👋Hi Journalists! Are you interested in covering the new B.1.1.529 #B11529 variant🦠? Here's a link to a TABLE with the names & institutions of THE PEOPLE WHO DISCOVERED THIS VARIANT & SHARED THEIR DATA via the @GISAID community.
PLEASE REACH OUT! 🙏 dropbox.com/s/vb6k9l6ekl24…
In Botswana you have, for example the source of
@GISAID Accession ID: EPI_ISL_6752027, virus sample collected Nov 21, 2021, these authors from the Botswana @Harvard HIV reference laboratory...
Let me tell you their names, Sikhulile Moyo, Wonderful T. Choga, Dorcas Maruapula, Keoratile Ntshambiwa, Sefetogi Ramaologa, Thongbotho Mphoyakgosi, Boitumelo Zuze, Botshelo Radibe, Legodile Kooepile, Ontlametse T. Bareng, Pamela Smith-Lawrence, Kgomotso Moruisi, Roger Shapiro
..Shahin Lockman, Joseph Makhema, Mphaphi B. Mbulawa, Mosepele Mosepele, Simani Gaseitsiwe. Let's please thank them for their important work!
In South Africa, working with @Tuliodna, we have many authors to thank too. For example GISAID Accession # EPI_ISL_6699739 was submitted by Dr. de Olivera with these authors:Kathleen Subramoney, Florette Treurnicht, Avani Bharuthram, Nkhensani Mtileni, NGS-SA...
NGS-SA (Scheepers C, Hsiao M, von Gottberg A, Bhiman J, Lessells R, Bester P, Engelbrecht S, Preiser W, Mdlalose N, Mlisana K, Goedhals D, Everatt J, Amoaka D, Makatini Z, Hardie D, Maponga T, Iranzadeh A, Williamson C, Venter M, Oluwakemi M, Nyaga M) Giandhari J, Pillay S, ...
Naidoo Y, Ramphal U, Ramphal Y, Arisha Maharaj, Moir M, San JE, Tshiabuila D, Tegally H, Wilkinson E, de Oliveira T
In Hong Kong we have to thank, for example for: Accession: EPI_ISL_6590782,
Virus name: hCoV-19/Hong Kong/VM21044713-1/2021
Collected Nov 13, 2021, the following authors: Alan K.L. Tsang, Peter C.W. Yip, Ken H.L. Ng, Edman T.K. Lam, Rickjason C.W. Chan.

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More from @macroliter

25 Nov
JOURNALISTS … please! Scientists in Africa absolutely did share these viral genome 🧬 data as part of the GISAID community. That’s how @PeacockFlu was able to see it. Their work is how these variants are known at all. These scientists have names, too. 😠 newsweek.com/b-1-1-529-new-…
FOR EXAMPLE… here’s a thread 🧵 from one of the scientists in Africa who has helped lead this very important work.
Read 8 tweets
23 Nov
Speaking out that “COVID is airborne” was helpful and important. But muckraking on COVID-19’s origins is a bit tawdry, TBH. 🧵
I abhor gatekeeping but there are actual experts and it’s worth listening to them.
Where did COVID-19 come from? If you look at the most careful analyses, the wet market is screaming hot & underscores a very high likelihood of natural emergence.
Read 5 tweets
14 Oct
Some very good "let's-not-make-a-scariant" coverage from @NOLAnews..it was a pleasure to talk to @emily_woodruff_ about the B.1.630 variant.. Also.. it's important to note that I'm speaking of "Collection Dates" NOT "Submission Dates". Backstory 🧵:
Why was this news? Our team recently sequenced some Aug 2021 samples from the Baton Rouge clinic & found 2 that were B.1.630. B.1.630 is a noteworthy variant 👀 with a freaky number of convergent Spike mutations shared by "Variants of Concern".. BUT... outbreak.info/situation-repo…
Even tho B.1.630 shares L452R with Delta, D950N with both Mu & Delta..and its T478K is almost like Delta's T478R, and it has H655Y like Gamma, & its E484Q is analogous to E484K found in many VOC/VOI, .......B.1.630 just can't complete with Delta.
Read 11 tweets
2 Oct
Hey, y'all.. I deleted my earlier tweet relaying a concern that #Molupiravir might also mutagenize our own DNA. Why did I delete it? Because I was wrong. An expert who I absolutely trust DM'd me to say the following: 🧵 (TL;DR: my concern is unfounded)
"People don’t realize how much sequencing & safety studies have been done just to get to this point. And it is far far less mutagenic (if at all) than the deoxy nucleotide analogs that have been used long-term for HIV patients for decades!"
My colleague added: "Molnupiravir is only used temporarily and has a short window of therapeutic efficacy (as for any respiratory pathogen drug). This will be more life saving for flu treatment than oseltamivir when it gets finally approved for flu." #AntiviralsWork
Read 4 tweets
30 Sep
The only problem is there isn’t just one route to disease susceptibility. There are lots of things that matter besides your “general health” (1) dose of virus you’re exposed to (2) genotype .. eg can you express prenylated OAS1, (3) do you have interferon auto-antibodies? 🧵
And… Not all humans can express the membrane anchored version of the viral “sensor” OAS1
Read 4 tweets
30 Sep
One of my favorite —but sadly, quite common —misconceptions is that people who eat a healthy diet & exercise a lot are naturally resistant to influenza & coronaviruses…
NO YOUR VITAMIN D, CROSS FIT ROUTINE, & FRESH GOJI BERRY SMOOTHIES WON’T HELP YOU… the virus likes to replicate in well fed cells. 🦠 😋
Even though immune suppression, high blood pressure, and chronic disease in general does predispose to worse outcomes, a virulent virus by definition can make a healthy person sick or even kill them.
Read 7 tweets

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