1. Recent cohort study which is the first to investigate the long-term natural history of GTPS over 11yrs & whether there is an association between it & end-stage hip OA. 
2. Prognostic study by Lievense et al., (2005) found 36% & 29% of 164 pt’s had Sx @ 1 & 5yr F/U respectively. Limitations included: a low f/u rate (54%), predisposing to selection bias & nil objective Ax; meaning GTPS pt’s were recruited based on subjective findings.
3. Current study included 3 groups. A GTPS (n=42), hip OA (n=20, all underwent THR in following 12/12), and asymptomatic (ASC, n=23). GTPS was Dx w a 3/12 Hx of lateral hip pain, POP of GT & pain w lying, weight bearing or sitting. Hip OA was Dx using the Altman criteria (1991).
4. At 11yr F/U: 35% of GTPS pt’s had developed hip OA & 45% continued to have GTPS Sx. None of the ASC had OA & only 5% had gone on to develop GTPS. The GTPS group had greater disability, weaker hip ABD & a slower TUG vs ASC.
5. This is the first long-term F/U study investigating the prognosis of GTPS, and the first to illustrate it may be associated with developing Sx hip OA. My thoughts on what could be some of the possible explanations for this includes…..
6. a) Reduced glute min/med strength secondary to tendinopathic changes may influence stability & control of the adductor moment @ the hip, leading to abnormal biomechanics.
7. b) The GTPS cohort had more comorbidities & a higher BMI vs ASC. Due to OA being a metabolic condition; we could hypothesise the raised systemic inflammation is likely to accelerate those arthritic changes.
8. c) As disability & function were affected, the GTPS pt’s may have been more sedentary. This may negatively influence cartilage turnover, systemic inflammation & increase the risk of further comorbidities & +BMI.
9. Limitations include; a) small sample size, b) variations in walking speed with the 10mwt & TUG & c) lack of imaging to fully confirm the diagnosis of GTPS & OA.
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