Max Niyazi Profile picture
Mar 3 4 tweets 3 min read
CCA - differentiation of reactive lesions from progressive ones following cranial radiotherapy - a thread 1/n

➡️ primary & secondary brain tumors (glioblastoma/brain mets)
➡️ after high dose radiotherapy
➡️ N=33, prospective confirmatory study

authors.elsevier.com/sd/article/S20…
➡️unclear findings on conventional MRI (psPD/RN vs PD)
➡️contrast clearance analysis with 1 h delayed CE MRI, images were substracted from each other
➡️ histopath confirmation
➡️ overall accuracy very high (84%)
➡️ subgroup of secondary tumors with high benefit (accuracy 94%!)
Therefore a potential new standard? Amino acid PET in a smaller subgroup did not outperform CCA @galldiks , perfusion/DWI more prone to institutional deviations/less potential to be standardized? @gminniti2012
Thanks to the excellent collaboration @LMU_Uniklinikum @LMU_RadOnc #Neuroradiology #Neurosurgery @R_Bodensohn @stef_corradini Robert Forbrig, Niklas Thon, Ulrich Mansmann, @BoulesteixLaure and many others and @Brainlab

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