Emma Hilton Profile picture
Aug 3, 2022 11 tweets 3 min read Read on X
@HarmoniaAtLast There are several mistakes in this thread. I barely know where to start.

First, males don't ovulate. They don't have ovaries, so cannot.
The hypothalamus/pituitary axis you describe is incomplete. Regarding the menstrual cycle, it is a HP*G* axis, where G is short for "gonad", in this case, the ovary.
There is feedback between all three components to produce a menstrual cycle. That is, you need ovaries, and they release important signals to the hypothalamus and pituitary that are necessary for the cycle to exist.
One of those signals is estrogen which, contrary to your confident assertion that it is made in the pituitary, is made (along with progesterone) in the ovary.
The surge of estrgoen experienced shortly before ovulation is derived from the ovary. It signals to the pituitary to produce a surge of luteinising hormone that triggers ovulation, where ovulation is the release of an egg from an ovary.
So while you may have a pituitary, it doesn't produce estrogen around ovulation, because that happens in the ovary. Which you don't have.
The ovary is not just a bag of eggs waiting to be told to throw one out. It is an interactive and crucial part of the physical and hormone changes that comprise the female menstrual cycle.
The source of progesterone in the female cycle is not the ovarian tissue proper, but the remains of the egg follicle itself (after it has popped one out). That is, the cyclical nature of progesterone is dependent on the process of ovulation.
Slowly??? 😂

Steroid hormone effects are elicited in seconds to minutes. 🤦‍♀️ Image
From elsewhere. Just inventing cycles from nowhere. ImageImageImage

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More from @FondOfBeetles

Aug 19
So, this paper is being widely circulated as a gotcha.

First thing, any author whose affiliation is "The University of the Sunshine Coast, Sippy Downs, Australia" is probably winning at life.

But let's talk about bird sex.

royalsocietypublishing.org/doi/10.1098/rs…
Birds use genetic sex determination, just like humans.

The "make male" gene for humans is called SRY, and it lives on the Y chromosome.

If you have functional SRY and its downstream transcriptional storm, you will make testes and make male.
Birds differ. Their "make male" gene is called DMRT1.

It pretty much works like SRY, in that it's immediate downstream target is the parallel gene in both humans and parrots, and the ensuing transcriptional storm triggers testes development (testes being male, of course).
Read 15 tweets
Aug 9
"This model of estradiol’s role in improving resistance to wound sepsis predicts at least four “sexes” across two treatment groups: females who are in the proestrus phase, females who are in the diestrus phase, females who are postmenopausal, and males."

This is Sarah Richardson, of the Fuentes review.

Four "sexes", three of them female and the other male. JFC.


Also in the frame as new sexes, fat men, pregnant women and children. JFC.scholar.harvard.edu/files/srichard…
A cell line derived from an unusual cervical cancer (one that spontaneously immortalised) is not even "human", let alone "female", apparently.

It's cervical cancer cell line. Only women have cervices (pl?). JFC.
Read 9 tweets
Aug 4
An interesting article from Professor Andrew Sinclair here, criticising World Athletics proposals to SRY screen their elite female athlete cohort.

It’s a classic. Arguments from authority. Cherry-picking. Doesn’t appear to have read the policy. theconversation.com/world-athletic…
A half-truth.

Apparently-female athletes who test positive for SRY will have a consultation with WA, with a view to medical assessment to better understand any medical conditions (DSDs) they have.

It is this diagnosis that will determine eligibility (or not). Image
After a primer on sex development, Sinclair tries a gotcha.

Describing Swyer Syndrome and CAIS, he argues these athletes would be unfairly excluded.

But WA makes it clear that CAIS is exempt from exclusion. It’s in both the policy and the press release. I doubt Swyer would be excluded either.Image
Read 8 tweets
Jul 28
Ok.

Let’s take Kelly’s penalty at 110 kph and Isak’s belter as 108 kph.

First up, Isak’s belter was from outside the penalty area, under defensive pressure, on the run and without perfect body positioning.

Compare. Image
Image
That Kelly put 110 kph on a penalty is astonishing. That Isak managed to get 108 kph out of this belter is astonishing.

Isak could put 110 kph on a penalty with his eyes closed. Kelly will never get 108 kph on a 20-yard shot she digs out from under her.

No shade.
Much has been made of Kelly’s approach. And her technique is *chef’s kiss*

Now imagine a man with the same expert technique, and who puts in as much % max effort as Kelly?

The ball’s going faster.
Read 5 tweets
Jul 25
Five years ago, I gave a speech comparing sex denialism to creationism.

At the time, my partner-in-crime, Colin Wright, and I were near-lone academic voices willing to stand up and say “Biology! We have a problem!”

@SwipeWright Image
Reflecting, back in 2020, on that state of affairs:

“[That] there are two sexes, male and female is apparently something that biologists do not think needs to be said.

I think they are wrong.”
Since then, biologists with far more authority than an unknown developmental biologist who was trying to work out how nerves navigate over muscles and an unknown evolutionary biologist who was studying what makes insects mad have spoken up.

And their voices are much welcomed.
Read 9 tweets
Jul 23
It took Naomi Cunningham a single minute with a medic under oath to get a straight answer to a question that nobody wants to answer. Image
Crickets. Image
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Crickets. Image
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Read 6 tweets

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