neutralizing activity."

nature.com/articles/s4158… Image
Add.#78: FastForward September 2020:

"Antibody-dependent enhancement of coronavirus

[.] a potential risk in the vaccine therapy for the novel coronavirus SARS-CoV-2, as it shares the same viral receptor and similar genome sequence with SARS-CoV."

pubmed.ncbi.nlm.nih.gov/32920233/ Image
Add.#79: FastForward Feb2021:

"At the Intersection: SARS-CoV-2 / Macrophages & the Adaptive Immune Response: A Key Role for Antibody Dependent Pathogenesis But Not Enhancement of Infection in COVID-19"

ncbi.nlm.nih.gov/labs/pmc/artic…

ImageImageImageImage
Add.#80:
"Pathogenic priming [.] contributes to serious & critical illness & mortality in COVID-19 via autoimmunity
[.] proteins w/ largest nr. of immunogenic peptides were the Spike & [.] NS3. [.] proteins had at least 1 match to human proteins except 1"
sciencedirect.com/science/articl… ImageImageImageImage
Add.#81:

"Muuuuuh Stop it! Muuuuuh! #SafeAndEffective! 95% Efficiency!"
Add.#82: 95%? Absolute VS Relative Trickery?

Reminder: "COVID-19 vaccine efficacy & effectiveness-the elephant (not) in the room

0·9% for the Pfizer–BioNTech, 1% for the Gamaleya, 1·4% for the Moderna–NIH, 1·8% for the J&J, and 1·9% for the AstraZeneca"
thelancet.com/journals/lanmi… Image
Add.#83: "Noooooo Belgium Noooooo! Muuuuh!"

[via @FatEmperor]
Add.#84:

"Noooooooo Hungary Nooooooo! Muuuuh Nooooo! That's racist! I hate you now! Muuuuh!"

45% of hospitalisations are vaccinated.

hungarytoday.hu/vaccinated-hun…

archive.ph/QfcAk

blikk.hu/aktualis/belfo…

archive.ph/zG6cR ImageImage
Add.#85: Correction for "Add.#79": Wrong manuscript link posted, here is the correct one:

researchgate.net/publication/34…

Add.#86: May I Introduce to you the current political Suicide Commando of Austria: @a_schallenberg, @WolfgangMueckst, @BgmLudwig and many more.

Image
Nooooooo Gibraltar Noooooooo! That's racist! Muuuuuuh! Nooooooooooooooo0000oooo!

"Despite 100 percent vaccination quote: Gibraltar cancels Christmas festivities"

#SafeAndEffective

Illiterate @WolfgangMueckst: "Muuuh our only way out Muuuh!"

…w-berliner--zeitung-de.translate.goog/news/trotz-100… ImageImageImage
Add.#88: "Immunological imprinting: [.] subsequent infections w/ related strains produce a ‘back-boosting’: increased antibody titers toward epitopes shared between current & historic strains encountered earlier in life."

[Thx 2 @Harvard2H 4 pointing out]
nature.com/articles/s4146… Image
Add.#89: further references, analysis and thesis to "Add.#88":
Add.#90: "Transmission potential of vaccinated & unvaccinated persons infected w/ [.] Delta variant in a federal prison, July-Aug21

[.] vaccinated [.] infected no less infectious than unvaccinated [.]"

[thx 2 @fynn_fan 4 pointing out, fan account]

medrxiv.org/content/10.110… ImageImageImageImage
Add.#91: "Noooo Fauci Nooooooo! Muuuh! Noooooooo @NBCNews Noooooooo! I hate you now! No More Interviews Goddamnit!"

nbcnews.com/health/health-…

ImageImageImage
Add.#92: "germany's vakzine fail despite over 67% fully vaxxed covid looks worse than 2020

[.] rotten surprises for those who thought they had vaxxed their way out of this.

this was not a fire extinguisher.

[.], it looks like it was gasoline."

boriquagato.substack.com/p/germanys-vak… Image
Add.#93: I was informed that we are talking mostly about Sinopharm in Hungary, inactivated whole virus immunization w/out mRNA & LNPs: We always knew that only live attenuated approaches are "maybe" the real deal, inactivated exposure + corona viruses⤏🤡

Add.#94: "Nooo BMJ Nooo! Predatory Journal, like MDPI! Muuh"

Peter Doshi (@bmj_latest): "Why would the statistics be so different in the UK? [.] most COVID hospitalizations & deaths are among the fully vaccinated.”

Full:
Add.#95: "Noooooo Muuuuh Peter Doshi is lying! Muuuuh, he is a racist!

Noooo UK Nooooooo Muuuuuuh! Noooooooo! This graph is racist! Muuuuuh! Noooooooooo000ooo!"

archive.md/IvGtq

gov.uk/government/pub…

imgbb.com/w4k4jpt
Add.#96: "Stop it Bobby! Stop it na0!
That's racist! Next Mofo-booster will do the job!" (No)
Add.#97: Did you think this thread is finished? I've to disappoint you, this mRNA-Spike-Only-Focus-Circus-Show is far from finished, most probably this was only the 101-part so far of the Booster-Subscription Service Global PsyOp Saga, a ScriptedReality LARP written by Science™. The Eternal Age of Memetic ...Image
Add.#98: "[.] mRNA COVID Vaccines Dramatically Increase Endothelial Inflammatory Markers & ACS Risk as Measured by the PULS Cardiac Test: a Warning

mRNA vaccine by @moderna_tx & @pfizer [.] changes PULS score [.] from 11% 5 yr [.] to 25% 5 yr ACS risk."
ahajournals.org/doi/10.1161/ci… Image
Add.#99: "Predominance of antibody-resistant SARS-CoV-2 variants in vaccine breakthroughs, San Francisco Bay Area, [.] Fully vaccinated were more likely [.] to be infected by variants carrying mutations associated w/ decreased antibody neutralization [.]"
medrxiv.org/content/10.110… ImageImage
Add.#100: "But muuh above study shows: unvaccinated are more likely to carry 'more infectious' variant"

True, but those are not more lethal (Delta).
Virology101: Always more infectious, less lethal (a.k.a. known as "Endemic"). What if WIV1 variant was already endemic (lab leak)? Image
Add.#101: Reminders:

⤏ Outdated 2020 Spike doesn't do JackShit VS Delta anyway.

"But muuh Booster 3" (Nope, same outdated 2020 Spike still, 1:1 the same as shot 1 & 2, No "Muh"-Delta-Update).

⤏ MutationalDynamics101: Delta Update will be outdated on Release Date anyway.
Add.#102: Add this to the "Add.#101"-equation:
⤏ Immune Imprinting aka OAS?
⤏ Antibody Resistant Variants + SpikeOnlyFocus Directed Evolution = Timebomb?

Geert right? Not sure (nope), he doesn't get Immunology101 right. Underrates natural immunity paths.

Pics: Unrelated memes ImageImageImageImage
Add.#103: I tend to share JJ Couye's view here, still learning Immunology101.

I'll shed some more light on this in a seperate, more holistic thread, outweighing the narrow view of molecular biologists.

What we can say for sure:
mRNA Spike-Only-Focus = Biggest Fail of all times Image
Add.#104: Back 2 Biz:

New UK-Numbers (2 week period till 14/11/21),
Hospitalisations:

⇢Chads: 16.5%
⇢Peasants 1st Dose: 6.8%
⇢Peasants 2nd Dose: 69.6%
⇢Unknown Chad/Peasant-status: 17.0%

bit.ly/3nGOc82
bit.ly/3nFd2Fb

thx 2 @stefan_finding 4 pointing out Image
Add.#105: Referring to "Add.#89":
@Harvard2H had to switch to "private mode", here is his article-link further discussing OAS, implications for the fact that the original Wuhan strain already had a 10 of 10 Spike, adapted to humans.
harvard2thebighouse.substack.com/p/part-ii-unde…
Image
Add.#106: @US_FDA:
⇢21 died vaccinated group
⇢17 died placebo group

"all-cause mortality rate of vaccinated group was higher than that of the control group"⇢6 months
@pfizer trial
bit.ly/3r3SjwQ
https://t.co/M2rVD7O2zP
archive.md/7fLHW
israelnationalnews.com/News/News.aspx…
Add.#107: Noooo Theresa Tam (@CPHO_Canada) Nooooo!

“Delta [.]. It’s..it’s a virus that is very highly transmissible. [.] vaccines are not perfect in terms of reducing infections, [.] vaccinated could get infected [.], uhmm .. similar viral loads to those who are unvaccinated."
Add.#108: Quick Status Quo: Snowflake @trvrb is still hopping around the hot potato, trying to distract away from the whole S1 mutational dynamics problem with massive word salads, a true agenda boy. Had to answer him with my backup account, he blocked me.
Add.#109: I fixed the first graphic in the answer.

Add.#110: @jjcouey debunks snowflake @trvrb (Quote: "The High Priest of Immunomythology with a Blue Check Mark"). Trevor spams with a #DamageControl #BigFail-thread on the question whether mRNA Transfections create more variants: Trevor Failford.

Min. 37: twitch.tv/videos/1215043… ImageImageImageImage
Add.#111: In a nutshell:

⇢"muuh, Codon Optimization is N1-Methylpseudouridine (abbreviated m1Ψ), not Pseudouridine (Ψ) muuh"
⇢in silico analysis: it also alters mRNA secondary structures in vaccines, result: quadruplex formation

osf.io/bcsa6/
ImageImageImage
Add.#112: Time for a meme. Category: When you can't distinguish between meme or truth, IRL meme by the German Government/PR (@die_regierung):
"Statistically, one in 5000 vaccinated people experience a serious side effect such as heart muscle inflammation."
archive.md/JR2kw Image
Add.#113: New Botswana Variant, with many S1 changes are from vaccinated HIV+ patients (B.1.1.5.2.9).

github.com/cov-lineages/p…

nextstrain.org/fetch/genome.u…

All cards are now on the table:
⇢ Vaccinated drive new VOC ?
⇢ Super Endemic ?
⇢ ADE risk ?
⇢ Immune Imprinting ? ImageImageImageImage
Add.#114: Omicron Spike in complex human ACE2:

⇢ This doesn't reveal anything regarding virulence (yet)
⇢ Green ribbon = ACE2, below = RBD (S1 sub unit)
⇢ RBD shows documented phenotypic aminoacid changes, cyan = deletions, green = undocumented

(GISAID screen capture)
Add.#115: "Virological factors [.] increase the transmissibility [.]"

Omicron indicates: might be evolving into irrelevance ("boosters"⇢DoubleLOL)

Virology101:
⇢Deadly⇢shitty transmission
⇢Nothingburger⇢good transmission
pnas.org/content/113/15…

Peasants may face problems ImageImage
Add.#116: Evidence for transfection evasion + maybe endemic patterns

"Muuh Antibodies = Immunity Muuh"
Wrong (Antibodies ≠ Immunity)

Who cares about always-outdated-at-rls-date-Spike-Only primed antibodies? Correct: Peasants.

Booster + Pill anyone 🤡?
bit.ly/3xsXN5F ImageImageImageImage
Add.#117: We're reaching higher memetic dimensions with warp speed now.

"@pfizer pill to be taken alongside vaccines [.]"

WTF I love @AlbertBourla now: PillsBoosterBalls VS #Omicron 4 Peasants. 4D Troll.

archive.fo/UOT0v
archive.ph/Icjo9
"In case our PfizerMec...ImageImageImage
Add.#118:

⇢ConvertReality2Meme.exe

⇢RT News already preparing us for the upcoming dancing season

⇢Belgium declares dancing season constellation - quote: "This is Covid-21"

⇢IRL-MemeticsIntensify.exe

⇢"Do you reme...?"

archive.md/hRgpx
ImageImage
Add.#119: "Muuuh Noooo Bobby Noooo, Stop it, that's racist and tasteless. Muuuh!" (OK Computer, Sorry).

Quick Intermission: Have a relaxing @sesamestreet episode, today feat. ...
Add.#120: "@florian_krammer's pants soaked in ShitNPiss" or "Add.#18 predicted this"

RBD changes:
K417N N440K G446S S477N T478K E484A Q493K G496S Q498R N501Y Y505H

ADE Roulette (Omicron):
⇢K417N🎯
⇢N439K 1 a.a. @ 440
⇢E484K lysine 2 alanine
⇢N501Y🎯
ImageImageImage
Add.#121: Did anyone say #COVID21 ?

@welt predicted this feat. @vonderleyen behind a paywall, @AlbertBourla is lurking there somewhere too for sure, not?

bit.ly/3nYcUkk "Don't forget to downl...ImageImageImage
Add.#122: "Noooo @ProfKlausSchwab Nooooo! Muuuh!"

"@wef cancels meetings over death threats

We couldn't imagine [.] we could end up in the crosshairs [.]"

Who will eat ze bugz now? Who will be happy?

bit.ly/3xwCLD3 "why does klaus schwab...ImageImageImage
Add.#123: "Nooooo @rki_de Noooooo! Muuuh!"

VaxBreakthroughs (V.B.)/Symptomatic:
12-17 years: 6,7%
18-59: 48,8%
60+: 71,4%

V.B./Hospitalisations:
12-17: 7,5%
18-59: 28,2 %
60+: 56,0%

V.B./ICU:
18-59: 15,3%
60+: 46,4%

V.B./Deaths:
18-59: 16,2%
60+: 52,5%
bit.ly/3nWSok7 #SafeAndEffectiveImage
Add.#124:

"Increased risk of infection with SARS-CoV-2 Beta, Gamma, and Delta [.] compared to Alpha variant in vaccinated individuals

[.] after full vaccination, regardless of the vaccine used."

medrxiv.org/content/10.110… Image
Add.#125: "Nooo @TheLancet Nooo! Muuh!"

"Epidemiological relevance of C19-vaccinated [.] is increasing

vaccinated [.] relevant source of transmission

case rate [.] higher among subgroup of the vaccinated compared to unvaccinated in all age groups [.]"

thelancet.com/journals/lanep… ImageImage
Add.#126: "RKI: All confirmed Omikron cases in Germany vaccinated. Those affected showed only mild symptoms, none of them had to go to hospital so far, according to the @rki_de."

archive.ph/YtBH0

More ADE, Original Antigenic Sin, Immune Imprinting Signals. Image
Add.#127:"@US_FDA requested courts to keep this information confidential for no less than 55 years.

Court returned with an order to release 500 documents a month."

We start with the first release of 30+ pages on AE including death."

tl;dr: 1:37 (Fatals)
phmpt.org/wp-content/upl… ImageImageImageImage
Add.#128: Topic: Boosters are shite by @gerdosi.

"[.] adding a 3rd dose of the same vaccine could be counterproductive in the vast majority of recipients, except for the immunocompromised who failed to mount a proper response to the 1st pair of doses."

threadreaderapp.com/thread/1467989…
Add.#129:
Add.#130: Recent Flashback, UK:

"Noooo UK Noooo! Muuuuh!"

"[.] could lead to the production of S protein in unintended places, including the brain, ovaries and spleen [.]"

bit.ly/3pEWooP

archive.md/AqOp4

Athlets-ShitShow Collection:
anotepad.com/notes/swdqxy54
Add.#131: Picturebook ex. why @c_drosten is an illiterate retard:

#Immunomythology High Priest w/ a Blue Check Mark blessed with max ignorance: Original Antigenic Sin, Immune Imprinting, etc. He was/is and always will be a supernoob. Same "Muuuh Sandra".
ImageImage
Add.#132: After so much clusterfck underneath your skull, you deserve a relaxing meme na0, not? Image
Add.#133: Enough jokes, Back 2 Biz:

"By tracking the evolutionary trajectories of vax-resistant mutations in [.] 2.2 million SARS-CoV-2 genomes, [.] occurrence & frequency of vax-resistant mutations correlate strongly w/ the vaccination rates in 🇪🇺 & 🇺🇸."
pubs.acs.org/doi/10.1021/ac… Image
Add.#134: And again we are reaching higher memetic echolons with ultra-warp speed, when reality insta-merges with the Endless-Memes-Potential-Dimension.

Poll below: If you prime your immune response with 2 Alpha Shots + 3 Omicron Shots, what is the result?
Add.#135:
Postdoc Sahin (@BioNTech_Group / @pfizer / @gatesfoundation) announced 3-phases boosters for #Omicron:

What happens if you prime your immune response with 2 Alpha Shots + 3 Omicron Shots?
Add.#136:
Follow-Up Poll:

How many shots & boosters is Sahin here really talking about ?
Add.#137:
Follow-Up XXL Poll:

Of how many shots & boosters is Postdoc Sahin babbling about, goddamnit? (All the answers in Tweet "Add.#136" are wrong. Screw PfizerMectin).
Add.#138: Ok, enough of the circle jerks, maybe all answers are right or wrong in these goddamn polls ("Add.#135"-"Add.#138").

Who cares about whether it's 1,2,3,4,5,6,7/α,β,γ,δ,ο,...💉+ daily PfizerMectin XTC?

Think outside the box.
Time for a Sesame Street-episode to relax. Image
Add.#139: WTF, I love @AlbertBourla now.

@pfizer/@BioNTech_Group Subscription Model 2022 almost complete:

✓Step 1: non-liable contracts
✓Step 2: Hook'Em'Up
✓Step 3: PfizerMectin, 2 pills daily
✓Step 4: "Muuh useless"
✓Step 5: "3x #Omicron-Boosters"

bit.ly/31PBJGk ImageImageImageImage
Add.#140: Goddamn, all my prior tweets concerning the @pfizer/@BioNTech_Group Booster Subscription Model are outdated, they upped the game.

PostDoc Sahin is now talking about a 4th BoosterShot Transfection.

Correctional Poll incoming (next tweet).

www-businessinsider-de.translate.goog/wissenschaft/g… Image
Add.#141: Sahin has upped the game 2day, mentions 4th vax for @pfizer/@BioNTech_Group Booster Subscription (bit.ly/3dHI9tT).

Previous polls=outdated

Correctional Question: How many Shots'N'Boosters are needed to be fully vaccinated in 2022?

#PfizerMectin not included.
Add.#142: Back 2 Biz:
"But muuh Bobby, muuh, it protects a little bit, really, I swear."

Answer: Nope. Official Narrative debunked.
Are we seeing here the core ground truth of non sterilizing transfections in Belgium?

Datasouce:
datastudio.google.com/embed/u/0/repo…

archive.md/1PrSl Image

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More from @Bobby_Network

Bobby Rajesh Malhotra ツ ψ Profile picture
5 Dec
"Muuh Bobby, there's already a draft law in place in 🇦🇹, context: 'mandatory vax' + 'cohersive detention up to 1 year', muuh."

Answer: Nope, Fakenews, it's a repair-draft ordered 1 year ago by the 🇦🇹 constitutional court.
parlament.gv.at/PAKT/VHG/XXVII…
PsyOp101: t.me/bobbynetwork/8… Image
"But muuuh Bobby, even Amnesty International gave a statement"

Answer: Part of the PsyOp, I tend to think the latter. That's how "Open Society" also worked out in Venezuela.

thetimes.co.uk/article/amnest…
"But muuh Bobby, that's racist and antisemitic!"

Nope, it's not, economic hitmen orgas don't care about "skin color", "religion", "ethnics",... they only care about the money flow.

"Muuuh Orange Revolution"
"Muuuh Purple Revolution"
"Muuuh Muuh"

Read 17 tweets
Bobby Rajesh Malhotra ツ ψ Profile picture
29 Nov
Quick #Omicron-getting some facts straight-rundown:

Pushed rumor: "Muuh @WEF mentions B.1.1529 already in July 2021"

Answer: Nope, Disinfo PsyOp by Glowies

No mention of "B.1.1529":
24. July: archive.md/wsJXn
After 26. Nov: archive.md/cSNWn

"WEF stealth editing" "Stealth Editing" by WEF can be interpreted as &qu
"But muuuh Bobby muuuh, even @WHO dates B.1.1529 back to November 2020 (!!! muuuh)."

Nope, screenshot showing "B.1.1529 -> November 2020" is a PS-fakery by Glowies to let you look like an idiot.

archive.md/https://www.wh…

RBD mutations are not possible for the given timeline.
I also checked GISAID: no entries with the naming convention "B.1.1529" can be found there before Nov 2021. BUT: you can find the naming convention "1.1529" in the filename of South American March 2021 Uploads, for whatever reason.
Definitive "B.1.1529" genomes pop up in Nov2021.
Read 20 tweets
Bobby Rajesh Malhotra ツ ψ Profile picture
26 Nov
"Yay Lockdown for the lower caste on the Austrian Titanic"

feat. @WolfgangMueckst (Minister of "Health" ["Security"], @a_schallenberg (unelected Prime Minister), @vanderbellen (Early α-Version Replicant & Bot-President),...

Date: 24th Nov 2021,
General Lockdown Start: 22nd Nov
Minister of "Labour" Martin Kocher (@MagratheanTimes) taking a close-up of Karin Edtstadler's arse (@k_edtstadler, Minister for EU & "Constitution" [sic!], Chancellery 🇦🇹).

Same party, same date, 2 days after General Lockdown Start.

[thx 2 @stefan_finding]

@Kukicat7.
Image
Read 5 tweets
Bobby Rajesh Malhotra ツ ψ Profile picture
24 Nov
@Brucele35110485 @DoHeinerultras Ich hab über diese Problematik noch einmal nachgedacht und auch in der Fachliteratur eine ganze Nacht verbracht. Hier nochmal ein paar Hypothesen, die schlüssig erscheinen: Image
@Brucele35110485 @DoHeinerultras Hypothese 1:

- Körper ist überstrapaziert mit den Milliarden von mRNA Spikes, kann sich in der "Saison" von Influenza, Rhinoviren, etc. nicht mehr auf die Verteidigung derer Konzentrieren, weil alle Immunresourcen damit beschäftigt sind spezialisierte Antikörper zu produzieren.
@Brucele35110485 @DoHeinerultras - In dieser Zeit sollten Immunresourcen frei sein, um adaptive Antikörper zu produzieren (die nicht nur auf das S gehen, sondern auf das M & N Protein aller "Erkältungsviren").

- Und das wäre nur die "Initialantwort", das wichtigste sind immer noch "T-Zellen", nicht Antikörper.
Read 8 tweets
Bobby Rajesh Malhotra ツ ψ Profile picture
23 Oct
What's wrong with your throat & neck @AlbertBourla?


(5:55)
GIFs: bit.ly/3juZ0DG
Read 7 tweets
Bobby Rajesh Malhotra ツ ψ Profile picture
21 Sep
Lo & behold: Our fav trash-modeler with no qualifications in the field, @tomaspueyo, who introduced the 'Hammer and the Dance' LARP to the world, gives us his 'expert'-view on vax politics.

Quote: "[.] long covid [.] can reduce IQ"
archyde.com/tomas-pueyo-th…
@tomaspueyo: “I'm telling you that stories are problem-solving, and I told you 5 minutes ago that they're empathy machines, right? How do you put these two things together? Stories are a way to get into somebody else's brain to see how we solve problems.” ted.com/talks/tomas_pu…
Read 5 tweets

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