Are There Hidden Genes in DNA/RNA Vaccines? (2022)🔔🆕
frontiersin.org/articles/10.33…
🧬Some ORFs on SARS-CoV-2 DNA/RNA vaccines, could lead to the translation of undesired proteins during vaccination
🧬Pfizer and Moderna vaccines were analyzed
#sciencetwitter
(1/3)
frontiersin.org/articles/10.33…
🧬Some ORFs on SARS-CoV-2 DNA/RNA vaccines, could lead to the translation of undesired proteins during vaccination
🧬Pfizer and Moderna vaccines were analyzed
#sciencetwitter
(1/3)
(2/3)
Translation of overlapping ORFs within larger ORFs can result in harmful effects on host tissues, such as interfering with organelle membrane protein activity or perturbing signaling pathways
The protein-coding potential of DNA/RNA vaccines should be investigated further
Translation of overlapping ORFs within larger ORFs can result in harmful effects on host tissues, such as interfering with organelle membrane protein activity or perturbing signaling pathways
The protein-coding potential of DNA/RNA vaccines should be investigated further
(3/3)
Notably, the Moderna mRNA-1273 vaccine sequence is predicted to contain no frameshifted ORFs on the positive sense strand, which highlights the utility of codon optimization in DNA/RNA vaccine design to remove undesired overlapping ORFs 👍
Notably, the Moderna mRNA-1273 vaccine sequence is predicted to contain no frameshifted ORFs on the positive sense strand, which highlights the utility of codon optimization in DNA/RNA vaccine design to remove undesired overlapping ORFs 👍
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