Not overlooked, but ignored because I don’t wish to further amplify it. But here’s a quick summary:
Like many of his fellow economists with Ivy League credentials but no specific expertise in biology, he suffers from the delusion that he knows what the fuck he’s talking about.
Jeff Sachs is the chair of @TheLancet COVID-19 Commission. This isn’t an official government board with any real mandate. It’s just a prestigious medical journal deciding to make up a task force of prestigious people to write more prestigious content for said prestigious journal.
The Lancet COVID-19 Commission will issue a bunch of reports that are glorified opinion pieces stating the obvious: we weren’t prepared for the pandemic, there are massive inequities, it had huge global impact, need more vaccines/infrastructure, etc.
Some academics will care.
Ultimately The Lancet COVID-19 Commission is an official-sounding name for what is effectively academic busywork for a bunch of smart, well-decorated people & a marketing ploy for an elite journal. Nobody asked Lancet to convene a “commission” & their recs carry no policy weight.
Sachs is a famous Ivy League dude who writes lots of books, makes big, global, society-wide pronouncements, & hangs w/ other famous guys, so he’s a perfect choice to chair.
And since it’s made up for prestige, it doesn’t matter that he knows fuck all about viruses or pandemics.
So he’s had a rough ride with the part of The Lancet: COVID-19 Commission dealing with SARS-CoV-2 origins. It was first chaired by Peter Daszak—so anyone following origins topics on Twitter for 2 seconds can imagine how that went.
Sachs disbanded the group, purportedly for COI.
Sure, fine, no problem, because it’s a toothless committee anyway. Sachs said he was going to revisit the topic w/ the executive commissioners & some experts.
Unfortunately those “experts” included some very non-experts, prompting actual experts to stop wasting their time on it.
The non-expert “experts” included a well-known grifter with a lab leak fantasy fiction book to sell & several academics who have been chronically dishonest about their subject matter expertise in service of self-promotion and advancing their agendas.
This includes Richard Ebright, the human manifestation of Pepe the Frog, who spends his days squatting on his Twitter lily pad croaking at everyone who disagrees w/ his uninformed views on biosafety, virology, & evolution that they are shills, stooges, & thralls of the CCP.
Feel free to lecture me about professionalism here & get blocked w/ a quickness. I gave a talk on Twitter disinfo & had an entire slide cataloguing every time he called someone (inc me) a stooge in the prior 2 weeks. He’s an abusive bigot & I don’t owe him professional courtesy.
It is an eternal truth that powerful men in academia resolutely ignore the bad behaviour of other powerful dudes they vibe with, so Sachs didn’t bother to note what a loathsome crank Ebright is. And I guess he didn’t check into his COI, since he’s overtly a lab leak zealot.
Instead, Sachs took a shine to him and basically accepted Ebright’s “expertise” as gospel.
Ebright is a professor of chemistry who studies bacterial transcription. He is not an expert on viruses in any way, despite Sachs’ insistence that he is “very senior”.
So recently Sachs & a coauthor at Columbia (also not a virologist) wrote a perspective in PNAS. After making some uncontroversial calls for independent investigations, the paper takes a sharp turn and gets into some serious furin cleavage site trutherism.
The perspective argues that researchers at EcoHealth Alliance, the Wuhan Institute of Virology, & the University of North Carolina colluded to insert the furin cleavage site from a human gene called ENaC into a bat CoV—et voila, SARS-CoV-2.
This is speculative and based on a leaked grant proposal from 2018…a grant that was not funded. That grant suggests experiments to look at FCS function in bat CoVs and never mentions ENaC, and again it was not funded. There is zero evidence that these experiments were ever done.
Why ENaC? Well, Richard Ebright did a BLAST search and found a short string of identical amino acids and also sleuthed out there are cystic fibrosis researchers at UNC who study ENaC as well as others who study CoV pathogenicity and…WHAT A COINCIDENCE
BTW there’s no evidence that anyone at UNC was sourcing FCS sequences from the human genome or trying to make chimeric viruses with it—ENaC is involved in cystic fibrosis and that was the context in which it was studied at UNC.
So suddenly idle, baseless speculation becomes “questions” and those questions become “evidence.” That gets picked up by media outlets who have been uncritically parroting poorly fact checked lab leak talking points for months.
And guess which experts get interviewed to help elevate speculation to evidence with some scientific insight? Not-virologist Richard Ebright, who does some hand waving about coincidence to invite the reader to follow him down this conspiratorial rabbit hole.
I’ll add here he never mentions his own conflicts, starting with the fact that he alone advised Sachs on this particular theory & basically ghost wrote the PNAS piece or that he came up with the idea in his ceaseless quest to prove a lab origin without a shred of actual evidence.
(I will add that I’m particularly proud of the tweets that the Intercept piece pulled to make me look like a mean spirited bitch, though. I maintain that bad actors exploiting uncertainty during a global health crisis to promote personal interest over science is indeed ghoulish).
And to be clear about my conflicts and expertise, here’s my latest contribution to origins research. An original article about a scientific investigation undertaken by a team of independent experts in virology & viral evolution, currently undergoing peer review.
However, Sachs has not acknowledged that this work, which shows actual evidence that the pandemic started at the Huanan market through at least 2 zoonotic transmission events, even exists & is making the media rounds promoting this ENaC theory as new “evidence”.
But opinions are not evidence and they do not stand up to scientific scrutiny. Scientists, like all people, have opinions but at the end of the day our work is judged by what our data shows, not our opinions or speculation about it.
My coauthors & I have answered the call for an independent, evidence-based investigation into origins. There’s more to be done.
It’s a pity that Sachs has chosen to wield his influence so irresponsibly & has not himself committed to the objective inquiry he demands.
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Have I ever mentioned how surreal it is to be an Editor-in-Chief of a journal called Vaccine right now?
It’s pretty wild, at least by typical academic journal editorial office standards.science.org/content/articl…
Last Nov, the FDA’s top vaccine regulator forced FDA scientists to withdraw a paper from review because it showed that COVID vaccines work for all ages. Papers in Vaccine have been cited selectively by RFK Jr to mislead the public about vaccines. Now Vaccine is in the news again
I will always be grateful for opportunities to emphasize the integrity of our editorial & peer review practices & to invite authors to submit their work—especially if it contributes to a larger scientific debate or has a major impact on our field, public health, or society.
As the accursed ostrich situation continues to get simultaneously more stupid and gravely serious, I decided to write up a very long analysis of many of the key issues. Bottom line: so long as this flock lives, it is a threat to Canada's national security. 🧵
5 months ago I was scrolling & came across some tweets from @sisuvanhell that was my first exposure to the far-right extremist ostrich convoyers. They accused CFIA of sending "murder drones" to covertly cull their flock of ostriches after a H5N1 outbreak open.substack.com/pub/rasmussenr…
In Dec 2024, Universal Ostrich Farms had a confirmed H5N1 outbreak on their remote farm in BC. They did not report to CFIA as required by law. They lost 69 ostriches. CFIA found out anyway & tested 2 dead ostriches. They were positive. They issued a depopulation (cull) order.
This is interesting. The BC ostrich farmers have consistently misrepresented the “scientific research” they were conducting, but it seems they also may have not been entirely truthful about their ostrich meat, oil, & leather business, as well 👇🏻
The ostrich farm claims they are a scientific research facility to study ostrich antibodies. Birds have antibodies in their egg yolks & ostrich eggs are huge, so you can get a lot of antibodies from them. The farmers implied they were studying antibodies to COVID & flu.
But there’s nothing to show that’s true. They’ve never published a paper on the research or shared data/results. There’s a difference between doing research & producing antibodies to sell. According to court documents, they were producing eggs for the latter purpose.
I am always happy to talk to reporters like Nancy MacDonald @globeandmail covering the BC bird flu ostrich story with objectivity & a focus on the evidence.
I hope this clarifies why I think the cull of these birds should proceed whether they are tested or not. Short thread 🧵
The thing people need to realize is that, although the ostriches were infected 10 mo ago, they still pose a health risk & a HUGE economic risk. If CFIA spares them, Canada will violate trade agreements, jeopardizing the entire $2B poultry export market.
CFIA is responsible for ensuring the safety & health of Canadian people & animals by regulating agriculture & food. A big part of the agricultural mandate is to ensure compliance with trade partners' import requirements, to maintain trade. inspection.canada.ca/en/animal-heal…
I'm not uncomfortable with an interview. I don't wish to contribute to anti-government extremist propaganda that imposes the will of a few on Canada's health, food security, economy, & $2B poultry export market. I believe in upholding the law.
1. You can test these ostriches for antibodies. To do it reliably you need to do either a microneutralization or a hemagglutinin inhibition (HAI) assay. These require a high containment lab & trained personnel with HPTA security clearance because they use live virus.
Not many labs in Canada can do these tests. You can't do ELISAs due to cross-reactivity across other flu subtypes. Many overlapping subtypes circulate in birds (H5Nx; HxN1) & humans (H1N1). So you can't just measure antibody binding by ELISA, you must do HAI or microneuts.