#NWBO As a physician, there is several reasons why the idea of DCVax-L is exciting. #1. Patient compliance for medication in general is about 50-60%. The higher the side effect profile or burden of treatment, the lower the the compliance rate. DCVax-L immense advantage here.
You know who else hates side effects? Physicians. So when a treatment is given as an intradermal injection (high and known compliance) with such a low side effect profile, its something I am very excited about.
#2. After regulatory approval, you have to ask yourself, will neuro surgeons, neuro oncologist, oncologists be prescribing DCVax-L to their patients? Community physicians typically follow the lead of major academic institutions and thought leaders in their field. See prior post
An impressive list of institutions were involved in this trial.
#3. DCVax will be the foundation for which immuno suppressive combination will likely improve survival per Liau's lectures. Big pharma would love nothing more than to find new indications for their existing medications with upcoming patent cliff.
If you have not read the Pazdur annal of oncology paper in its entirety, I suggest you do, it will make you feel more assured about FDA authorization.
Like I have said before, the price drops do not scare me, it only allows for greater value.
• • •
Missing some Tweet in this thread? You can try to
force a refresh
#NWBO, Re-reading 2018 DCVax-L interim results and actually took the time to look at the authors and where they are all from.
Liau - UCLA
Ashkan - King College
Tran - University of Floria
Campian - Washington University
Trusheim - Abbott NW Hospital
Cobbs - Swedish Medical Center
Heth - University of Michigan
Salacz - University of Kansas Cancer Center
D’Andre - Sutter Institute
Iwamoto - Columbia University
Dropcho - Indiana University Simon Cancer Center
Moshel - Overlook Medical Center
Walter - University of Rochester
Pillainayagam - Rush University Medical Center
Aiken - Rutgers Cancer Institute
Chaudhary - University of Cincinnati Medical Center
Goldlust - Hackensack University Medical Center
Bota - UC Irvine
Duic - Winthrop University
Grewal - NYU Winthrop
Elinzano - Rhode Island Hospital