MIS-C post vax

Most of these cases would be considered:
"C19 hospitalization, unvaccinated"

per CDC definitions of 14 days post 2nd dose is "Vaxxed"

Is priming/immune suppression post dose making kids more susceptible to C19?

Pfizer had 18.2% VE up to 11 days post 1st dose
#1825618
12 yo female
13 days post 2nd dose developed MIS-C
4 Days in Hosp
Not stated whether prev C19 inf
wonder.cdc.gov/controller/sav…

#1822149
16 yo female
9 days post 2nd dose
Active C19 inf - 9 days after 2nd dose of 💉
Diagnosed w/MIS-C
6 days in Hosp
wonder.cdc.gov/controller/sav…
#1813648
12 yo female
26 days post 1st dose
Developed MIS-C in tandem w/C19 inf
5 days in hosp
wonder.cdc.gov/controller/sav…

#1804422
16 yo male
3 days post 2nd dose
C19 infection
Thrombocytopenia
MIS-C susp, but Ecoli found as well
Unknown days in hosp
wonder.cdc.gov/controller/sav…
#1775967
13 yo male
91 days post 2nd dose
Acquired C19 2 months post 2nd dose
Admitted to the hospital for MIS-C 1 month later
5 days in the hosp
wonder.cdc.gov/controller/sav…

#1774987
17 yo male
15 days post 1st dose
Diagnosed with MIS-C
6 days in the hosp
wonder.cdc.gov/controller/sav…
#1774984
16 yo male
12 days post 1st dose
Diagnosed with MIS-C
Obesity
1 day in the hospital
wonder.cdc.gov/controller/sav…

#1745962
12 yo female
1 day post 2nd dose
Recent C19 infection
Diagnosed with MIS-C
11 days in the hospital
wonder.cdc.gov/controller/sav…
#1738602
12 yo male
5 days post 2nd dose
Diagnosed with MIS-C
Tachycardia
Unknown days in hospital
wonder.cdc.gov/controller/sav…

#1722262
15 yo female
12 days post 2nd dose
Active C19 infection
Diagnosed with MIS-C
Pyuria w/o UTI
3 days in hospital
wonder.cdc.gov/controller/sav…
#1713661
12 yo female
13 days post unknown dose
Diagnosed w/atypical MIS-C
Lymphopenia
Multi Organ Involvement
4 days in hosp
wonder.cdc.gov/controller/sav…

#1679319
15 yo male
1 day post 2nd dose
Admit to hosp 8 days post vax
Diagnosed w/MIS-C
4 days in hosp
wonder.cdc.gov/controller/sav…
#1666134
17 yo male
27 days 2nd dose
Admitted to the hospital after 4 days of symptoms
Diagnosed with MIS-C
Ocular Hyperamia
Unknown Days in Hosp
wonder.cdc.gov/controller/sav…

There are around 15 more. There are MIS-As as well. This is a sampling.

Is the 💉 protecting from MIS-C?

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More from @JeanRees10

18 Nov
Still haven't heard back from the @US_FDA on the mathematical errors in the Comirnaty BLA docs

The difference of 154 cases, (8 vax, 162 placebo) from which the VE was based on, could be completely wrong, based on this error

Putting the whole world wide roll out into question ImageImage
When adding 2,285 + 2,636 that = 4,921

Also, when subtracting the neg results, that would leave:
Vax 2,285 - 2,026 = 259 -- Which is dif than the 303 referred to later
Placebo 2,636 - 2,305 = 331 -- Which is dif than the 396 referred to later

Total then would be 590 vs. 699 Image
When adding the reasons:
Swab was not taken = Vax 210, Placebo 267 = 477
Swab was taken outside symptom window = Vax 80, Placebo 88 = 168
Swab was taken but results not available - Vax 13, Placebo 41 = 54

Total Vax 303, Placebo 396 = 699
Read 5 tweets
16 Nov
Highly recommend @GirardotMarc 's articles. He makes complex immunological processes understandable.

It should be noted in the FDA EUAs & at the 9/17/21 VRBPAC, Pfizer's Jansen could not establish a "correlate of protection" to Abs

At the 5:37 mark


🧵 Image
The case being made for boosters is based on waning antibodies. Something that vaccine manufacturers can't establish if there is a "correlate of protection" to.
Pfizer's Jansen quote:

“We actually looked at our breakthrough cases in our placebo-controlled phase 3 study, and have compared the antibody titers where we had the opportunity in individuals that got the disease versus the ones that didn’t,
Read 5 tweets
15 Nov
Pfizer 5-11 yo trial contained the buffer PBS

FDA allowed Pfizer to change the buffer to Tris for the public 5-11 yos. Never trialed

Now, let me take you on a thread where this gets super interesting, esp, in light of the administration errors, that @BearGauss highlighted

1/6
Here are the slides from the 10/26/21 VRBPAC where they say they used PBS for the Trial, but that the orange cap formulation coming out for 5-11 yos will contain Tris.

Tris is not in the 12+ Pfizer vaccines that has been deployed in the purple cap, PBS is.

2/6 ImageImage
In the FDA updated BLA/EUA they make a special point to say that PBS is not approved for 5-11 yos, only Tris is. So they trialed 5-11 yos with PBS, are sending untrialed Tris to the public 5-11 yos.

3/6 Image
Read 6 tweets
14 Nov
FDA said "NO!" on 8/22/21
BLA issued on 8/23/21

"We also call on FDA to require a more thorough assessment of spike proteins produced in-situ by the body following vaccination—including studies on their full biodistribution, pharmacokinetics, & tissue-specific toxicities."

1/2
"We ask the FDA to demand manufacturers complete proper biodistribution studies that would be expected of any new drug and request additional studies to better understand the implications of mRNA translation in distant tissues"

2/2

bmj.com/content/371/bm…
Do the FDA Regulators seem like serious scientists?

They don't ask questions on a novel "vaccine" that has never made it to market.

They don't know how/what/why/how much spike is generated, and aren't interested in knowing. Why?
Read 4 tweets
13 Nov
Coming back to this, thinking about the primary clinical endpoint of the vax, "reduce symptomatic infection".

That Pfizer's Kathrin Jansen at the VRBPAC meeting could not establish "correlates of protection" to Abs. Yet, the FDA allowed children's vaxxes to be EUA'd off of them
At the ~5:37 mark:


“We actually looked at our breakthrough cases in our placebo-controlled phase 3 study, and have compared the antibody titers where we had the opportunity in individuals that got the disease versus the ones that didn’t, (con'd)
and we were also unable to really come up with an antibody threshold. So I think there’s probably a much more complex story and not easily just addressed with neutralizing antibodies.”
Read 4 tweets
13 Nov
Dr. Peter's Doshi (Univ of MA, and editor at BMJ) @ 11/2/21 Roundtable - 💉 injuries and mandates

?ing what:
"EVERYBODY KNOWS"

Asking if we really know that from what was demonstrated in the clinical trials or if that is what is what PHOs purported

faculty.rx.umaryland.edu/pdoshi/files/2…

🧵
"Or why would the statistics be so different in the UK, where most covid hospitalizations and deaths are among the fully vaccinated? There’s a disconnect there -there’s something to be curious about - there’s something not adding up (con'd)"
and we should all be asking “is it true that this is a pandemic of the unvaccinated? What does that even
mean?”
Read 9 tweets

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