Getting to the Heart of Kidney Disease session moderated by @jenniejlin and @RupalMehtaMD first up: Medication Landscape in Cardio-Renal Disease Robert Lee Page Pharm D #NKFClinicals
Starts off with the pearl the heart pumps blood top the kidney. Now on to new heart failure guidelines using all the l pillars and you get 73% reduction in mortality #NKFClinicals
Level of evidence in CKD is pretty much absent. #NKFClinicals
Saying blocking the bradykinin is really helpful. He says the cough sucks but it really helps. #NKFClinicals
He is pushing lower doses of ACEi/ARB to increase tolerability. #NKFClinicals
Pushing ARNI, no longer need to start with ACEi/ARB prior to adding ARNI. Remember to washout any ACEi before starting secubitril to avoid terrible angioedema.
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Next up Implications of lower BP thresholds in patients with advanced CKD by Paul Drawz. Starts with a question
Effects of intensive BP lowering in patients with advanced CKD likely include:
A) Prevention of ESRD
B) Increased risk of AKI
C) Increased fall risk
D) Increased risk of infection
Next up fellow Channeler, @AnnaGaddy to talk about urine Chemistries to Predict and Monitor Response to Diuretics. She’s an Assistant Professor of Medicine. #NKFClinicals
Next up is Dr. Uribarri to savage the urinary anion gap. Sorry @Dan_Batlle.
The urine anion gap is not real, but allows you to see what is not measured. There is no gap. Cations must equal anions.
Since 24 urine Na, K, Cl equal their dietary intake, then the urine anion gap must reflect relative dietary intake not ammonia in the urine. #NKFClinicals