1/ Tweets comparing the #corsironsenthalbox and portable HEPA filtration, including my own. I want to be clear that this is NOT a competition. The whole idea behind a CR box was to provide a viable and effective option for those without the resources to purchase a HEPA system.
2/ In fact, both will absolutely lower respiratory aerosol particles that convey the Omicron variant or other infectious agents. Both will reduce your inhalation dose to these agents, and that reduces your probability of infection and possible adverse outcomes.
3/ The CR box has the advantage of being much less expensive and highly effective if constructed well, and also a cool project and learning exercise for many. It has the disadvantage of being homemade (quality of construction varies) w/ possible leakage if kicked, etc.
4/ HEPA filtration systems have the advantage of not being homemade, and thus consistent engineering quality without much chance of filter by-pass or leaks if someone kicks it, etc.
5/ Neither is right or wrong. They can both work very well. I have two very good HEPA air cleaners in my home & purchased 60 of them for my college (used in shared spaces, conference rooms, etc.). We are now adding 50 CR boxes. Why? because both work to lower risk of infection.
6/ The bottom line is that COVID-19 is an airborne infectious disease. Vaccines are a gift and we should all be thankful for the opportunity to become vaccinated. But we should also strive to dramatically lower our inhalation dose of virus-laden respiratory aerosol particles.
7/ We have the tools to do that. High quality masks, increased ventilation, improved filtration in HVAC systems, and good portable HEPA filtration systems or #corsirosenthalbox es. No rocket science, folks. Just do it, so we all see better days much sooner.

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More from @CorsIAQ

12 Jan
1/ In case anyone wants to see data that show how effective the #corsirosenthalbox is for a home office and a classroom at roughly 1/4 the price of HEPA #1 (which is a good system). Submitted (in peer-review) paper by Team @CappaSnappa @UCDavisCOE.

medrxiv.org/content/10.110…
2/ By application of results, range of equivalent ACH in a typical 2-person dorm room = 20 to 27 (low to high setting). For comparison, hospital isolation rooms typically designed for > 12 ACH.

Range for a 700 ft2 classroom w/ 9 ft ceiling = 5.7 to 7.6 ACH (low to high setting).
3/ Don't let anyone tell you that we cannot DRAMATICALLY lower inhalation dose of virus-laden aerosol particles w/o huge cost, particularly in spaces w/o elevated ventilation or non-universal high quality mask usage. No rocket science, folks. Just do it!
Read 4 tweets
8 Jan
1/ Since start of the pandemic there's been one obvious and absolute truth. COVID-19 is an airborne infectious disease. As such, to reduce chance of infection and community spread we must significantly reduce the amount of virus-laden aerosol particles that we inhale. Period.
2/ That was true every second of every day before vaccinations, and while vaccinations are critical for reducing severe outcomes of infection, we should still be doing everything possible to reduce our inhalation dose of virus-laden aerosol particles. The steps are simple, folks.
3/ Wear a high-quality mask (e.g., KN95 or N95) at all times while indoors w/ others outside your own family.

Avoid indoor spaces where people are not wearing high-quality masks or masks at all.

Where one has control, ventilate to a much greater degree.
Read 6 tweets
5 Jan
1/ Reducing respiratory aerosol particle concentrations in dorm rooms.

I have heard from parents who have children returning to dorms at universities across North America. The #corsirosenthalbox can help with these situations a lot! Really a lot, folks. read on.
2/ 8 hours unmasked while sleeping each night w/ 2 or 3/room should be a concern regarding infection, not to mention being poorly-masked while studying with others in the room.
3/ Increasing ventilation will help to reduce respiratory aerosol particle concentrations to the extent it is possible, but will be limited by system constraints or inoperable windows.
Read 8 tweets
1 Jan
1/ Some thoughts spurred by the guidance below

6 eACH (ventilation + filtration) is somewhat arbitrary, but a reasonable guidepost. Keywords here are "at least." The allusion to 95% removal of contaminant in 30 min is a bit deceiving. It ONLY relates to after source is removed. Image
2/ For a well-mixed indoor air space, an increase in eACH from, say, 2/hr (unfortunately not untypical for K-12 classrooms) to 6/hr yields a maximum decrease in indoor aerosol concentration of 67% and not 95%. Starting at 3/hr = max of 50% reduction w/ increase to 6 eACH.
3/ And the net benefit is particle size dependent, as particle deposition to surfaces is a third sink (removal mechanism) that adds to removal by ventilation and filtration.
Read 18 tweets
31 Dec 21
1/ The governor's words might be turned on those making such absurd statements. Inhalation of aerosols that contain the SARS-CoV-2 virus causes COVID-19. Right-sized HEPA air cleaners can be effective at reducing aerosol concentrations in classrooms.
2/ It is one important intervention amongst others (vaccines, masks, ventilation, testing) & plays a magnified role when significant increases in ventilation are not possible, when children have masks off, and/or some are not vaccinated. But it provides benefit in all scenarios.
3/ There have been dozens and dozens of peer-reviewed papers in high quality journals by high quality researchers that reinforce the value of HEPA filters for lowering indoor aerosol levels, even during the past two years and in the context of COVID-19.
Read 7 tweets
23 Nov 21
1/ With COVID-19 on the rise (again). Remember, the SARS-CoV-2 virus is transported by respiratory aerosols. INHALATION of aerosols is the dominant transmission pathway. Many of us have not wavered on this fact since early in the pandemic. It's about inhalation dose, folks.
2/ Since the dominant pathway is INHALATION of virus-laden respiratory aerosols, then reducing inhalation dose of these particles or inactivating viruses in the particles is the answer to reducing infection (pre- or unvaccinated & even vaccinated breakthroughs).
3/ Science & engineering gave us all of the tools we need to drive this pandemic into the ground. Vaccinations are a gift handed to us on a silver platter. The rest is not rocket science. The rest should be common sense.
Read 7 tweets

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