@AADmember here's what I'll tell my patients about #ZORYVE (#roflumilast) cream: It's used once a day for the treatment of #psoriasis in people 12 years or older. About 39% of patients achieve clear or almost clear skin with ZORYVE (roflumilast) cream after 8 weeks of use. 
The most common side effects (occurring in 1-3% of people) are diarrhea, headache, difficulty sleeping, nausea, pain at site of application, and infection. Only apply ZORYVE (roflumilast) cream to your psoriasis, and wash your hands after application.
DO NOT USE ZORYVE (roflumilast) cream if you are pregnant or breast feeding or if you have moderate to severe liver disease. The use of ZORYVE (roflumilast) cream with drugs that inhibit CYP3A4
(e.g., erythromycin, ketoconazole, fluvoxamine, enoxacin, cimetidine, or oral contraceptives containing gestodene and ethinyl estradiol) may increase roflumilast levels in your body and increase your risk of side effects.
In my opinion this is a significant advance in that it is not a topical steroid and will be safe to use on sensitive areas such as the face, genitals, underarms, groin, and breasts. We will need real world data to better define its role in psoriasis management.
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