While working on a cure for his son's chronic fatigue syndrome, has Ron Davis laid the groundwork for understanding long Covid? 👇 thetimes.co.uk/article/could-…
ME/CFS - or chronic fatigue syndrome - is thought to affect 20 million people worldwide, including the mounting numbers of people suffering from long Covid
Symptoms of ME/CFS include:
🔶 Bone-deep fatigue, often accompanied by chills
🔶 Muscle pain
🔶 Cognitive confusion known as “brain fog”
🔶 Sensory sensitivities
Although it’s now widely accepted to be a physical illness, many doctors remain ignorant or dismissive of ME/CFS today, and there is an enduring view that sufferers are just lazy or that they should be able to do something about it themselves
Whitney Dafoe went from a lively, travel-mad twentysomething to being bedbound with ME/CFS, leaving his father - Stanford biochemist Ron Davis - determined to find a cure
Following bouts of illness in his teens, Dafoe became bedbound at 29, unable to move, eat or speak.
His parents worked day and night, changing his urinal and IV drip, attaching bags of liquid nutrients to his feeding tube and putting ice on the tender part of his stomach
Davis set up the Stanford ME/CFS Collaborative Research Center and enlisted the help of esteemed researchers.
In 2015 he helped to publish a report for the US Institute of Medicine that concluded that this was indeed a biological disease, not a psychological one
“Doctors just didn’t know what to do with him,” Davis says. “Blood tests, everything like that came back normal. I decided I’d have to work on it myself.”
He began analysing his son’s blood in his lab, looking for what had gone wrong in the cells’ molecular pathways
That year, Davis had a breakthrough. Poring over his son’s charts he realised there was something wrong with Dafoe’s ability to generate the essential energy molecule ATP - irrefutable proof that something was happening at a cellular level
Now 38, Dafoe has been through some very dark periods but there is hope. Various drugs helped him to recover the strength to sit up and he learnt to communicate via gestures
“Hope is a choice I have made,” says Dafoe. “I decided at one point that I simply was never going to give up. I just have a gut feeling that I will get better, that my father will find a cure and I will fully recover”
In doing so, Ron Davis just might help millions of sufferers of long Covid too.
Gyms are exercise call centres: soulless, atomised and sad. Peloton bikes are all the hard bits of cycling — toil, pain, sweat — without the fun of whizzing through a landscape or getting somewhere
It was boot camp Janice Turner missed most in lockdown (Zoom classes indoors were no substitute)
In early 1999 Prince Andrew went on holiday. His friend Ghislaine Maxwell had introduced him to her boyfriend, the billionaire American businessman Jeffrey Epstein thetimes.co.uk/article/how-pr…
Flight logs later showed that in February that year the Duke of York flew on Epstein’s private jet to the US Virgin Islands, where Epstein owned an island thetimes.co.uk/article/ghisla…
In January 2001 the prince welcomed the new year surrounded by topless women aboard Epstein’s yacht in Thailand thetimes.co.uk/article/andrew…
Australia has revoked Novak Djokovic’s visa for a second time but has agreed to delay his deportation thetimes.co.uk/article/austra…
Nick Wood, the star’s lawyer, also appealed for him to be allowed to stay out of immigration detention as the case proceeds. He said that “time was precious”, given that the Australian Open starts on Monday thetimes.co.uk/article/austra…
If unsuccessful, Djokovic faces being deported and, potentially, banned from the country for three years thetimes.co.uk/article/novak-…
It is understood that the duke will also no longer be styled “His Royal Highness”
“The Duke of York will continue not to undertake any public duties and is defending this case as a private citizen”
Earlier today former members of Royal Navy, RAF and Army described in an open letter to the Queen their “upset and anger” at Andrew retaining the titles saying that his position was “untenable” and urging her: “Please do not leave it any longer.”
The prime minister’s principal private secretary, Martin Reynolds, is said to have begun to regret sending the garden party email shortly after he sent it
“After what has been an incredibly busy period we thought it would be nice to make the most of the lovely weather and have some socially distanced drinks in the No 10 garden this evening”
At the time, England was in a full lockdown, with people barred from leaving their homes unless there was a “reasonable excuse.”
“When that email from Martin dropped we were all messaging each other saying ‘What the hell is Martin thinking?’,” a government source said
A campaign for banning strip clubs in Bristol has been backed by the city’s mayor Marvin Rees. Strippers warn that such a ban will push the sex industry underground and put them in “more danger” thetimes.co.uk/article/bristo…
🗣️ “If the clubs were to close down there is a very strong possibility that the industry would go underground, it would go in hotels or Airbnbs, where there are basically no workers’ rights”
“Violence against women and girls is a significant issue,” Mark Shelford, Avon and Somerset’s police and crime commissioner says. “Specifically objectifying women, misogyny, is of great concern and sexual entertainment places are very much a part of that”