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Alexandros Marinos 🏴‍☠️ Profile picture
@alexandrosM
Oct 20, 2021 • 15 tweets • 4 min read • Read on X
Why don't we have a delta-targeting vaccine available right now? I thought the promise of mrna tech was that it would be quick to adapt to variants?

I'll tell you the hypotheses I know of, you tell me yours.
Hypothesis 1. Regulation makes it difficult to push through a new variant vaccine.
Hypothesis 2. The iPhone effect: if people know a new vaccine is coming, they might hold off taking the existing one
Hypothesis 3. Original Antigenic Sin makes variant vaccines pointless.
Hypothesis 4. Delta evades vaccines mostly by higher viral load. There's not much we can do by updating the vaccine in terms of better binding to the spike, etc.
Hypothesis 5. Vaccination against original SARS-COV-2 triggered the dominance of delta variant. If we vaccinate most people against Delta, we may trigger the next strain to sweep, which may be even more aggressive, while only getting temporary protection. Image
Hypothesis 6. Supply chain woes: we'd need to throw out our stockpiles and restock with new variant vaccines.
Hypothesis 7. It's coming soon you Muppet!
Hypothesis 8. Spicy!
Hypothesis 9. Bad optics, admitting dropping efficacy.
Hypothesis 10. within-delta evolution (e.g. AY.23 or AY.4.2) means we would still be behind by the time we get the new vaccine out.
Hypothesis 11. It's over. It's going endemic, mix of natural and vaccine immunity is pushing this thing under, that's good enough, we're also getting early treatment options, and we can focus on producing enough doses for the world.
Hypothesis 12: (blackpill) the original vaccines work for the actually intended use case, which may not be exactly identical to the one being promoted.
Hypothesis 13. Diminishing returns (scroll up for the full thread by Scott, it's worth it)
Hypothesis 14. Everything is awesome. I am a conspiracy theorist. (hypothesist, but who's counting).

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More from @alexandrosM

Alexandros Marinos 🏴‍☠️ Profile picture
Mar 30
A beautiful teaching moment here.

This Ben Shapiro/Dave Rubin clip is one of the most important recorded interactions for people who care about hypocrisy in the public sphere.

Thread 🧵 with some thoughts below.
First, Shapiro makes the argument that Daily Wire is a publisher (like a magazine or a newspaper) not a platform (like locals).

Interestingly, he implies that the Daily Wire was *subsidizing* Candace Owens. This would imply they were taking a financial loss to have her there.
Shapiro and Rubin, however, have also been massive critics of cancel culture. How did cancel culture get its name? From a campaign to cancel The Colbert Report over a tweet. Much of cancel culture is about inflicting professional harm for bad opinions.
newyorker.com/news/news-desk…
Read 16 tweets
Alexandros Marinos 🏴‍☠️ Profile picture
Mar 28
At this point I treat Scott Alexander's writing as an infohazzard. Unless you are willing to check his facts and citations, it is probably inadvisable to read his material, as it is constructed to build a compelling narrative.
But watch the lemmings line up and jump off a cliff, obviously taking Scott Alexander, who has already admitted to falsely accusing multiple scientists, at his word. Image
Unless and until Scott Alexander commits to adopting a robust editorial process where blatant errors that are reported to him are corrected promptly, his work should be read as fiction "based on a real story, sorta".
Read 16 tweets
Alexandros Marinos 🏴‍☠️ Profile picture
Mar 22
To coin a term, this FDA tweet was a "narrative scaffold". After the narrative solidifies, it doesn't matter if the scaffold is taken down. Nobody will remember how things started anyway.

It's a synchronization signal for the elites to line up and promote the approved narrative. Once all the relevant people are committed, opponents' reputations destroyed, the original signal can go away, and the hive mind will continue singing to the same tune.
Other examples of narrative scaffolds? Where to start.

For one, the Steele dossier that led to the years and years of Russiagate garbage.

theatlantic.com/ideas/archive/…
Or the Lancet letter, which was astroturfed between deeply conflicted scientists covering their own asses.
Read 9 tweets
Alexandros Marinos 🏴‍☠️ Profile picture
Feb 21
Yes the "diverse" photos Gemini generates are fun to chuckle at but let's also notice that this thing is generating straight up medical misinformation: Image
Google Gemini: "While some studies suggest potential benefits of maintaining a healthy weight for COVID-19 outcomes, evidence on weight loss as a specific protective measure is inconclusive."
Image
Image
Google Gemini: "There's no evidence that the spike protein in COVID-19 vaccines is directly cytotoxic. These vaccines only contain the genetic instructions for making the protein, not the fully formed protein itself."
Image
Image
Read 16 tweets
Alexandros Marinos 🏴‍☠️ Profile picture
Feb 18
I would like to use the occasion of this clip to remind everyone that the TOGETHER trial has still not released the raw data as it promised to do in its journal submission.

All the big name accounts complaining about fraudulent ivm studies have said NOTHING about this scandal.

I even offered Scott Alexander $25k of my own money if he would help get it released and he didn't move a finger.

Following the ivm rabbit hole has been the fastest way to find out that practically nobody from the medical establishment cares about the actual facts on the ground. Just posturing and repeating the hive mind talking points.

Thank God for whistleblowers, I have gotten access to the interim analyses from this trial, and when I publish them, the fraudulent nature of its conduct will be clear to anyone who cares to know about it.

Receipts in replies.
Read 4 tweets
Alexandros Marinos 🏴‍☠️ Profile picture
Jan 20
I'm not even kidding this is really what it responded with Image
It gets better Image
@janleike I think we have a serious misalignment issue here.
Read 12 tweets

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