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May 31 • 9 tweets • 3 min read
Many beautiful things happened at #apschi22 I’ll post about another time, after a bit of sleep. For now, just a few impressions of a stunning city. Image
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More from @EikoFried

Eiko Fried Profile picture
Jun 2
"Studying mental health problems as systems, not syndromes" online now. It's a short piece that I substantially rewrote in the last 6 months, and I think it has much improved. 1/19

psyarxiv.com/k4mhv
The paper tackles to barries to progress in understanding, predicting, and treating mental health (abbreviated as "MH" from here on) problems, and suggests ways forward.

The two core roadblocks are diagnostlic literalism and reductionism. /2
First: *diagnostic literalism*, mistaking diagnoses for MH problems. I explain the differences between these 2 classes of things in detail using language from philosophy of science, & many examples other nosologies or taxonomies (e.g. chemical elements, biological species) /3
Read 20 tweets
Eiko Fried Profile picture
May 12
You may remember the recent NatureMedicine paper where authors claim to show—as the first author says below—that psilocybin "liberates the entrenched depressed brain". This led to considerable news coverage.

3 pretty remarkable things have happened since this was published 🧵
1/ First, authors have admitted they switched away from the registered primary outcome.
The justification reads like a clear concession of p-hacking to me: we did it because it worked better. Maybe I am missing something—curious how others see this.

psyarxiv.com/pdbf5/
2/ Second, in response to criticism of multiple testing & 1-sided tests, the authors appear to straight-up admit to doing something that, at least in my area of research, is considered by many a questionable research practice.

Thoughts?
Read 7 tweets
Eiko Fried Profile picture
May 9
Got a new macbook & spent some time setting up a few useful apps I like. Some of them cost a little money, but the features were worth it for me.

A little 🧵

(COI: none, I am not involved in any of these apps or get anything for mentioning them here)
1/ Middleclick
Allows you to middle mouse click on touch pad and magic mouse by clicking with 3 fingers as a default. I use middle click a lot eg. to close browser tabs, so quite useful for me.
2/ BetterSnapTool
Move and snap windows. ImageImage
Read 7 tweets
Eiko Fried Profile picture
Apr 19
🔥 Folks—there's a new paper in town, and I'd love to tell you about it. In the paper I wrote with @JkayFlake & Don Robinaugh, we take a bird's eye view on depression measurement. History, present, future. In particular, we discuss shaky theoretical & methodological foundations🧵
2/ Paper in one tweet:
Limited progress in depression research is in part due to the lack of focus on measurement. We review the many problems with depression measurement, including validity and reliability. We discuss shaky methods & theory foundations, & provide paths forward
/3 Two tweets on how the paper came to be.

Don was my office mate in 2016, & encouraged me to write what he jokingly called my "manifesto" on depression measurement, given that a lot of my work was focused on that topic at the time. I started the first draft back then.
Read 29 tweets
Eiko Fried Profile picture
Apr 19
Tweeps: switched from Android to iOS half a year ago for more consistent app use w my MacBook. Happy w switch but struggle with some stuff. There must be easy solutions, maybe y'all can help. Thanks! 🧵
1/ Swiping from bottom up (to see bluetooth, wifi, torch) works only v inconsistently in some apps like WhatsApp; it keeps recognizing text inputs on the keyboard ("xsdfjh") instead of swiping up. Am I just bad at swiping?
2/ Incoming photos are all put into the main folder. There are separate folders for e.g. whatsapp, but whatsapp photos all also go into the core folder. As a result there is no folder with just photos I took. Help.
Read 6 tweets
Eiko Fried Profile picture
Apr 12
BBC global news @BBCWorld podcast: “could magic mushrooms be a powerful new cure for mental illness?”

Unfortunately, this is very unlikely. Here’s why. 🧵
1/ The scientific literature so far is full of big problems. First, scientific studies often lack a control group, which is an issue because it leaves open the question whether mushrooms work better than placebo.
/2 Second, if studies have a control group, participants often know in which group they are in (it’s obvious if you get mushrooms or a placebo). This is a big problem. New studies try to work around this, but the evidence so far is largely based on non-blind studies.
Read 10 tweets

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