1. Does the explanation of biological phenomena require appealing to ๐ฒ๐บ๐ฒ๐ฟ๐ด๐ฒ๐ป๐ฐ๐ฒ? youtube.com/clip/UgkxjSerfโฆ
In Chapter 1 we said that biological systems realise ๐๐ก๐ค๐จ๐ช๐ง๐: a causal regime ๐ถ๐ฟ๐ฟ๐ฒ๐ฑ๐๐ฐ๐ถ๐ฏ๐น๐ฒ ๐ฎ๐ป๐ฑ ๐ฑ๐ถ๐๐๐ถ๐ป๐ฐ๐ from those at work in other physical and chemical natural systems, and thus an ๐ฒ๐บ๐ฒ๐ฟ๐ด๐ฒ๐ป๐ property.
2. ๐ง๐ต๐ฒ ๐ฝ๐ต๐ถ๐น๐ผ๐๐ผ๐ฝ๐ต๐ถ๐ฐ๐ฎ๐น ๐ฐ๐ต๐ฎ๐น๐น๐ฒ๐ป๐ด๐ฒ ๐๐ผ ๐ฒ๐บ๐ฒ๐ฟ๐ด๐ฒ๐ป๐ฐ๐ฒ
Philosophical work on emergence began in the late 19th century, with British emergentism. en.wikipedia.org/wiki/Emergentiโฆ
A central challenge to the idea of emergence is articulated in Kimโs ๐ฒ๐ ๐ฐ๐น๐๐๐ถ๐ผ๐ป ๐ฎ๐ฟ๐ด๐๐บ๐ฒ๐ป๐ link.springer.com/article/10.100โฆ
3. ๐๐ถ๐บโ๐ ๐ฒ๐ ๐ฐ๐น๐๐๐ถ๐ผ๐ป ๐ฎ๐ฟ๐ด๐๐บ๐ฒ๐ป๐: definitions
For a whole W composed of parts Pi, each with properties Ni
๐ฆ๐๐ฝ๐ฒ๐ฟ๐๐ฒ๐ป๐ถ๐ฒ๐ป๐ฐ๐ฒ: If property M emerges from properties Ni, then M supervenes on Ni
๐๐ฟ๐ฟ๐ฒ๐ฑ๐๐ฐ๐ถ๐ฏ๐ถ๐น๐ถ๐๐: Property M is emergent from a set of properties N1, โฆ, Nn only if M is not functionally reducible with the set of the Ns as its realiser. #definitions
If an emergent property M is supervenient on some basal conditions P, and M is said to cause some effect, one may ask ๐ฌ๐๐ฎ ๐๐๐ฃ๐ฃ๐ค๐ฉ ๐ ๐๐๐จ๐ฅ๐ก๐๐๐ ๐ as a cause of any putative effect of M?โ
5. ๐๐ถ๐บโ๐ ๐ฒ๐ ๐ฐ๐น๐๐๐ถ๐ผ๐ป ๐ฎ๐ฟ๐ด๐๐บ๐ฒ๐ป๐: Problems
๐๐๐ช๐จ๐๐ก ๐๐ง๐๐๐ฃ๐๐๐: if the causal powers of an emergent entity can be reduced to those of its constituents, and if, as may indeed be the case, there is no โrock-bottomโ level of reality, then...
...causal powers would "drain away into a bottomless pit and there would not be any causation anywhere". It'd be turtles over turtles all the way down...
additionally, if there were actually a rock-bottom, the exclusion argument would ๐ณ๐ผ๐ฟ๐ฐ๐ฒ ๐ฟ๐ฒ๐ฑ๐๐ฐ๐๐ถ๐๐ฒ ๐ฝ๐ต๐๐๐ถ๐ฐ๐ฎ๐น๐ถ๐๐บ, and any appeal to distinctively biological causal relations would be at best a heuristic tool...
6. Against Kim's exclusion argument, Moreno & Mossio provide an argument for closure being a specific kind of higher-level ๐ฒ๐บ๐ฒ๐ฟ๐ด๐ฒ๐ป๐ configuration, ๐ผ๐ป๐๐ผ๐น๐ผ๐ด๐ถ๐ฐ๐ฎ๐น๐น๐ ๐ถ๐ฟ๐ฟ๐ฒ๐ฑ๐๐ฐ๐ถ๐ฏ๐น๐ฒ.
Their argument is two-fold:
1) closure can be consistently understood as an ๐ฒ๐บ๐ฒ๐ฟ๐ด๐ฒ๐ป๐ ๐ฟ๐ฒ๐ด๐ถ๐บ๐ฒ ๐ผ๐ณ ๐ฐ๐ฎ๐๐๐ฎ๐๐ถ๐ผ๐ป all while staying strongly committed to ๐บ๐ผ๐ป๐ถ๐๐บ.
2) An emergent closed organisation ๐ฑ๐ผ๐ฒ๐๐ปโ๐ ๐ฟ๐ฒ๐พ๐๐ถ๐ฟ๐ฒ ๐ถ๐ป๐๐ฒ๐ฟ-๐น๐ฒ๐๐ฒ๐น ๐ฐ๐ฎ๐๐๐ฎ๐๐ถ๐ผ๐ป (specifically, nested causation, i.e., causation from the whole into its own parts).
7. ๐๐ฟ๐ฟ๐ฒ๐ฑ๐๐ฐ๐ถ๐ฏ๐ถ๐น๐ถ๐๐ ๐๐ฒ๐ฟ๐๐๐ ๐ป๐ผ๐ป-๐ฑ๐ฒ๐ฟ๐ถ๐๐ฎ๐ฏ๐ถ๐น๐ถ๐๐
Importantly, they argue that closure is ๐ถ๐ฟ๐ฟ๐ฒ๐ฑ๐๐ฐ๐ถ๐ฏ๐น๐ฒ and not only ๐ป๐ผ๐ป-๐ฑ๐ฒ๐ฟ๐ถ๐๐ฎ๐ฏ๐น๐ฒ (this will have consequences for distinguishing self-maintenance from closure)
A ๐ป๐ผ๐ป-๐ฑ๐ฒ๐ฟ๐ถ๐๐ฎ๐ฏ๐น๐ฒ property of a whole is one that cannot be ๐ฉ๐ซ๐๐๐ข๐๐ญ๐๐ or ๐๐ฑ๐ฉ๐ฅ๐๐ข๐ง๐๐ from the properties of its parts.
For example, the property of "containing" is not found on any of the sides of a box.
Non-derivability is ๐ฒ๐ฝ๐ถ๐๐๐ฒ๐บ๐ผ๐น๐ผ๐ด๐ถ๐ฐ๐ฎ๐น: it denotes a difficulty for predicting or explaining a property, whereas irreducibility is ๐ผ๐ป๐๐ผ๐น๐ผ๐ด๐ถ๐ฐ๐ฎ๐น: the entities produced are of a completely new kind.
Non-derivability is a characteristic of ๐ฟ๐ฒ๐๐๐น๐๐ฎ๐ป๐ properties, which are ๐ฎ๐ด๐ด๐ฟ๐ฒ๐ด๐ฎ๐๐ถ๐๐ฒ, i.e., the whole possesses it at values that the parts do not.
Irreducible emergent properties are of a kind that only the whole possesses.
8. ๐๐ฟ๐ฟ๐ฒ๐ฑ๐๐ฐ๐ถ๐ฏ๐ถ๐น๐ถ๐๐ ๐ฎ๐ป๐ฑ ๐ฒ๐บ๐ฒ๐ฟ๐ด๐ฒ๐ป๐ฐ๐ฒ
The core of Moreno & Mossio's argument for irreducible emergence of closure relies on distinguishing between ๐๐๐ฝ๐ฒ๐ฟ๐๐ฒ๐ป๐ถ๐ฒ๐ป๐ ๐ฏ๐ฎ๐๐ฒ and ๐ฒ๐บ๐ฒ๐ฟ๐ด๐ฒ๐ป๐ฐ๐ฒ ๐ฏ๐ฎ๐๐ฒ of a property.
For this, they define ๐ฟ๐ฒ๐น๐ฎ๐๐ถ๐ผ๐ป๐ฎ๐น ๐๐๐ฝ๐ฒ๐ฟ๐๐ฒ๐ป๐ถ๐ฒ๐ป๐ฐ๐ฒ: a supervenience relation holding between the whole and a ๐ฐ๐ผ๐ป๐ณ๐ถ๐ด๐๐ฟ๐ฎ๐๐ถ๐ผ๐ป of its constituents. #definition
This ๐ฟ๐ฒ๐น๐ฎ๐๐ถ๐ผ๐ป๐ฎ๐น point of view argues that ๐ฐ๐ผ๐ป๐ณ๐ถ๐ด๐๐ฟ๐ฎ๐๐ถ๐ผ๐ป๐ C have their own properties, distinct from those of their components (the parts P)
This is a ๐ฐ๐ผ๐ป๐๐๐ถ๐๐๐๐ถ๐๐ฒ interpretation of relational supervenience: supervenient properties can be reduced to ๐ฐ๐ผ๐ป๐ณ๐ถ๐ด๐๐ฟ๐ฎ๐๐ถ๐ผ๐ป properties (but not to the properties of the parts)
Moreno and Mossio then argue that emergent properties do not emerge from configurational properties, but between configurational properties and the properties of different categories and entities which do not belong to the configuration (the parts or individual processes)
9. ๐ฆ๐๐ฝ๐ฒ๐ฟ๐๐ฒ๐ป๐ถ๐ฒ๐ป๐ฐ๐ฒ ๐ฎ๐ป๐ฑ ๐ฐ๐ผ๐ป๐๐๐ถ๐๐๐๐ถ๐ผ๐ป
Kim argues that emergent properties are micro-based macro properties.
Here, the supervenient property M has causal powers relative to the parts Pi, but not relative to the properties S of the configurations of parts Ni
The supervenient property M is ๐ฐ๐ผ๐ป๐๐๐ถ๐๐๐๐ฒ๐ฑ by the properties Si of the configurations โ they are equivalent.
M&M's reply to Kim's exclusion argument
is that it is the relational properties Si of configurations which are genuinely emergent: the properties Si of the configuration C are irreducible to any entity that does not possess the same Si.
It is ๐ฟ๐ฒ๐น๐ฎ๐๐ฒ๐ฑ๐ป๐ฒ๐๐ ๐๐ต๐ฎ๐ ๐ฏ๐ฟ๐ถ๐ป๐ด๐ ๐ผ๐ป๐๐ผ๐น๐ผ๐ด๐ถ๐ฐ๐ฎ๐น ๐ป๐ผ๐๐ฒ๐น๐๐, by stating that configurations may possess distinct causal powers. M is constituted by Si, and Si emerges from configurations of the parts Pi.
11. ๐๐ผ๐ป๐๐๐ฟ๐ฎ๐ถ๐ป๐๐ ๐ฎ๐ป๐ฑ ๐๐น๐ผ๐๐๐ฟ๐ฒ ๐ฎ๐ ๐๐บ๐ฒ๐ฟ๐ด๐ฒ๐ป๐ ๐๐ฒ๐๐ฒ๐ฟ๐บ๐ถ๐ป๐ฎ๐๐ถ๐ผ๐ป๐
The reply refers to 3 kinds of emergent bases:
1. ๐ฆ๐๐ฏ๐๐ฒ๐ (Psset): The configuration C is emergent on any proper subset of the parts
2. ๐ฆ๐๐ฏ๐๐๐ฟ๐ฎ๐๐ฒ (Psstr): C is emergent on a collection of its constituents taken separately (potential ingredients) 3. ๐ฆ๐๐ฟ๐ฟ๐ผ๐๐ป๐ฑ๐ถ๐ป๐ด๐ (Psurr): C is emergent on external elements that do not constitute C, even if they share the same spatial localisation.
12. Constraints are configurations that exert causal actions on processes while being conserved with respect to them. In other terms:
1) At a relevant scale ๐, a constraint is a configuration Cconstr exerting a causal action on Psurr, which produces an observable difference between Psurr and Psurr^C (i.e., the surrounding parts alone, or under the effect of the constraint C)
2) At the same scale ๐, Cconstr is conserved throughout Psurr. Its emergent properties Si remain unaffected throughout Psurr.
A ๐ฐ๐น๐ผ๐๐ฒ๐ฑ organisation is a configuration Corg constituted of configurations Cconstr. Then: 1) closure is ๐ถ๐ฟ๐ฟ๐ฒ๐ฑ๐๐ฐ๐ถ๐ฏ๐น๐ฒ to Psurr, 2) closure is ๐ฒ๐บ๐ฒ๐ฟ๐ด๐ฒ๐ป๐ relative to Psstr,
14. ๐๐ป๐๐ฒ๐ฟ-๐น๐ฒ๐๐ฒ๐น ๐ฐ๐ฎ๐๐๐ฎ๐๐ถ๐ผ๐ป
After arguing that closure is an irreducible emergent property, M&M discuss the type of inter-level causation that can be at play.
Downward causation ๐ผ๐ป ๐ฎ ๐ฑ๐ถ๐ณ๐ณ๐ฒ๐ฟ๐ฒ๐ป๐ ๐ฒ๐ป๐๐ถ๐๐ located at a lower level is widespread and unproblematic. This definition applies straightforwardly to self-maintenance and closure. Weโll call this ๐ป๐ผ๐ป-๐ฟ๐ฒ๐ณ๐น๐ฒ๐ ๐ถ๐๐ฒ ๐ฐ๐ฎ๐๐๐ฎ๐๐ถ๐ผ๐ป. #definition
15. On the contrary, downward causation exerted by the system ๐ผ๐ป ๐ถ๐๐ ๐ผ๐๐ป ๐ฐ๐ผ๐ป๐๐๐ถ๐๐๐ฒ๐ป๐๐ is more controversial. This is what Kim calls ๐ฟ๐ฒ๐ณ๐น๐ฒ๐ ๐ถ๐๐ฒ ๐ฑ๐ผ๐๐ป๐๐ฎ๐ฟ๐ฑ ๐ฐ๐ฎ๐๐๐ฎ๐๐ถ๐ผ๐ป.
16. There are various interpretations of reflexive causation.
๐๐ผ๐ฟ๐บ๐ฎ๐น causation (like in Aristotle's formal cause), where the whole exerts a constraining action on its own constituents, may be the standard interpretation. nbi.dk/~emmeche/coPubโฆ
For ex., in a wheel rolling downhill no single molecule is enough to explain the rolling movement, only the form of the whole wheel can.
This is a case of ๐ฒ๐ฝ๐ถ๐๐๐ฒ๐บ๐ผ๐น๐ผ๐ด๐ถ๐ฐ๐ฎ๐น ๐ป๐ผ๐ป-๐ฑ๐ฒ๐ฟ๐ถ๐๐ฎ๐ฏ๐ถ๐น๐ถ๐๐, and rolling can be seen as a ๐ฟ๐ฒ๐๐๐น๐๐ฎ๐ป๐ property.
17. Moreno & Mossio are interested, however, in the ๐ผ๐ป๐๐ผ๐น๐ผ๐ด๐ถ๐ฐ๐ฎ๐น๐น๐ ๐ถ๐ฟ๐ฟ๐ฒ๐ฑ๐๐ฐ๐ถ๐ฏ๐น๐ฒ type of reflexive downward causation, which they call ๐ป๐ฒ๐๐๐ฒ๐ฑ ๐ฐ๐ฎ๐๐๐ฎ๐๐ถ๐ผ๐ป to be more precise.
18. They argue that ๐ป๐ฒ๐๐๐ฒ๐ฑ ๐ฐ๐ฎ๐๐๐ฎ๐๐ถ๐ผ๐ป ๐ถ๐ ๐ป๐ผ๐ ๐ฟ๐ฒ๐พ๐๐ถ๐ฟ๐ฒ๐ฑ in biology, because no nested causation can exist between an emergent property and its own supervenience base: config. properties Si do not produce M, and M does not exert downward causation on Si.
19. In particular, the closed organisation Corg does not exert causation on the whole network of constitutive constraints, and the whole network of constitutive contraints does not produce the closed organisation.
20. Letโs consider the different emergent bases one by one and ask: is there need for nested causation between Corg and 1) ๐ฆ๐๐ฏ๐๐ฒ๐ (Psset)? No, since the properties of each Psset are already configurational, then redundant.
2) ๐ฆ๐๐ฏ๐๐๐ฟ๐ฎ๐๐ฒ (Psstr)? No, because the collection of constituents, taken without their configurational properties, is an abstract description which do not correspond to the way in which constituents are organised in the system
3) ๐ฆ๐๐ฟ๐ฟ๐ผ๐๐ป๐ฑ๐ถ๐ป๐ด๐ (Psurr)? No, because surroundings are by definition external to the configuration.
21. Moreno and Mossio conclude that constraints do exert causal powers, but not in the form of nested causation.
This has ๐ฎ ๐ฐ๐ฟ๐๐ฐ๐ถ๐ฎ๐น ๐ฐ๐ผ๐ป๐๐ฒ๐พ๐๐ฒ๐ป๐ฐ๐ฒ๐ for the interpretation of self-maintenance and closure:
1) ๐ฆ๐ฒ๐น๐ณ-๐บ๐ฎ๐ถ๐ป๐๐ฒ๐ป๐ฎ๐ป๐ฐ๐ฒ. Consider the case of Bรฉnard cells: an interpretation based on nested causation would claim that each cell constraints its own constituents. youtube.com/clip/UgkxWXvRkโฆ
But in relational terms, the cell ๐๐จ the configuration. One is tempted to think there's nested causation because the behaviour of each molecule within the cell is under-determined. This confuses epistemological non-derivability and ontological irreducibility.
2) ๐๐น๐ผ๐๐๐ฟ๐ฒ: what would justify nested causation? Here, self-maintenance is realised collectively by a network of mutually dependent constraints. Constraints seem to act on processes which are already inside the system.
Although this considers the constrained processes as constituents of the organisation, they are not: in biological systems, the ๐ฐ๐ผ๐ป๐๐๐ถ๐๐๐ฒ๐ป๐๐ of the ๐ผ๐ฟ๐ด๐ฎ๐ป๐ถ๐๐ฎ๐๐ถ๐ผ๐ป ๐ฎ๐ฟ๐ฒ ๐๐ต๐ฒ ๐ฐ๐ผ๐ป๐๐๐ฟ๐ฎ๐ถ๐ป๐๐ ๐๐ต๐ฒ๐บ๐๐ฒ๐น๐๐ฒ๐, ๐ป๐ผ๐ ๐๐ต๐ฒ ๐ฝ๐ฟ๐ผ๐ฐ๐ฒ๐๐๐ฒ๐.
22. In conclusion, constraints are configurations that by virtue of the relations existing between their own constituents possess emergent properties enabling them to exert distinctive causal powers on their surroundings.
23. And closure as an emergent and irreducible causal regime does not need to invoke nested causation.
1. The particular type of causal regime at work in biological organisation is ๐พ๐ก๐ค๐จ๐ช๐ง๐. It combines:
* An open thermodynamic regime, and
* A closed organisation regime of ๐๐ค๐ฃ๐จ๐ฉ๐ง๐๐๐ฃ๐ฉ๐จ
2. ๐ฝ๐๐ค๐ก๐ค๐๐๐๐๐ก ๐๐๐ฉ๐๐ง๐ข๐๐ฃ๐๐ฉ๐๐ค๐ฃ ๐๐จ ๐จ๐๐ก๐-๐๐ค๐ฃ๐จ๐ฉ๐ง๐๐๐ฃ๐ฉ
Closure can be defined in different contexts:
i. In general, a domain K is said to have closure if all operations defined in it remain within the same domain.
1. The main question of the book is how to characterise life?
A fundamental problem is the tension between the principle of continuity from inert to living, and the obvious differences between them.
2. Mainstream thinking emphasises the role of evolution and adaptation, i.e., the history of changes, but forgetting the organism, which becomes almost *dispensable*.
Brain folds develop together with cytoarchitectonic regions and corticocortical connections. That folding results from a mechanical instability is now relatively well accepted. However, the pattern of these folds is still thought to reflect patterned gene expression #ohbmx
2
Indeed, a genetic program could encode regionalisation, connectivity and folding patterns. But what if folding *patterns* were of mechanical origin too? That would mean that mechanics have a causal role in the development and evolution of brain organisation! #ohbmx
3
One hint at the mechanical origin of folding patterns comes from observations made across primate species. Brains of phylogenetically distant species but with similar volume tend to have similar folding patterns despite their common ancestor being likely lissencephalic #ohbmx