This denarius was minted in 49 BC as Caesar crossed the Rubicon. Struck under the moneyer Manius Acilius Glabrio, we see Valetudo leaning on a column and holding a snake. Valetudo was the Roman equivalent of Hygieia, the Greek goddess of health and hygiene.. 
Glabrio was the stepson of Pompey the Great, raised in his house after Pompey married his mother Amelia Scaura. This coin was likely in support of Pompey, the idea being that he and the optimates were fighting to preserve the health (Salus) of the Republic as Caesar approached..
With Pompey's retreat, Caesar took control of Rome in 49 BC and seized large quantities of gold and silver from the state treasury in the Temple of Saturn - part of which may have been this newly minted issue by Glabrio.
Interestingly, Manius Acilius Glabrio is later attested as a lieutenant of Caesar in the civil wars and afterwards as a provincial magistrate, implying he switched allegiance after the death of his stepfather Pompey in 48 BC.
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