11/16/21 morning report learning points!
1) Unexplained ascites can be from multiple intra-abdominal processes. Diagnostic paracentesis is the key first step (get at least 200cc if possible for cytology). Figures from Zach Gray! [1/4]
1) Unexplained ascites can be from multiple intra-abdominal processes. Diagnostic paracentesis is the key first step (get at least 200cc if possible for cytology). Figures from Zach Gray! [1/4]
2) Omental nodularity with ascites on CTAP suggests peritoneal carcinomatosis: but consider mimics such as peritoneal TB, lymphoma, GIST, mesothelioma... and (in California) coccidioidomycosis. [2/4]
pubmed.ncbi.nlm.nih.gov/28203370/
pubmed.ncbi.nlm.nih.gov/28203370/
3) Carcinoma of Unknown Primary can be difficult to tackle. Check out some thoughts from another recent morning report. [3/4]
https://twitter.com/StanfordChiefs/status/1441097156945870862
4) For adenocarcinoma with unknown primary, NCCN guidelines suggest a combination of a platinum agent and a newer cytotoxic agent (taxanes, gemcitabine, irinotecan). Staining patterns for CK7/CK20 may suggest a primary but often more IHC is needed. [4/4]
cell.com/trends/cancer/…
cell.com/trends/cancer/…
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