New paper!

We introduce #GAMs as a tool for analysing medical monitoring data. We also present the idea that GAMs can be used to decompose a medical waveform into individual, physiologically relevant, components.

w/ @ucfagls and @SimonTVistisen…
Example 1: Pulse pressure ("the strength of a heart beat") varies with ventilation (mechanical). We can use a cyclic spline to represent the repeating effect of ventilation on pulse pressure. The smooth effect of respir...
This is especially useful when we only have a few beats per ventilation (high respiratory rate, low heart rate), where the pulse pressure variation in any individual ventilation does not represent the "true" pulse pressure variation. The smooth effect of respir...
Example 2: A steady central venous pressure (CVP) curve can be decomposed into separate cyclic effects: heart cycle, respiratory cycle, and the interaction of the two. A decomposition of a CVP cu...
We can present the sum of these three effects as a plane (mainly for fun).
Sample #Rstats code (tutorial) and sample data is available here:…

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