Dr. Richard Corsi Profile picture
Mar 22 18 tweets 4 min read
1/ Very interesting study on effects of ozone on adolescent depression. The study focused on elevated ozone concentrations outdoors.
2/ Remember that ozone of outdoor origin penetrates into buildings and reacts with indoor materials & unsaturated organic compounds in indoor air to form a wide range of reaction products, many of which are lacking tox studies.
3/ When ozone is elevated outdoors or when (unfortunately) devices are used that generate ozone indoors, more of these indoor reactions occur.
4/ Note that ozone even reacts with unsaturated compounds, e.g., squalene, in our skin oils - whether still on us, shed into dust as skin flakes, or smeared onto indoor materials. These reactions also lead to by-products that we inhale.
5/ In a recent study of indoor air quality in schools we found that nearly 75% of all ozone consumption (by reactions) in classrooms is due to ozone reactions with human bodies and clothing in the classrooms.
6/ Because of these indoor reactions, ozone concentrations tend to be much lower indoors than outdoors. However, because of human activity patterns of Americans (we are indoor creatures) ....
7/ On average about 50% of our inhalation dose of ozone of outdoor origin occurs while we are indoors. Our dose is even higher if we use devices that emit ozone indoors (a bad idea).
8/ To reduce the inhalation of ozone and its reaction products, ozone can be removed from buildings using activated carbon filters (on air intake or downstream of recirculated air in HVAC systems) or in portable air cleaners.
9/ My former PhD student - Josh Aldred - did a dissertation on the topic of the costs and benefits of using activated carbon filtration for population health. The results were fairly striking for some types of buildings.
10/ Josh's complete dissertation is here:

A paper that summarizes major results is here: tandfonline.com/doi/full/10.10…
11/ We also had a graduate student (Donna Kunkel) who studied the use of activated carbon sleeves on ceiling fan blades and showed a substantial decrease in ozone concentrations in a test house when teh amended ceiling fan was activated. sciencedirect.com/science/articl…
12/ An alternative to activated carbon are passive removal materials that can be used over large areas that decompose ozone w/ minimal reaction product formation. This lowers ozone concentrations but also precludes more reaction products formed via reaction with other materials.
13/ We have found clay-based plasters & paints that contain kaolinite to be very effective at decomposing ozone w/ minimal reaction products formed. One of my ex-PhD students (Erin Darling) did excellent work in this area for her dissertation.
14/ Appropriate unfired clay bricks are also being used to preserve works of art & historical artifacts in Denmark, as clay also removes organic acids and other indoor gases from air.
15/ One of the reasons that I got into the indoor air quality field nearly 3 decades ago is because it held so much promise for innovation to make the places we spend the dominant fraction of our lives healthier.
16/ As I reflect back I see a lot of innovation from many without a substantial base of federal research funding afforded other fields.
17/ As I look forward I see a lot greater interest and potential funding for indoor air quality research. I hope that those new to the field will realize the successes of the past, build on them as opposed to repeat them, and make buildings better environments for all.

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More from @CorsIAQ

Mar 22
1/ Important study of over 10,000 classrooms.

Upshot = lowering concentration of virus-laden respiratory aerosol particles in classroom air lowers inhalation dose of these particles and significantly reduces infection. Always been about this, folks.

reuters.com/world/europe/i…
2/ Increasing ACH from lower than 2.4 to 2.4/hr - infections reduced by 40%. To 4 ACH lowered by 66.8%, to 6 ACH lower by 82.5%. With an appropriately-sized portable HEPA system or a #CorsiRosenthalBox we cannot achieve 10 ACH.
3/ "If the most efficient systems were installed "we could pass from 250 cases per 100,000 students (the alert level set by the education ministry) to a rate of 50 per 100,000."

Yep, its about lowering inhalation dose to virus-laden respiratory aerosol particles.
Read 9 tweets
Mar 18
1/ Almost 22 years ago I wrote an article for Environmental Manager entitled Indoor Air Quality: A Time for Recognition. I called for new clean air act amendments that address indoor air quality due to its profound impacts on human health.

pubs.awma.org/gsearch/em/200…
2/ From well before that article to the 22 years since I have tried to be a relentless advocate for formal recognition of indoor air quality and its importance, often feeling defeated, as I know many, many of my wonderful colleagues have as well.
3/ If there is a silver lining that has come out of this H*O*R*R*I*F*I*C pandemic, it's that the public has started learning of the importance of indoor air quality, from sources to the importance of engineering controls & how buildings are operated, constructed, and maintained.
Read 6 tweets
Mar 18
1/ A context slide from my CITRIS webinar on 3/16/22.

We know it is possible to achieve a CADR > 800 cfm for a Corsi-Rosenthal box. So, let's compare its impact in a realistic dorm room & classroom relative to air changes per hour in, say, a hospital infection isolation room.
2/ In a standard 2-person dorm room (where masks are unlikely to be worn when two people are sleeping 10 ft away from one another for 8 hours!) the CR box yields an aerosol particle reduction equivalent to 24 air changes per hour (ACH).
3/ Without any other ventilation, this is 2 x a hospital isolation room! Measurements of natural ventilation in my home garage with the large garage door wide open have been in the range of 15 to low 20s for ACH depending on outdoor wind conditions.
Read 12 tweets
Mar 16
1/ In the indoor air quality field, source removal (or avoidance of ever having the source in a space) is a fundamental principle.

“If there is a pile of manure in a space, do not try to remove the odor by ventilation. Remove the pile of manure.” Max von Pettenkofer (1858)
2/ During the pandemic that means doing all that's possible to avoid having infected persons in a space with others. Stay home if feeling symptoms. Test and isolate.
3/ If source removal is not possible, then source reduction becomes important. Lowering density lowers the probability of a source being present, but does not assure removal of source. Everyone wearing high-quality, e.g., N95, masks dramatically lowers source emissions.
Read 5 tweets
Mar 15
1/ Really excited to get this paper into the pipeline for peer review. See researchsquare.com/article/rs-143…

Involves a novel method to assess near- and far-field exposures using specific terpenoids/VOCs in breath mints & a PTR-ToF-MS. Teaser below for distance from human source.
2/ Results, of course, are limited to the specific chamber and ventilation assembly (27 m3 chamber at 3 ACH w/ top-down ventilation).
3/ For test conditions the results suggest relatively low multipliers (1.18, 1.11, 1.08) for 2.5 ft, 5 ft, 7.5 ft, respectively, relative to volume-averaged (chamber exhaust) concentration after approx 25 minutes.
Read 9 tweets
Mar 7
1/ 3 hours in the late night & a seed tossed into the social media wind. Origin of the #CorsiRosenthalBox.

There were 2 motivations for the concept.

Motivation 1. Make effective air cleaning more accessible to those who cannot afford $300 HEPA air cleaners.
2/ Motivation 2. Help schools employ effective air cleaning at a cost that would not be prohibitive given financial constraints. In summer 2020 school districts seemed overwhelmed, confused, & vulnerable to purchasing shiny objects that might not actually be all that effective.
3/ Three criteria were considered for the device:
(1) Effective, removing a reasonable amount of virus-laden aerosol particles from indoor air.
(2) Inexpensive, much lower cost than HEPA air cleaners.
(3) Open source, not a “money maker” for anyone or any organization.
Read 29 tweets

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