André Martin Mansoor Profile picture
Dec 31, 2021 9 tweets 3 min read Read on X
1/9
You hear an extra transient heart sound near S1. Now what?

(All sounds in this thread best heard with headphones/good speakers)
2/9
Not sure you hear three sounds? Here is normal S1 and S2 to serve as a control. There are two sounds. Listen to this clip and then re-listen to the above clip. When you do, you will hear three sounds. Two near where S1 should be, followed by S2.
3/9
So what's the differential for extra transient sounds near S1?

DDx:
Split S1
S4 gallop
Ejection click
4/9
Split S1 and S4 gallop can be challenging to distinguish because both are best heard over the APEX area. However, the split S1 sounds are closer together than the S1-S4 interval. And the S4 is best heard with the BELL of the scope. Listen to this split S1:
5/9
Now take a listen to this S4 gallop:

Notice that the S1-S4 interval is longer compared to the split S1 above. And while we are listening over the same area of the chest (apex), the bell is being used rather than the diaphragm.
6/9
What about the ejection click? It is perhaps the easiest to distinguish because it is best heard over the BASE of the heart - very atypical for the split S1 and S4. The click is best appreciated with the diaphragm of the scope as it is higher pitched.
7/9
So back to our patient. What is the extra sound?

It is heard over the base of the heart with the diaphragm. This is an ejection click.

(It was picked up on routine exam and led to the diagnosis of a severely dilated aortic root. Surgery is in 3 weeks.)
8/9
Remember that the exam is never performed in a vacuum. You will also have the benefit of the history and other findings. Does the patient have longstanding HTN (S4)? Does the patient have a giant a wave with an RV heave suggestive of pulmonary hypertension (click)?
9/9
Thanks for reading. For more, pdxpdx.com.

Earlier this week we covered extra transient sounds near S2. Would you like a thread on systolic murmurs next?

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More from @AndreMansoor

Jun 22
1/11
Una joven ingresa con epiglotitis aguda (bacteriemia por H. influenzae). Durante su hospitalización, la paciente desarrolla pancreatitis aguda y hematuria con IRA.

Un conjunto de problemas bastante confuso ¿Cómo podemos encajar todas las piezas de este rompecabezas? Image
2/11
En un paciente con hematuria, la primera pregunta que siempre hago es: ¿cuál es el origen de la sangre? ¿glomerular o no glomerular? Image
3/11
¿Cómo saber si la hemorragia es de origen glomerular o no?

Tenemos que evaluar el sedimento urinario, pero los ojos no pueden ver lo que la mente no sabe. Entonces, ¿qué estamos buscando? Image
Image
Read 11 tweets
Jun 17
1/11
A young woman is admitted with acute epiglottitis (w H flu bacteremia). While hospitalized she develops acute pancreatitis and hematuria with AKI.

A confusing constellation of problems. How can we glue this story together? Image
2/11
In a patient with hematuria, the first question I always ask is as follows: what is the source of that blood? Is it glomerular or non-glomerular? Image
3/11
How can we tell if the bleeding is glomerular or not? We have to evaluate the urine sediment. But the eyes can't see what the mind doesn't know. So what are we looking for? Image
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Read 11 tweets
Jun 4
1/10
A 70-year-old man presents with dyspnea. What do you notice when you first meet him?

This finding should generate a hypothesis, which we will circle back to eventually. Image
2/10
Before we do, let’s talk about dyspnea. The two main systems responsible for dyspnea are the heart and lungs. Image
3/10
The jugular venous pulse can serve as a pivot point. It can take you toward or away from the heart. With this in mind, let’s evaluate the patient’s neck. Here, he is in the upright position. (Sometimes the jugular venous pulse is better seen on the left.)
Read 10 tweets
May 14
1/16
A 30 year old man presents with tea-colored urine. Image
2/16
Our instinct is to consult the framework for hematuria: Image
3/16
Then we realize that while the color of the urine could absolutely be consistent with hematuria, there are mimics of hematuria that should be considered as well. Image
Read 15 tweets
Apr 21
1/13
A man is admitted with acute abdominal pain, nausea, vomiting, and diarrhea. HR 130, BP 90/52.

You walk into the room to meet the patient. What do you notice? This should generate at least one hypothesis. Image
2/13
You ask him for an old photo for comparison. His wife pulls out her phone and produces this picture (B) taken about 10 years prior.

Pt reports darkening of skin over an 8 year period (for which he saw several clinicians). What conditions are you considering? Image
3/13
Let’s first consider the hypotension. Image
Read 13 tweets
Apr 9
1/
A middle-aged man presents with acute sudden-onset dyspnea and hypotension. He is sitting upright.

What do you notice? Let’s see if we can figure out the cause of hypotension.
2/
First.

What are the 4 basic mechanisms of hypotension?

Hypotension can be hypovolemic, cardiogenic, distributive, or obstructive. Image
3/
Hypovolemic hypotension occurs because of a decrease in preload. The pump is ready, the blood vessels are ready, but the "ammunition" is not there. JVP low, extremities cool.

2 arrows down for CVP/JVP since that is the primary issue. Image
Image
Read 20 tweets

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