🧵 1/ We MUST start a conversation about "data bros / broettes."
These are people who subscribe to a kind of idiot-version of Humean empiricism. They have zero grasp of deduction/abduction, and they genuinely believe it is impossible to predict real outcomes without "The Data."
2/ For those don't know, here's a quick summary of deduction, induction, and abduction before we get into the weeds.
It's important to understand HOW we generally think and reason before we discuss WHAT we think and reason. merriam-webster.com/words-at-play/…
3/ Next, here's a great overview of Hume (who was a genius), if you don't know what I mean by "idiot-version of Humean empiricism": plato.stanford.edu/entries/induct…
4/ Empiricism, and indeed ANY inductive framework, is a great way to test and confirm science.
BUT it's a horrible way to anticipate future outcomes for which there is *obviously* no data yet (it cannot sufficiently save lives from NOVEL threats...).
6/ One concept that's been discussed among Covid interlocutors as an antidote or alternative to our overly-inductive scientific paradigms is the "Precautionary Principle": en.wikipedia.org/wiki/Precautio…
7/ Importantly, medicine is not the only science (or science-based) field that is suffering from this rise of hyper-induction. The phenomenon is EVERYWHERE.
The video below mocks it rather well, but unfortunately its implications are no laughing matter:
8/ In fact, I posit a rather controversial thesis below.
I believe those who are intellectually courageous and who are willing to consider *fully* the causes of our ever-rising Covid body count will ultimately arrive at the same conclusion:
"There's still no evidence that the aliens mean us harm. Everyone saying otherwise is just fear-mongering."
10/ Data Bros: "Okay, look. There was NO way to know that the aliens were going to blow up the Empire State Building. Now that we DO have the data, it's only a sample size of n=1! There's NO evidence yet that the aliens are going to engage in regular destruction. Keep calm."
11/Data Bros: "Still only n=2!!! If you're risk-averse, you can start taking reasonable precautions, but look...it takes time for data and science to come in. And, from a public policy standpoint, panicking when there's SO LITTLE DATA is neither scientific nor prudent!"
12/ Seriously though: how can we fix this ossified data-bro paradigm crippling the human species' ability to think and neutralize novel threats?
In the short-term, let's use our deductive/abductive capabilities. Let's REASON from known mechanisms:
Here's their TL;dr premise: Viruses that are "pre-adapted" to human ACE2 receptors would by definition stop mutating.
You don't need a virology background to know how silly this is from an evolutionary standpoint.
E.g.
"If SARS-CoV-2 resulted from attempts to adapt a SARSr-CoV for study in animal models, it would likely have acquired mutations like N501Y for efficient replication in that model"
LOL. Why would it "likely" have acquired these? They don't say.
"Recurring mutations...including N501Y...E484K/Q... similarly enhance viral infectivity and ACE2 binding, refuting claims that the SARS-CoV-2...was optimized for binding to human ACE2 upon...emergence"
Literal nonsense unless your premise is that viruses stop mutating.
Denying lab leak outright, however, WAS an actual conspiracy.
The next day after you looped Andersen in this🧵to help dunk on Cotton's comments, he wrote to Fauci: "genome [was] inconsistent with expectations from evolutionary theory."
1/15🧵A major obstacle to fixing our #LowIQPandemic is "à la carte reality" (ALCR), which is information silo-ization hardened by scaled confirmation bias.
The democratization of information has obvious & great benefits. BUT it's enabled ALCR.
A quick example=Covid "knowledge."
2/ Covid has been such a clusterfuck that I hesitate to analyze how we ended up here in a quick 🧵.
But no matter the diagnosis, we can agree on the result: most ppl have preferred sources for Covid info/narratives.
Now—having preferred sources is NOT *ipso facto* a problem.
3/ But it IS a problem if 99+% of ALL info sources are *fatally* wrong.
Here's a Dunning-Kruger (DK) metaphor.
Those in the top %tile of Covid knowledge—on the "Plateau of Sustainability" like @R_H_Ebright—can see reality but have no way of enlightening (at scale) those below.
Our NIH—& DOD—allowed *and* funded this guy to work with the WIV, find the worst coronaviruses on earth, then genetically modify them to be MORE infective to human tissue.
And now he’s on the WHO committee investigating...himself.