Kath Profile picture
May 27 7 tweets 2 min read
How mRNA vaccines work, oversimplified:
It's a mRNA string that instructs yr own cells to create a spike protein that is highly similar to the spike protein outside the SARS-COV-2 virus. This is the new part. The mRNA is gone in hours, & the spike proteins are gone in days.
1/?
Yr immune system sees the spike proteins, & develops immunity to them. That's the part that's like any other vaccine (& a lot like any actual infection too).
Later on, if & when yr immune system sees SARS-COV-2 spikes, it attacks. That's how all acquired immunity works.
2/?
How it's different from other vaccines: having yr own cell build the antigen, instead of having it injected (or in some cases swallowed). That's all that's different. And remember, building things according to mRNA instructions is what cells do.
3/?
How it's different from other vaccines cont'd: the mRNA string is artificially created & stabilized (hence the cold storage). It's in a lipid package, (& a few might be allergic to it). But it doesn't need or have the adjuvants that an ordinary killed-virus vaccine needs.
4/?
How it's different from infections: the spikes aren't multiplying inside yr body as a virus would, so you're not getting an actual infection, so you don't mount much of a primary immune system response, & you won't get dangerously ill.
5/?
How it's different from infections (cont'd): you're not shedding infectious virus so you're not contagious. Also, the spike is slightly different from a real SARS-COV-2 spike. It's been altered to make it less dangerous to yr body. This is a good thing.
6/7
This thread was meant as a reply over on The Thread From Hell (I didn't want to clutter up everyone's convo w/ a 7-tweet string).
IANAD or HCW, & This Is Not My Field.
Consult yr medical provider for reliable info.
This is just an oversimplified explanation for laypeople.
7/7

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