Tweet

vasan

22 Dec, 4 tweets, 1 min read

https://twitter.com/rnaianalyst/status/1473769164275949569

#Novavax 3rd dose increased Omicron specific Anti-spike IgG to a jaw dropping 73.5 % !!! It blows every other platform out of the water. $NVAX

https://twitter.com/rnaianalyst/status/1473769164275949569

Correction - 73.5 fold not percent.

The 73.5-fold increase was higher than for Pfizer and Moderna booster shots, which increased antibody levels 25-fold and 37-fold, respectively.

• • •

Missing some Tweet in this thread? You can try to force a refresh

This Thread may be Removed Anytime!

Twitter may remove this content at anytime! Save it as PDF for later use!

More from @doctorvasan

vasan

@doctorvasan

24 Dec

Scientific Basis for #Novavax #Covovax NVX-CoV2373 Superior Efficacy against broad range of Variants
Unlike the mRNA and adenovirus vaccines which only present a portion of the spike protein RBD (Receptor Binding Domain) to the immune system, Nuvaxovid presents the entire 1/9

https://twitter.com/wanderer_jasnah/status/1473409777300557834?s=20

“prefusion stabilized” Recombinant spike protein in a virus-like particle. The remainder of the spike protein apart from RBD’s in Nuvaxovid is also a site of neutralizing epitopes and that region is not heavily mutated in omicron.

https://twitter.com/wanderer_jasnah/status/1473409777300557834?s=20

NVAX (academic 2/9

collaborators actually) used a wild-type virus assay which means they used actual prototype and omicron viruses in the assays. They tested against the real deal. Moderna OTOH measured neutralization in a more common pseudo-virus assay – a non-coronavirus engineered to have 3/9

Read 11 tweets

Share this page!

vasan

Try unrolling a thread yourself!

More from @doctorvasan

vasan

Did Thread Reader help you today?

Like this author's thread?